Rchr
J-GLOBAL ID：200901036866152058   Update date: May. 14, 2024

Okamoto Hiroaki

オカモト ヒロアキ | Okamoto Hiroaki
Affiliation and department：
Jichi Medical University School of Medicine, Department of Infection and Immunity, Division of Virology

About Jichi Medical University School of Medicine, Department of Infection and Immunity, Division of Virology


Job title： Professor
Homepage URL  (1)： http://www.jichi.ac.jp/virology/
Research field  (2)： Virology ,  Molecular biology
Research keywords  (22)： Fulminant hepatitis ,  Replication mechanism ,  Molecular epidemiology ,  Cell culture ,  Monoclonal antibody ,  Genetic mutation ,  Anellovirus ,  GB virus ,  Torque teno virus ,  Zoonosis ,  Hepatitis E virus ,  Hepatitis delta virus ,  Hepatitis C virus ,  Hepatitis B virus ,  Hepatitis A virus ,  Molecular cloning ,  分子ウイルス学 ,  ウイルス肝炎 ,  肝炎ウイルス ,  Molecular virology ,  Viral Hepatitis ,  Hepatitis viruses
Research theme for competitive and other funds  (16)：
  • 2023 - 2026 Study of Prevention, Pathological Development and Treatment for Hepatitis A and E Virus Infection
  • 2013 - 2015 Research on mechanism of hepatitis E virus egress utilizing membrane traffic
  • 2011 - 2012 Studies on the identification and acquisition mechanism ofcell-derived membrane on the surface of hepatitis E virus particles
  • 2010 - 2012 Research on release mechanism, genome mutations and cellular receptor of hepatitis E virus (HEV) using cell culture systems for HEV
  • 2007 - 2008 Characterization of hepatitis E virus (HEV) particles and analysis of replication mechanism by using a cell culture system for HEV
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Papers (716)：
  • Rei Hirano, Tatsuo Kanda, Masayuki Honda, Shuhei Arima, Mai Totsuka, Ryota Masuzaki, Shini Kanezawa, Reina Sasaki-Tanaka, Naoki Matsumoto, Hiroaki Yamagami, et al. Hepatitis E Virus Infection Caused Elevation of Alanine Aminotransferase Levels in a Patient with Chronic Hepatitis B and Choledocholithiasis. Reports. 2023. 6. 4. 55-55
  • Tatsuo Kanda, Reina Sasaki-Tanaka, Koji Ishii, Ryosuke Suzuki, Jun Inoue, Atsunori Tsuchiya, Shingo Nakamoto, Ryuzo Abe, Keiichi Fujiwara, Osamu Yokosuka, et al. Recent advances in hepatitis A virus (HAV) research and clinical practice guidelines for HAV infection in Japan. Hepatology Research. 2023
  • Shigeo Nagashima, Putu Prathiwi Primadharsini, Takashi Nishiyama, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform. JOURNAL OF VIROLOGY. 2023
  • Yuichi Yoshida, Asami Ito, Hisashi Eto, Akiko Suzuki, Tamami Abe, Kei Endo, Keisuke Kakisaka, Takayoshi Oikawa, Hidekatsu Kuroda, Akio Miyasaka, et al. Seroprevalence and incidence of hepatitis E virus infection in the general population of Iwate prefecture, Japan: A retrospective cohort study. Hepatology research : the official journal of the Japan Society of Hepatology. 2023
  • Masaharu Takahashi, Satoshi Kunita, Tsutomu Nishizawa, Hiroshi Ohnishi, Putu Prathiwi Primadharsini, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto. Infection Dynamics and Genomic Mutations of Hepatitis E Virus in Naturally Infected Pigs on a Farrow-to-Finish Farm in Japan: A Survey from 2012 to 2021. VIRUSES-BASEL. 2023. 15. 7
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MISC (676)：
  • Yuichi Yamazaki, Takashi Ueno, Takeshi Hatanaka, Satoshi Takakusagi, Daichi Takizawa, Atsushi Naganuma, Takashi Kosone, Hiroaki Nakajima, Ken Sato, Satoru Kakizaki, et al. Characteristics of cases of hepatitis E in Gunma prefecture: Small epidemics caused by the same subgenotype 3a strains. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2021. 36. 87-88
  • Putu Prathiwi Primadharsini, Shigeo Nagashima, Hiroaki Okamoto. Mechanism of Cross-Species Transmission, Adaptive Evolution and Pathogenesis of Hepatitis E Virus. VIRUSES-BASEL. 2021. 13. 5
  • 大城幸雄, 岡本宏明, 鈴木修司. わが国の臓器移植患者におけるE型肝炎ウイルス感染追跡調査. 肝臓. 2020. 61. Supplement 2
  • 大城 幸雄, 大和田 洋平, 稲垣 勇紀, 大河内 信弘, 岡本 宏明. 【A型・E型肝炎up-to-date】E型肝炎慢性化とその対策. 消化器・肝臓内科. 2019. 6. 1. 83-88
  • Putu Prathiwi Primadharsini, Shigeo Nagashima, Hiroaki Okamoto. Genetic Variability and Evolution of Hepatitis E Virus. VIRUSES-BASEL. 2019. 11. 5
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Patents (25)：
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Books (5)：
  • Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses
    Elsevier 2011
  • TT Viruses-The Still Elusive Human Pathogens. (jointly worked)
    Springer 2009 ISBN:9783540709718
  • Virus Taxonomy: Classification and Nomenclature of Viruses.Eighth Report of the International Committee on the Taxonomy of Viruses.(jointly worked)
    Elsevier/Academic Press 2005 ISBN:0122499514
  • Viral Hepatitis: Molecular Biology, Diagnosis, Epidemiology and Control.(jointly worked)
    Elsevier 2004 ISBN:0444514872
  • The use of a preS2-containing recombinant vaccine for the prevention of maternal transmission of hepatitis B virus in Indonesian neonates.(jointly worked)
    Viral Hepatitis and Liver Diseases 1994
Education (1)：
  • 1973 - 1979 Tohoku University Faculty of Medicine School of Medicine
Professional career (1)：
  • (BLANK) (Jichi Medical University)
Work history (6)：
  • 2020/04 - 現在 Jichi Medical University
  • 2020/04 - 現在 Jichi Medical University
  • 2003/04 - 2020/03 Jichi Medical University Professor
  • 1998 - 2003 Jichi Medical University
  • 1987 - 1998 Jichi Medical University
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Awards (4)：
  • 2008 - 第44回小島三郎記念文化賞
  • 2000 - ISI Citation Laureate Award
  • 1997 - 第1回日本肝臓学会賞(織田賞)
  • 1992 - 第2回日経BP技術賞大賞
Association Membership(s) (6)：
日本臨床ウイルス学会 ,  日本ウイルス学会 ,  日本内科学会 ,  日本消化器病学会 ,  日本肝臓学会 ,  American Society for Microbiology
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