Rchr

J-GLOBAL ID：200901026705987006 Update date: Oct. 15, 2024

Kurisu Genji

クリスゲンジ | Kurisu Genji

Affiliation and department：
Job title： Professor
Other affiliations (2)：

Protein Research Foundation Division of Database Research
Suranaree University of Technology Institute of Science

Homepage URL (2)： http://www.protein.osaka-u.ac.jp/crystallography/ , http://www.protein.osaka-u.ac.jp/crystallography/EngHP/

Research field (2)： Biophysics , Structural biochemistry

Research keywords (5)： Protein Data Bank , Structural Biology , Biophysics , Bioinorganic Chemistry , Protein Crystallography

Research theme for competitive and other funds (43)：

2023 - 2028 Photosynthesis ubiquity: Supramolecular complexes and their regulations to enable ph otosynthesis all around the globe
2023 - 2028 Photosynthesis ubiquity: Supramolecular complexes and their regulations to enable photosynthesis all around the globe
2023 - 2028 超分子複合体の静的高分解能構造解析で可視化する環境適応原理
2022 - 2027 Advanced development of Protein Data Bank extended as the Data-driven research platform
2020 - 2026 Molecular basis for dynamic communication between the photosynthetic organelles, chloroplast and pyrenoid

2022 - 2025 Structure-based metabolic engineering of algal H2 production (H2M)

2021 - 2024 Structural analysis of the complex between Fd and Fd-dependent proteins considering their redox states strictly

2018 - 2022 タンパク質構造解析のハイスループット化へ向けた装置開発

2017 - 2022 Research Support with Data Science for Promotion of Drug Development Related Life Science

2017 - 2022 Upgrading data validation and integration for Protein Data Bank

2018 - 2021 Structural study on the active binding of dynein/dynactin complex to the microtubule

2016 - 2021 New Photosynthesis : Re-optimization of the solar energy conversion system

2016 - 2021 Strategic Structural Study of the Protom Motive Force

2013 - 2019 Structural Studies on the transient macromolecular complexes formed upon photoacclimation

2015 - 2018 Structural analysis of cytochrome bd oxidase complex with substrate

2015 - 2018 The mechanisms to control electron transfer reactions in the homodimeric photosynthetic reaction center based on its molecular structure

2014 - 2018 Structural basis for cytoplasmic dynein regulation

2014 - 2018 Structural analysis of the axonemal dynein responsible for ciliary/flagellar beating

2012 - 2016 Comprehensive analysis of molecular interaction of ferredoxin and enzymes involved in redox metabolisms in chloroplast

2011 - 2015 Perturbation to the electron transfer and distribution due to the connection between ferredoxin and its partner proteins

2011 - 2014 X-ray structural analysis of the 380-kDa motor domain of cytoplasmic dynein

2011 - 2014 Dark-operative protochlorophyllide reductase and nitrogenase: common mechanism for reduction of stable multiple-bonds

2011 - 2014 Structural analysis of the entire electron transfer network of photosynthetic energy transduction for light-driven bio-hydrogen production

2010 - 2012 Structural analysis of the electron transfer complexes for understanding entirely the photosynthetic energy transduction

2009 - 2011 複合体X線解析で解明する葉緑体内還元力分配システムの構造基盤

2008 - 2010 Invention of a light-dependent nitrogenase from chlorophyll biosynthesis enzymes

2008 - 2009 巨大モーター蛋白質ダイニンのX線構造解析

2005 - 2009 Molecular Mechanism of energy transduction of dynein revealed by genetic engineering, structural and enzyme kinetics studies

2007 - 2008 膜面新規ヘム鉄の役割解明を目指す高等植物チトクロムb6f複合体のX線構造解析

2006 - 2007 巨大モーター蛋白質ダイニンのX線による原子レベル構造研究

2005 - 2007 複合体結晶構造解析で明らかにする高等植物に特有な光還元力分配システムの構造基盤

2003 - 2007 Molecular machinery regulating energy and metabolic networks in plant cells

