Rchr
J-GLOBAL ID：200901033506211267   Update date: Jul. 17, 2024

Masaya Imoto

イモト マサヤ | Masaya Imoto
Affiliation and department：
Juntendo University Graduate School of Medicine

About Juntendo University Graduate School of Medicine


Research field  (1)： Chemical biology
Research keywords  (1)： ケミカルバイオロジー
Research theme for competitive and other funds  (38)：
  • 2023 - 2026 細胞内alpha-Synuclein凝集制御機構を解析するケミカルバイオロジー
  • 2022 - 2025 Development of anti-Parkinson's disease drugs enhancing neuronal autophagy
  • 2021 - 2024 Elucidation of transmission and aggregation mechanisms of alpha-synuclein as a major component of Lewy body and development of disease-modifying therapies for synucleinopathies
  • 2021 - 2024 Studies on the regulatory mechanism of aggresome formatiion and clearance
  • 2018 - 2022 Identification of Parkinson's disease progression markers based on skeletal muscle-brain axis
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Papers (265)：
  • Yuki Date, Yukiko Sasazawa, Mitsuhiro Kitagawa, Kentaro Gejima, Ayami Suzuki, Hideyuki Saya, yasuyuki kida, Masaya Imoto, Eisuke Itakura, Nobutaka Hattori, et al. Novel autophagy inducers by accelerating lysosomal clustering against Parkinson's disease. eLife. 2024. 13
  • Tetsushi Kataura, Lucia Sedlackova, Congxin Sun, Gamze Kocak, Niall Wilson, Peter Banks, Faisal Hayat, Sergey Trushin, Eugenia Trushina, Oliver D. K. Maddocks, et al. Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models. Cell Death & Disease. 2024. 15. 5
  • Yusuke Hanaki, Yuki Shikata, Masayuki Kikumori, Mutsumi Okamura, Shingo Dan, Masaya Imoto, Kazuhiro Irie. In vivo anti-cancer activity of 10-methyl-aplog-1, a simplified analog of aplysiatoxin, and its possible signaling pathway associated with G1 arrest. Biochemical and Biophysical Research Communications. 2023
  • Yukiko Sasazawa, Sanae Souma, Norihiko Furuya, Yoshiki Miura, Saiko Kazuno, Soichiro Kakuta, Ayami Suzuki, Ryota Hashimoto, Hiroko Hirawake-Mogi, Yuki Date, et al. Oxidative stress-induced phosphorylation of JIP4 regulates lysosomal positioning in coordination with TRPML1 and ALG2. The EMBO Journal. 2022. 41. 22. e111476
  • Tetsushi Kataura, Lucia Sedlackova, Elsje G. Otten, Ruchika Kumari, David Shapira, Filippo Scialo, Rhoda Stefanatos, Kei-ichi Ishikawa, George Kelly, Elena Seranova, et al. Autophagy promotes cell survival by maintaining NAD levels. Developmental Cell. 2022. 57. 22. 2584-2598.e11
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MISC (35)：
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Patents (3)：
  • デフォスタチンの物質特許
  • イノスタマイシンの物質特許
  • 新規チロシンキナーゼ阻害剤の物質特許
Books (1)：
  • バイオの窓「大学における物取り研究」
    バイオサイエンスとインダストリー59: 43 (2001) 2001
Education (2)：
  • 1980 - Yamaguchi University Graduate School, Division of Agriculture 農芸化学専攻
  • 1978 - Yamaguchi University Faculty of Agriculture 農芸化学科
Professional career (1)：
  • 農学 (The University of Tokyo)
Work history (7)：
  • 2020/04 - 現在 慶應義塾大学 名誉教授
  • 2020/04 - 現在 Juntendo University Graduate School of Medicine
  • 2002/04 - 2020/03 Keio University Faculty of Science and Technology
  • 1996/04/01 - 2002/03/31 慶應義塾大学理工学部 ,助教授
  • 1991/04 - 1996/03 慶應義塾大学理工学部 ,専任講師
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Awards (4)：
  • 2018/03 - 日本農芸化学会 日本農芸化学会功績賞
  • 2009/03 - 日本農芸化学会 農芸化学研究企画賞
  • 2000/11 - 日本抗生物質学術協議会 住木・梅沢記念賞受賞
  • 1995/03 - 日本農芸化学会 日本農芸化学会奨励賞受賞
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