Rchr
J-GLOBAL ID：200901022414300873
Update date: Feb. 01, 2024
Hisatomi Osamu
ヒサトミ オサム | Hisatomi Osamu
Affiliation and department：
Job title：
Associate Professor
Research field (2)：
Molecular biology
, Biophysics
Research keywords (7)：
DNA結合タンパク質
, オーレオクローム
, 転写因子
, LOVドメイン
, 光受容
, Animal Physiology and Metabolism
, Molecular Biology
Research theme for competitive and other funds (30)：
- 2019 - 2022 Molecular mechanisms for conversion and transduction of light signal in a light-activatable transcription factor
- 2014 - 2017 Photoregulation of gene expression and enzymatic activity by dimerization of LOV protein
- 2012 - 2015 The study of light-induced structural change and DNA binding formation in Aureochrome with NMR
- 2011 - 2013 オーレオクロームによる光情報受容と転写調節機構研究の新展開
- 2010 - 2012 Molecular mechanism of a light-regulated transcription factor,aureochrome.
- 2009 - 2011 Ground study for researches with the newt Cynops pyrrhogaster
- 2006 - 2007 Photoreceptome解析による動物の光受容システムの進化及び多様性の研究
- 2005 - 2005 Photoreceptome研究による動物の光受容システムの起源及び多様性の解明
- 2004 - 2005 蚊の炭酸ガスセンサー受容蛋白質の同定と単離
- 2004 - 2005 惑星科学的衝撃に対する核酸・タンパク質構造の耐性
- 2003 - 2004 Exploration of regeneration of newt vision at the molecular level
- 2000 - 2002 Expression of exogenous genes in regenerating newt retina
- 1999 - 2001 Analyses of direct action of light on fish chromatophores
- 1999 - 2001 Analysis of transaction mechanism of visual information by direct observasion of interaction among functional proteins.
- 1997 - 1998 脊椎動物の視物質の多様性と色覚の起源
- 1997 - 1998 Diversities of proteins which participate in photoreception of vertebrate visual cells.
- 1996 - 1996 光受容に関与するタンパク質の分子進化
- 1995 - 1996 Photoreception of UV-sensitive pigments
- 1995 - 1996 Molecular Mechanism of Adaptation of Visual Cells
- 1995 - 1995 光受容に関与するタンパク質の分子進化
- 1994 - 1994 順応に関与する視細胞特異的カルシウム結合タンパク質
- 1994 - 1994 脊椎動物視物質の分子進化
- 1993 - 1994 FUNCTIONAL ANALYSIS OF VISUAL PIGMENTS BY CASSETTE CHIMERA METHOD
- 1993 - 1993 Sモジュリンによる視細胞の順応メカニズム
- 神経組織の再生機構
- 神経情報伝達系の分子進化
- 視覚の分子メカニズム
- Mechanism of Regeneration of nerve system
- Molecular evolution in nervous signal transduction system
- Molecular mechanism of vision
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Papers (60)：
-
Akihiro Tsuji, Hayato Yamashita, Osamu Hisatomi, Masayuki Abe. Dimerization processes for light-regulated transcription factor Photozipper visualized by high-speed atomic force microscopy. Scientific Reports. 2022. 12. 1
-
Hiroto Nakajima, Itsuki Kobayashi, Yumiko Adachi, Osamu Hisatomi. Transmission of light signals from the light-oxygen-voltage core via the hydrophobic region of the β-sheet surface in aureochrome-1. Scientific Reports. 2021. 11. 1
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Itsuki Kobayashi, Hiroto Nakajima, Osamu Hisatomi. Molecular Mechanism of Light-Induced Conformational Switching of the LOV Domain in Aureochrome-1. Biochemistry. 2020. 59. 28. 2592-2601
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Samu Tateyama, Itsuki Kobayashi, Osamu Hisatomi. Target Sequence Recognition by a Light-Activatable Basic Leucine Zipper Factor, Photozipper. Biochemistry. 2018. 57. 47. 6615-6623
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Hiroyuki Tsukuno, Kohei Ozeki, Itsuki Kobayashi, Osamu Hisatomi, Hiroyuki Mino. Flavin-Radical Formation in the Light-Oxygen-Voltage-Sensing Domain of the Photozipper Blue-light Sensor Protein. The journal of physical chemistry. B. 2018. 122. 38. 8819-8823
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MISC (88)：
Books (3)：
-
ロドプシンとアイオドプシン(共著)
光シグナルトランスダクション(Springer) 1999
-
Evolution of visual pigments and related molecules.
Rhodopsin and phototransduction(Wiley, Chichester)(Novartis Foundation Symposium 224) 1999
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Divergence of primate visual pigments.
Recent Advances in Physiological Anthropology (Kyushu University Press) 1999
Lectures and oral presentations (20)：
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1P124 Real-time analyses of a bHLH transcription factor(Protein engineering, evolutionary engineering, nucleic acid-binding proteins, and nucleic acid,Oral Presentations)
(Biophysics 2007)
-
1P123 DMA binding analyses of bHLH transcription factors by FRET measurements(Nucleic acid-binding proteins,Poster Presentations)
(Biophysics 2007)
-
Real-time analyses of HLH transcription factors
(COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 2007)
-
Analyses of stathmin family proteins in regenerating newt retinas
(ZOOLOGICAL SCIENCE 2006)
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Analysis of neurod4, a basic helix-loop-helix transcription factor, involved in newt retina regeneration
(ZOOLOGICAL SCIENCE 2006)
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Works (34)：
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光制御型転写因子オーレオクロームの機能メカニズム
2011 -
-
オーレオクロームによる光情報受容と転写調節機構研究の新展開
2011 -
-
光制御型転写因子オーレオクロームの機能メカニズム
2010 -
-
アカハライモリの資源化とモデル動物化を支える情報・技術基盤の研究
2010 -
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アカハライモリの資源化とモデル動物化を支える情報・技術基盤の研究
2009 -
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Education (4)：
- - 1990 Tohoku University
- - 1990 Tohoku University Graduate School, Division of Natural Science
- - 1982 Tohoku University Faculty of Science
- - 1982 Tohoku University Faculty of Science
Professional career (1)：
- Dr. of Science (Tohoku University)
Work history (4)：
- 1990 - 1998 Osaka University
- 1990 - 1998 Osaka University, Assistant Professor
- 1998 - - 大阪大学 助教授
- 1998 - - Osaka University, Associate Professor
Committee career (8)：
Association Membership(s) (7)：
日本動物学会近畿支部会
, 視覚科学フォーラム
, 日本進化学会
, The Association for Research in Vision and Ophthalmology
, 日本比較生理生化学会
, 日本動物学会
, 日本生物物理学会
