Yoshida Yasuhiro

2022 - 2026 硬組織/材料界面の感染・接着制御による骨再生と歯の再建技術の高機能化

2022 - 2025 湿性硬組織に接着する機能性分子の理論設計と保存治療系歯学臨床への応用

2022 - 2025 Development of bone regeneration control technology for the treatment of craniosynostosis

2020 - 2023 抗菌性および脱灰予防効果を持つ歯科用フィラーの開発

2020 - 2023 Development of micro/nano-patterns to create periodontal ligament sheets with three-dimensionally structures by guiding stem cells

2020 - 2023 生体硬組織に接着する吸収性素材の設計開発と保存修復・歯内療法・歯周治療への応用

2018 - 2022 Biodegradable adhesive gel as a bone graft extender

2019 - 2021 リン酸化プルランの大量・精密製造技術の確立と短期骨再生を可能とするペースト状人工骨の開発

2017 - 2020 Studies on the production for an innovative endodontic material having both bonding effectiveness and drug effectiveness, and the clinical application.

2016 - 2018 Development of new tooth adhesives with a sensing capability of debonding and release functions of antibacterial and regenerative agents

2015 - 2018 Development of new bone prosthetic material using iPS cell and phosphorylated pullulan

2015 - 2017 test

2014 - 2017 Practical use of materials for endodontic treatment to promote the reproduction of the hard tissue having an antibacterial effect

2014 - 2016 接着性と硬組織誘導能を併せ持った世界初の高機能歯内療法用材料の開発・海外展開

2012 - 2016 リン酸化プルランを用いた世界初の多目的接着性人工骨の開発

2010 - 2015 Creation of binding growth factors by molecular evolutionary engineering and their medical applications

2014 - 2015 Development of antibacterial materials for prevention and treatment of peri-implantitis

2013 - 2015 感染を防止し,骨再生を促進する革新的インプラントの開発

2013 - 2014 可視光硬化型ゼラチンを用いた革新的軟骨再生療法

2010 - 2014 Effect of functional monomers and photo-initiators in dental adhesive: molecular level analysis

2012 - 2013 Challenge to the world's first drug delivery system having a drug-concentration sensing function

2011 - 2013 Comprehensive analysis of functional monomer in dental adhesives using molecular-level analysis technique and investigation of the most suitable composition of adhesives

2011 - 2013 Development of the multipurpose adhesive system using Drug Delivery for Improved Direct pulp capping, Pulpotomy, and Periodontal treatment

2011 - 2012 リン酸化プルラン含有人工骨の硬組織接着メカニズムの解明と最適化

2011 - 2012 Neural regeneration in spinal cord injury using combination of photoreactive gelatin and a fusion protein of hepatocyte growth factor

2010 - 2012 A newly biodegradable bone cement inducing osteoanagenesis

2010 - 2011 Targeting DDS with sensing function of tissular and environmental changes

2009 - 2011 Nano-scale analysis and control of biomaterial-hard tissue interfaces.

2008 - 2010 Detection of nano-controlled molecular interaction of functional monomers at adhesive interfaces for hard tissue reconstruction

2009 - 2009 新規持続性う蝕・歯周病予防剤の口腔細菌叢への影響と安全性評価

2007 - 2009 Creation of growth factors binding to metal or ceramic for and their medical applications

2006 - 2009 Relation between the molecular structure of functional monomers and their interaction on apatite surface

2008 - 2008 口腔環境モデルによる抗菌物質デリバリーシステムの機能評価

2006 - 2008 High Performance Ti implant by photo-immobilization of cytokine and its effect oncell adhesion, proliferation and differentiation

2005 - 2008 Analysis of the nano-interface between implant and hard tissue

2005 - 2008 Newly developed bio-active implant by minute control of apatite coating layer.

2007 - 2007 ポリリン酸処理によるチタンインプラントの高機能化

2006 - 2007 短波長レーザーによる照射歯面の構造解析と歯科用レーザーへの応用

2006 - 2007 High functional nanobio surface modification of titanium implant with bone morphogenetic protein

2006 - 2007 Evaluation of liver damage by direct pulp capping and development of functional materials for pulp capping with biocompatibility and tissue degeneration

2006 - 2007 新規多糖誘導体リン酸化プルランを用いた硬組織用ドラッグデリバリーシステムの開発

2005 - 2007 Synthesis of a novel functional monomer and development of an adhesive system appropriate to laser-irradiated dental tissues

2006 - 2006 高齢者の口腔ケアを目指した抗菌性簡易歯質コーティング材の開発

2004 - 2006 Preparation of self-organized nano-structured apatite and the protein adsorption property

2004 - 2005 ワックスの操作性を具備した光重合型義歯床用レジンの開発

2004 - 2005 Development and establishment of high performance functional monomers

2004 - 2005 チタン表面への生体分子および細胞接着挙動のナノレベル・2次元・リアルタイム測定

2004 - 2005 Development of functional Ti implants with release of growth factors

2003 - 2005 Short- and long-term bonding effectiveness of simplified-step adhesives bonded to tooth substrate with clinical smear-layer

2002 - 2004 Establishment of a autologous cell transplantion method using mesenchymal stem cells for perio-dontal tissue and alveolus bone regeneration.

2002 - 2003 内分秘撹乱作用に対応した歯科用レジンの開発

2002 - 2003 Development of the HEMA free total-etch adhesive system

2002 - 2003 Theoretical molecular-design of a functional monomer for development of high-functinally adhesives

2001 - 2003 Control of interface between tooth tissue and resin by amino acid derivative

2000 - 2001 歯質・修復物接着界面におけるマイクロクラック発生メカニズムの検討

1999 - 2001 Chemical Modification of Adhesion Motif onto Apatite-Collagen Laminated Composites

1997 - 1999 Development of bone cement with affinity bio-adhesion

1996 - 1996 象牙質接着界面における潜在疲労破壊の理論的解析

機能性生体材料の開発に関する研究

歯科用インプラントの表面改質に関する基礎的研究

象牙質およびエナメル質接着システムに関する基礎的研究

Dvelopment of functional biomaterials

Fundamental studies on surface modification of dental implant materials

Fundamental Studies on dentine and enamel bonding system