Rchr
J-GLOBAL ID:200901029591073938   Update date: Jun. 09, 2020

Sasai Ken

ササイ ケン | Sasai Ken
Affiliation and department:
Job title: Assistant Professor
Research field  (3): Medical biochemistry ,  Cell biology ,  Molecular biology
Research keywords  (6): Tumor microenvironment ,  MGMT ,  脳腫瘍 ,  Tumor microenvironment ,  MGMT ,  Glioma
Research theme for competitive and other funds  (3):
  • 2008 - MGMT 遺伝子の制御機構解明とグリオーマ治療への応用
  • 2008 - Gene Regulation of MGMT in Glioma
  • 2007 - ヒト正常細胞を用いた脳腫瘍発症メカニズムの分子生物学的解析
MISC (26):
more...
Lectures and oral presentations  (4):
  • GLI1 but not FOXM1 induces oncogenic transformation of immortalized astrocytes.
    (第31回日本分子生物学会年会(神戸) 2008)
  • Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a Smoothened inhibitor.
    (Keystone Symoisia: Molecular Targets for Cancer (Whistler, BA, Canada) 2007)
  • O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies.
    (Nature-CINO Conference: Oncogenes and Human Cancer-The Next 25 Years (Madrid, Spain) 2007)
  • Shh pathway activity is maintained in direct allografts of medulloblastoma cells whereas it is irreversibly lost in cell culture: Implications for preclinical studies of Smoothened antagonist.
    (97th Annual Meeting for American Association for Cancer Research (Washington DC, USA) 2006)
Education (3):
  • - 2000 The University of Tokyo
  • - 1997 The University of Tokyo
  • - 1995 The University of Tokyo
Professional career (1):
  • 博士(農学) (東京大学)
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