Rchr
J-GLOBAL ID:200901029052929250   Update date: Sep. 19, 2024

Yoshida Hiromi

ヨシダ ヒロミ | Yoshida Hiromi
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): https://www.med.kagawa-u.ac.jp/~xraylab/
Research field  (1): Structural biochemistry
Research keywords  (7): oxidoreductase ,  Carbohydrate-active enzymes ,  rare sugar ,  構造生物学 ,  タンパク質工学 ,  structural biology ,  protein engineering
Research theme for competitive and other funds  (14):
  • 2016 - 2019 Elucidation of molecular mechanism of novel iron-sulfur flavoprotein cytochrome dehydrogenase
  • 2016 - 2019 X-ray structure analysis of the enzyme for rare sugar production and elucidation of the mechanism of its thermal stability
  • 2015 - 2018 Analysis of the species-specific molecular mechanism of C. perfringens-specific lytic enzyme Psm and its application
  • 2015 - 2018 Cell wall peptidoglycan recognition/hydrolysis mechanisms of Clostridium perfringens lytic enzymes based on X-ray structures
  • 2013 - 2016 The study on inclusive catalytic reaction mechanism of the enzymes used for rare sugar production on the basis of X-ray structures in complexes with rare sugars
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Papers (82):
  • Hiromi Yoshida, Naho Yamamoto, Lin Hai Kurahara, Ken Izumori, Akihide Yoshihara. X-ray structure and characterization of a probiotic Lactobacillus rhamnosus Probio-M9 L-rhamnose isomerase. Applied Microbiology and Biotechnology. 2024. 108. 1. 249
  • Ratna A. Utami, Hiromi Yoshida, Lydia H. Kartadinata, Virgi A. Abdillah, Cut R. Faratilla, Debbie S. Retnoningrum, Wangsa T. Ismaya. Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon. Acta Crystallographica Section F Structural Biology Communications. 2023. 79. 12. 301-307
  • Miku Miyoshi, Akihide Yoshihara, Susumu Mochizuki, Shiro Kato, Hiromi Yoshida, Tatsuhiro Matsuo, Yuka Kishimoto, Tadao Inazu, Isao Kimura, Ken Izumori, et al. Safety evaluation and maximum use level for transient ingestion in humans of allitol. Bioscience, Biotechnology, and Biochemistry. 2023. 87. 10. 1193-1204
  • Debbie S Retnoningrum, Hiromi Yoshida, Ismiana Pajatiwi, Rahmat Muliadi, Ratna A Utami, Anita Artarini, Wangsa T Ismaya. Introducing Intermolecular Interaction to Strengthen the Stability of MnSOD Dimer. Applied biochemistry and biotechnology. 2023
  • Akihide Yoshihara, Yota Takamatsu, Susumu Mochizuki, Hiromi Yoshida, Ryoji Masui, Ken Izumori, Shigehiro Kamitori. Structural and biochemical characterizations of Thermus thermophilus HB8 transketolase producing a heptulose. Applied microbiology and biotechnology. 2023. 107. 1. 233-245
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MISC (123):
  • 山本菜帆, 吉田裕美, 望月進, 何森健, 吉原明秀. Klebsiella pneumoniae40b由来ポリオールデヒドロゲナーゼを用いたケトース・糖アルコール間の効率的な転換. 日本農芸化学会西日本支部大会およびシンポジウム講演要旨集. 2023. 2023 (CD-ROM)
  • 綿貫花菜, 高松陽太, 望月進, 花木祐輔, 吉田裕美, 神鳥成弘, 何森健, 吉原明秀. Thermus thermophilus HB8由来トランスケトラーゼを用いた七炭糖生産と効率的な生産条件の検討. 日本農芸化学会西日本支部大会およびシンポジウム講演要旨集. 2023. 2023 (CD-ROM)
  • 塚本郁子, 吉田裕美, 神鳥成弘. Reaction of a rare sugar D-allose with bacterial allokinases. 日本糖質学会年会要旨集. 2022. 41st
  • 塚本郁子, 神鳥和代, 徳田雅明, 吉田裕美, 神鳥成弘. Enzymatic activities of human hexokinases to a rare sugar, D-allose. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 塚本郁子, 井上圭介, 前川聖, 神鳥和代, 徳田雅明, 吉田裕美, 神鳥成弘. Human hexokinase 3 has a high enzymatic activity to a rare sugar, D-allose. 日本糖質学会年会要旨集. 2021. 40th
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Patents (1):
Books (2):
  • SH Domains: Structure, Mechanisms and Applications
    Springer 2015 ISBN:9783319200972
  • Recent Res.Devel. Protein Eng.