2005 - 2006 光合成循環電子伝達を制御するチトクロム複合体とフェレドキシンとの相互作用解析

2005 - 2005 巨大モーター蛋白質ダイニンのX線結晶構造に基づいた機能解析

2004 - 2004 立体構造から探るフェレドキシン依存性循環電子伝達でのチトクロムb_6f複合体の役割

2003 - 2004 X線結晶解析法によるフェレドキシンと亜硫酸還元酵素による電子伝達複合体の構造研究

2003 - 2003 マラリア・アピコプラストのレドックス蛋白質群の探索と機能の解明

2001 - 2002 フェレドキシン依存性酵素とフェレドキシンとの複合体結晶構造の解析

2000 - 2002 Development of MrPDB, a full automatic software system of molecular replacement for protein

2001 - 2001 マラリア・アピコプラストのレドックス蛋白質群の探索と機能の解明

2000 - 2001 機能を制御する水素結合を直接見る金属蛋白質の超高分解能X線結晶解析

1998 - 2000 Establishment of the System for the Protein Data Bank Archiving in Japan

1998 - 1999 時間分割X線解析法によるUDP-Glcピロホスホリラーゼの反応機構の可視化

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Papers (170)：

Ginga Shimakawa, Manon Demulder, Serena Flori, Akihiro Kawamoto, Yoshinori Tsuji, Hermanus Nawaly, Atsuko Tanaka, Rei Tohda, Tadayoshi Ota, Hiroaki Matsui, et al. Diatom pyrenoids are encased in a protein shell that enables efficient CO2 fixation. Cell. 2024
Soichiro Seki, Tomoko Miyata, Naoko Norioka, Hideaki Tanaka, Genji Kurisu, Keiichi Namba, Ritsuko Fujii. Structure-based validation of recombinant light-harvesting complex II. PNAS Nexus. 2024. 3. 9
Poonam Deka, Shilpi Jaiswal, Parishmita Sarma, Debajit Bora, Takanori Nakane, Akihiro Kawamoto, Yusuke Ohnishi, Genji Kurisu, Sanjeev Pran Mahanta, Khaled Althubeiti, et al. Analysis of Solid-State Emission of the <i>p</i>-Bis(2,2-dicyanovinyl)benzene Analogue through Combined X-ray, Synchrotron, and Microcrystal Electron Diffraction. Crystal Growth & Design. 2024
Nawee Jantarit, Hideaki Tanaka, Yuxi Lin, Young-Ho Lee, Genji Kurisu. Crystal structure of pectocin M1 reveals diverse conformations and interactions during its initial step via the ferredoxin uptake system. FEBS open bio. 2024
Katsuya Takahashi, Yongchan Lee, Angela Fago, Naim M Bautista, Jay F Storz, Akihiro Kawamoto, Genji Kurisu, Tomohiro Nishizawa, Jeremy R H Tame. The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM. Nature Communications. 2024. 15. 1. 6505-6505

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MISC (81)：

慈幸千真理, 三角裕子, 栗栖源嗣, 森本幸生, 月原冨武, GERLE Christoph. Preparation of mammalian mitochondrial FoF1ATP synthase for high-resolution structural analysis. 日本生体エネルギー研究会討論会講演要旨集. 2023. 49th
星野宏季, 宮崎剛亜, 伏見圭司, 田中秀明, PARK Enoch Y, 栗栖源嗣, 成川礼. The X-ray crystal structure analysis of cyanobacteriochrome cce_4193g1 showing unique chromophore binding mode. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
中根崇智, 川本晃大, 牧野文信, 牧野文信, 西嶋雅彦, 西嶋雅彦, 難波啓一, 栗栖源嗣. 蛋白質研究所と生命機能研究科におけるMicroED構造解析の現状. 日本結晶学会年会講演要旨集. 2022. 2022
横地政志, BEKKER Gert-Jan, 栗栖源嗣. Extension of wwPDB core archive with RDF graph data model. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
秋山智有, 乗岡尚子, 岡直宏, 伊佐治由貴, 仲庭哲津子, 東田怜, 田中秀明, 田中秀明, 栗栖源嗣, 栗栖源嗣, et al. In-vitro reconstitution of light-harvesting complexes of a siphonous green alga, Codium fragile. 日本植物生理学会年会(Web). 2021. 62nd

