Rchr
J-GLOBAL ID:200901025126403802   Update date: Oct. 04, 2023

Takeuchi Kenji

タケウチ ケンジ | Takeuchi Kenji
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): http://www.setsunan.ac.jp/
Research field  (2): Pharmaceuticals - health and biochemistry ,  Molecular biology
Research theme for competitive and other funds  (5):
  • Regulatory mechanism for the c-fos expression in HGF/SF and EGF signaling pathway
  • HGF/SFとEGFの情報伝達系の比較によるc-Fos発現制御機構に関する検討
  • 抗癌剤の作用機構の解明
  • 抗癌剤耐性克服を利用した新しい癌治療法の確立
  • 抗癌剤に対する耐性機構の解明
Papers (15):
  • Yamazawa R, Kuwana R, Takeuchi K, Takamatsu H, Nakajima Y, Ito K. Identification of the active site and characterization of a novel sporulation-specific cysteine protease YabG from Bacillus subtilis. The Journal of Biochemistry. 2022. 171. 3. 315-324
  • K. Takeuchi, F. Ito and P. T. Thuong. Anti-Growth Activity of Tanshinone IIA towards Gefitinib-Sensitive and ?Resistant NonSmall Cell Lung Cancer Cells. International Journal of Plant Biology & Research. 2014. 2. 3. 1020-1024
  • P. T. Thuong, N. M. Khoi, H. Kanta, K. Takeuchi. Ent-Kaurane Diterpenoids from Croton Tonkinensis Induce Apoptosis in Colorectal Cancer Cells through the Phosphorylation of JNK Mediated by Reactive Oxygen Species and Dual-Specificity JNK Kinase MKK4. Anti-cancer agents in medicinal chemistry. 2014. 14
  • Maruyama S, Takeuchi K, Ito F, Kawasaki K. RecQ5 interacts with Rad51 and is involved in resistance of Drosophila to cisplatin treatment. Biological & Pharmaceutical Bulletin. 2012. 35. 11. 2017-2022
  • K. Takeuchi, Viet, K. Kawasaki, K. Nishio, F. Ito. JNK-Mediated FOXO Expression Plays a Critical Role in EGFR Tyrosine Kinase Inhibitor-Induced BIM Expression and Apoptosis. Journal of Cancer Therapy. 2012. 3. 4A. 424-434
more...
Lectures and oral presentations  (77):
  • ベトナム産植物由来成分Tanshinone IIAのヒト胃がん細胞株に対する細胞死誘導機構
    (日本薬学会第143年会)
  • Geobacillus stearothermophilus由来YabGプロテアーゼの機能解析
    (日本薬学会第143年会)
  • 新規トリプシン様システインプロテアーゼ YabG (sporopain) の基質認識に重要なグルタミン酸残基の同定
    (第95回日本生化学会大会)
  • EGFR-TKI耐性ヒト非小細胞肺がん細胞株のMEK阻害剤併用による耐性克服機序
    (第72回 日本薬学会関西支部総会・大会)
  • ベトナム産植物由来成分Pristimerin, Tanshinone IIAによるヒト胃がん細胞株に対するアポトー シス誘導機構
    (第72回 日本薬学会関西支部総会・大会)
more...
Education (2):
  • - 1992 Setsunan University Graduate School, Division of Pharmaceutical Sciences
  • - 1990 Setsunan University Faculty of Pharmaceutical Science
Professional career (2):
  • 薬学士 (摂南大学)
  • 博士(薬学) (摂南大学)
Association Membership(s) (3):
日本分子生物学会 ,  日本生化学会 ,  日本薬学会
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