    Research Signpost (ISBN: 81-7736-147-3) 2002
Lectures and oral presentations  (225):
  • Understanding the recognition of 1-deoxy rare sugar by Pseudomonas stutzeri L-rhamnose isomerase based on X-ray structure analyses
    (日本農芸化学会2024年度大会 2024)
  • 希少糖生産酵素の基質認識および触媒反応機構
    (23-1 バイオ・高分子研究会 2023)
  • X-ray structure of recombinant ribitol dehydrogenase from Klebsiella oxytoca
    (Rare Sugar Congress 2023 2023)
  • Expression and X-ray structure analysis of recombinant ribitol dehydrogenase from Klebsiella oxytoca
    (2023)
  • X-ray structure of L-Lactate oxidase from Enterococcus hirae in compl ex with D-lactate form provides insight into the product inhibition mode
    (2022)
more...
Works (4):
  • 希少糖生産酵素の触媒反応機構解明に向けた宇宙環境を利用した高品質タンパク質結晶生成と精密立体構造の解析
    2016 - 2017
  • 希少糖生産酵素の触媒反応機構解明に向けた宇宙環境を利用した高品質タンパク質結晶生成(第2回実験)と精密立体構造の解析
    2014 - 2015
  • 希少糖生産酵素の触媒反応機構解明に向けた宇宙環境を利用した高品質タンパク質結晶生成(第1回実験)と精密立体構造の解析
    2013 - 2014
  • 宇宙環境を利用した高品質タンパク質結晶生成(第6回実験)と精密立体構造の解析
    2012 - 2013
Education (5):
  • - 1999 Tokyo University of Agriculture and Technology Graduate School, Division of Engineering Department of Biotechnology
  • - 1999 Tokyo University of Agriculture and Technology
  • - 1996 Tokyo University of Agriculture and Technology Graduate School, Division of Engineering Department of Biotechnology
  • - 1994 Tokyo University of Agriculture and Technology Faculty of Engineering Department of Biotechnology
  • - 1994 Tokyo University of Agriculture and Technology Faculty of Engineering
Professional career (2):
  • Doctor (Engineering) (Tokyo University of Agriculture and Technology)
  • Master (Engineering) (Tokyo University of Agriculture and Technology)
Work history (10):
  • 2009 - 現在 Tokyo University of Agriculture and Technology
  • 2007 - 現在 香川大学総合生命科学研究センター, 准教授
  • 2004 - 2007 Kagawa University Information Technology Center
  • 2002 - 2004 Laboratory of Biophysical Chemistry, University of Groningen (The Netherlands), Postdoctoral fellow
  • 2002 - 2002 海洋バイオテクノロジー研究所, 博士研究員
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Committee career (2):
  • 2017/03 - 2021/02 Japan Society for Bioscience, Biotechnology, and Agrochemistry member of editorial board of KAGAKU TO SEIBUTSU
  • 2017/03 - 2021/02 日本農芸化学会 和文誌編集委員
Association Membership(s) (5):
The Crystallographic Society of Japan ,  The Japanese Biochemical Society ,  Japan Society for Bioscience, Biotechnology, and Agrochemistry ,  Protein Science Society of Japan ,  The Society for Biotechnology
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