Research field (6):
Hematology and oncology
, Cardiology
, Internal medicine - General
, Cell biology
, Biological, health, and medical informatics
, Software
Research keywords (11):
coagulation
, clinical research
, clinical trial
, artificial intelligence
, computer simulation
, 血管内皮
, von Willebrand因子
, 血小板
, 抗血栓症療法
, 血栓症
, 心筋梗塞
Research theme for competitive and other funds (17):
2019 - 2024 細胞活性化時の生理機能変化を担う「分子レバレッジ機構」の解明
2018 - 2021 Antithrombogenic/flexible carbon-based nano-coating for superelastic Nitinol alloy stent in peripheral arterial disease.
2017 - 2019 スーパーコンピューターによる「分子レバレッジ」仮説の検証
2012 - 2017 血小板細胞の構成論的理解による心筋梗塞発症メカニズムの理解と制御法の開発
2013 - 2016 Elucidation of smoking-sensitive genes in chronic obstructive pulmonary disease with genomic analysis
2009 - 2011 心筋梗塞の発症にかかわる血小板活性化におけるミトコンドリアの役割の研究
2008 - 2010 Individualization of anticoagulation therapy of warfarin based on pharmacogenetic information
2007 - 2008 局所血管機能の調節における血小板由来マイクロパーティクルの役割の検討
2005 - 2006 Clarification of the Mechanism of Arterial Thrombus Formation by Dynamic Functional Imaging of Platelets
2003 - 2005 Redox-regulation by active oxygen species / nitric oxide in cardiovascular system
2003 - 2004 Mechanism of Procoagulant Activity Appearing on the Surface of Activated Platelet and New Development of Anttithrombotic Therapy by Its Inhibition.
2002 - 2003 An attempt to clarify the cause of "Pokkuri disease", a special type of sudden cardiac death, via Forensic Medicine.
2001 - 2002 The mechanism of platelet thrombus formation at site of endothelial damage under blood flow conditions
Shinya Goto, Shinichi Goto. Extensive LDL-cholesterol lowering by PCSK9 inhibitor on the risk of venous thrombosis. European heart journal. Cardiovascular pharmacotherapy. 2024
Shinya Goto, Shinichi Goto. Extensive lipid lowering, thickness of the fibrous caps, and plaque stability. European heart journal open. 2024. 4. 4. oeae056
Masamitsu Nakayama, Shinichi Goto, Shinya Goto. Development of the Integrated Computer Simulation Model of the Intracellular, Transmembrane, and Extracellular Domain of Platelet Integrin α IIb β 3 (Platelet Membrane Glycoprotein: GPIIb-IIIa). TH open : companion journal to thrombosis and haemostasis. 2024. 8. 1. e96-e105
Deborah M Siegal, Frederik H Verbrugge, Anne-Celine Martin, Saverio Virdone, John Camm, Karen Pieper, Bernard J Gersh, Shinya Goto, Alexander G G Turpie, Pantep Angchaisuksiri, et al. Country and health expenditure are major predictors of withholding anticoagulation in atrial fibrillation patients at high risk of stroke. Open heart. 2023. 10. 2
Marita Knudsen Pope, Trygve S Hall, Saverio Virdone, Dan Atar, A John Camm, Karen S Pieper, Petr Jansky, Sylvia Haas, Shinya Goto, Elizaveta Panchenko, et al. Rhythm versus rate control in patients with newly diagnosed atrial fibrillation - Observations from the GARFIELD-AF registry. International journal of cardiology. Heart & vasculature. 2023. 49. 101302-101302
Shinichi Goto, Hideki Oka, Kengo Ayabe, Hiroto Ybushita, Terumitsu Hasebe, Hideo Yokota, Shu Takagi, Motoaki Sano, Shinya Goto. Potential Explanation of the Mechanism for Loss of Function with G233D Mutation in Platelet Glycoprotein Ib[alpha]: Results fromMolecular Dynamics Simulation. CIRCULATION RESEARCH. 2019. 125
Deepak L. Bhatt, Kim Fox, Robert A. Harrington, Lawrence A. Leiter, Shamir R. Mehta, Tabassome Simon, Marielle Andersson, Anders Himmelmann, Wilhelm Ridderstråle, Claes Held, et al. Rationale, design and baseline characteristics of the effect of ticagrelor on health outcomes in diabetes mellitus patients Intervention study. Clinical Cardiology. 2019. 42. 498-505
Yong Huo, Young Hoon Jeong, Yanjun Gong, Daowen Wang, Ben He, Jiyan Chen, Guosheng Fu, Yundai Chen, Jianping Li, Yi Li, et al. 2018 update of expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI. Science Bulletin. 2019. 64. 166-179
2023/06 - The Japanese Society of Thrombosis and Hemostasis Okamoto Shosuke Award Antithrombotic Therapy in Cardiology
2023/01 - Matsumae Shigeyoshi Memorial Award Clinical and Basic Research to Overcome Thrombotic Diseases
2022/01 - akatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering Grand Prix Award New Biomedically Engineered Multi-Dimensional Data Analysis Method for Personalized Medicine
2018 - American Journal of Cardiology 2018: Outstanding reviewer award, the American Journal of Cardiology
2017 - European Journal of Internal Medicine Outstanding reviewer award, European Journal of Internal Medicine 傑出査読賞
2017 - The American Heart Journal Outstanding reviewer award, the American Heart Journal 傑出査読賞
2003/03 - Young Investigator Research Awards in Thrombosis sponsored by the Council on Arteriosclerosis, Thrombosis, and Vascular Biology of the American Heart Association Finalist for the Young Investigator Award