Rchr
J-GLOBAL ID：200901008854799290
Update date: Sep. 01, 2022
Wakagi Takayoshi
ワカギ タカヨシ | Wakagi Takayoshi
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Research field (3)：
Applied biochemistry
, Functional biochemistry
, Structural biochemistry
Research keywords (3)：
応用微生物学・応用生物化学
, Structure Biochemistry
, Applied Microbiology and Applied Biochemistry
Research theme for competitive and other funds (6)：
超好熱性古細菌の糖代謝
好酸好熱性古細菌のエネルギ-代謝
亜鉛を含む特異なフェレドキシンの構造と機能
Sugar metabolism of a hyperthermophilic archaea
Energy metabolism of a thermoacidophilic archaeon
Structure and function of a novel ferredoxin containing a zinc atom
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Papers (121)：
Zhen Yan, Akane Maruyama, Takatoshi Arakawa, Shinya Fushinobu, Takayoshi Wakagi. Crystal structures of archaeal 2-oxoacid: ferredoxin oxidoreductases from Sulfolobus tokodaii. SCIENTIFIC REPORTS. 2016. 6. 33061
T. Wakagi, H. Nishimasu, M. Miyake, S. Fushinobu. Archaeal Mo-Containing Glyceraldehyde Oxidoreductase Isozymes Exhibit Diverse Substrate Specificities through Unique Subunit Assemblies. PloS one. 2016. 11. e0147333
Lian-Hua Xu, Haruo Ikeda, Ling Liu, Takatoshi Arakawa, Takayoshi Wakagi, Hirofumi Shoun, Shinya Fushinobu. Structural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenase. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2015. 99. 7. 3081-3091
Kentaro Suzuki, Akane Hori, Kazusa Kawamoto, Ratna Rajesh Thangudu, Takuya Ishida, Kiyohiko Igarashi, Masahiro Samejima, Chihaya Yamada, Takatoshi Arakawa, Takayoshi Wakagi, et al. Crystal structure of a feruloyl esterase belonging to the tannase family: A disulfide bond near a catalytic triad. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2014. 82. 10. 2857-2867
Zhen Yan, Shinya Fushinobu, Takayoshi Wakagi. Four Cys residues in heterodimeric 2-oxoacid:ferredoxin oxidoreductase are required for CoA-dependent oxidative decarboxylation but not for a non-oxidative decarboxylation. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. 2014. 1844. 4. 736-743
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MISC (35)：
R Ishikawa, Y Ishido, A Tachikawa, H Kawasaki, H Matsuzawa, T Wakagi. Aeropyrum pernix K1, a strictly aerobic and hyperthermophilic archaeon, has two terminal oxidases, cytochrome ba(3) and cytochrome aa(3). ARCHIVES OF MICROBIOLOGY. 2002. 179. 1. 42-49
AV Puchkaev, T Wakagi, PRO de Montellano. CYP119 plus a Sultolobus tokodaii strain 7 ferredoxin and 2-oxoacid : ferredoxin oxidoreductase constitute a high-temperature cytochrome P450 catalytic system. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2002. 124. 43. 12682-12683
S Fushinobu, T Saku, M Hidaka, SY Jun, H Nojiri, H Yamane, H Shoun, T Omori, T Wakagi. Crystal structures of a meta-cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) complexed with cleavage products. PROTEIN SCIENCE. 2002. 11. 9. 2184-2195
Acyl-intermediate structure of the extended-spectrum classA beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin and benzylpenicillin. J. Biol. Chem. 2002. 277, 46601-46608
Trimeric crystal structure of the glucoside hydrolase family-42 beta-galactosidase from Thermus thermophilus A4 and its complex structure with galactose. J. Mol. Biol. 2002. 322(1), 79-91
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Books (7)：
アーキア生物学 日本Archaea研究会 監修・石野 良純・跡見 晴幸編著
共立出版 2017 ISBN:9784320057852
21世紀のバイオサイエンス・実験農芸化学
朝倉書店 2013 ISBN:9784254431155
「生化学辞典」第四版 今堀和友・山川民夫監修、分担執筆
東京化学同人 2008
『構造生物学 - ポストゲノム時代のタンパク質研究-』 (倉光成紀・杉山政則編) 分担執筆
共立出版 2007
『古細菌の生物学』(古賀洋介・亀倉正博編)分担執筆
東京大学出版会 1998
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Works (4)：
ADPをリン酸供与体とする新規ヘキソキナーゼの結晶構造と機能解析
2000 -
コプラナーポリ塩化ビフェニル(Co-PCB)分解系酵素の機能構造解析とダイオキシン類分解系酵素の分子モデリング
2000 -
Crystallography and functional analysis of a novel ADP-dependent hexokinase
2000 -
Structural and functional studies on Co-PCB-degrading enzyme system and mdecular modeling of dioxin-degrading enzymes.
2000 -
Education (4)：
- 1978 The University of Tokyo
- 1978 The University of Tokyo Graduate School, Division of Agricultural Science
- 1971 The University of Tokyo Faculty of Science
- 1971 The University of Tokyo Faculty of Science
Professional career (1)：
Doctor of Agriculture (The University of Tokyo)
Association Membership(s) (5)：
極限環境微生物学会
, 日本分子生物学会
, 日本蛋白質科学会
, 日本農芸化学会
, 日本生化学会
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