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Patents (3)：

結晶観察装置
蛋白質結晶化装置
1). 分注シール装置およびウェル開口部のシール方法

Books (15)：

創薬研究のための相互作用解析パーフェクト : 低中分子・抗体創薬におけるスクリーニング戦略と実例、in silico解析、一歩進んだ分析技術まで
羊土社 2021 ISBN:9784758122566
Photosynthesis
2021 ISBN:9784254171761
Structural Proteomics
Springer 2021 ISBN:9781071614082
生命金属ダイナミクス : 生体内における金属の挙動と制御
エヌ・ティー・エス 2021 ISBN:9784860437060
化学便覧
丸善出版 2021 ISBN:9784621305218

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Lectures and oral presentations (12)：

Structural analysis for Fd-dependency in the Photosynthetic electron transport
(Biological Sciences Seminar Series, Purdue University 2024)
Protein Data Bank: A single global archive of experimentally determined macromolecular structures
(foundingGIDE Kick-off meeting 2024)
Structural studies on the microtubule-binding domain of dynein
(24th Korean Peptide and Protein Society Symposium 2021)
光合成循環電子伝達に関わる分子装置の構造と機能
(京都大学理学研究科生物科学専攻植物学系セミナー 2021)
光合成循環電子伝達に関わる分子装置の構造と機能
(岡山大学異分野基礎科学研究所セミナー 2020)

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Works (4)：

Development of Protein Data Bank
KURISU Genji 2017 - 現在
Electron Microscopy Public Image Archiveの開発
2017 - 現在
Electron Microscopy Data Bankの開発
2017 - 現在
Biological Magnetic Resonance Data Bankの開発
2017 - 現在

Education (2)：

1992 - 1997 Osaka University Graduate School of Engineering Department of Applied Chemistry
1988 - 1992 Osaka University School of Engineering Department of Applied Chemstry

Professional career (1)：

Ph.D. in Applied Chemistry (Crystallography) (Osaka University)

Work history (14)：

2024/04 - 現在 Osaka University Institute for Protein Research Director
2022/01 - 現在 Suranaree University of Technology Institute of Science
2022/01 - 現在 Protein Research Foundation (Visiting Research Scholar)
2021/04 - 現在 Osaka University Institute for Open and Transdisciplinary Research Initiatives Professor (Concurrent)
2020/04 - 現在 Osaka University Graduate School of Engineering Professor (Concurrent)

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Committee career (11)：

2023/06 - 現在日本光合成学会常任幹事
2022/11 - 現在 Asian Crystallographic Association President
2022/01 - 現在 International Union of Crystallography Member of Committee on Data
2020/01 - 現在 International Union of Crystallography Member of Committee of Biological Macromolecules
2016/01 - 現在 Acta Crystallographica Section D Co-Editor

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Awards (8)：

2022/11 - The Japanese Biochemical Society JB Best Reviewer Award 2022
2020/04 - Commendation for Science and Technology by the Minister of Education, Science and Technology
2019/11 - Osaka Science Prize
2016/11 - The Research Awards, Crystallographic Society of Japan
2015 - 大阪大学総長奨励賞

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Association Membership(s) (10)：

Biophysical Society of Taiwan , The Botanical Society of Japan , THE BIOPHYSICAL SOCIETY OF JAPAN , THE JAPANESE SOCIETY OF PHOTOSYNTHESIS RESEARCH , 日本結晶学会 , PROTEIN SCIENCE SOCIETY OF JAPAN , THE CHEMICAL SOCIETY OF JAPAN , THE JAPANESE SOCIETY FOR SYNCHROTRON RADIATION RESEARCH , THE JAPANESE BIOCHEMICAL SOCIETY , THE JAPANESE SOCIETY OF PLANT PHYSIOLOGISTS

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