Research theme for competitive and other funds (14):
2023 - 2026 疾患モデルを駆使した筋ジストロフィーの治療法開発
2024 - 2025 自己免疫性脳炎・脳症の診断材料の開発
2024 - 2025 自己免疫性脳神経炎の診断材料の 開発
2021 - 2024 Molecular pathogenesis of brain malformations in de novo postzygotic mutations in the brain
2021 - 2024 Functional analysis of dystrophin in blood-brain barrier and its relevance to epilepsy
2018 - 2021 Elucidation of molecular pathomechanisms and the search for therapeutic targets of brain malformations, by employing cerebral organoids generated from patients-derived neural stem/progenitor cells
2018 - 2021 脳型ジストロフィン分子ネットワーク解析を基盤としたてんかん標的分子の同定
2015 - 2018 神経型ジストロフィンDp40の分子病態解析に基づく知的障害治療法の探索
2016 - 2017 脳型ジストロフィン分子ネットワークに着目した知的障害治療法の探索
2014 - 2015 神経型ジストロフィンDp40の分子病態解析に基づく知的障害治療法の探索
2012 - 2015 癌制御法開発のためのKRAP-IP3R相互作用機序解析とその応用
2010 - 2011 肥満・糖尿病標的としての新規代謝関連分子KRAPの分子機能解析
2009 - 2011 Establishment of KRAP-transgenic mice and elucidation of KRAP function in cancer
Takahiro Fujimoto, Tadashi Okamura, Kyoko Itoh. Extraction method combining saponin and trehalose useful for analyzing fragile intermolecular association. Biochemical and biophysical research communications. 2024. 727. 150323-150323
Hisashi Takahashi, Takahiro Fujimoto, Takeshi Yaoi, Shinji Fushiki, Kyoko Itoh. Leukemia inhibitory factor shortens primary cilia by upregulating C-C motif chemokine 2 in human neural stem/progenitor cells. Genes to cells : devoted to molecular & cellular mechanisms. 2023
Yoshihiro Taura, Takenori Tozawa, Takahiro Fujimoto, Eisuke Ichise, Tomohiro Chiyonobu, Kyoko Itoh, Tomoko Iehara. Myosin Va, a Novel Interaction Partner of STXBP1, Is Required to Transport Syntaxin1A to the Plasma Membrane. Neuroscience. 2023. 524. 256-268
Takahiro Fujimoto, Kirsten Stam, Takeshi Yaoi, Kenta Nakano, Tetsuya Arai, Tadashi Okamura, Kyoko Itoh. Dystrophin Short Product, Dp71, Interacts with AQP4 and Kir4.1 Channels in the Mouse Cerebellar Glial Cells in Contrast to Dp427 at Inhibitory Postsynapses in the Purkinje Neurons. Molecular neurobiology. 2023. 60. 7. 3664-3677
Kaori Kiso-Farnè, Takeshi Yaoi, Takahiro Fujimoto, Kyoko Itoh. Low Doses of Bisphenol A Disrupt Neuronal Differentiation of Human Neuronal Stem/Progenitor Cells. Acta histochemica et cytochemica. 2022. 55. 6. 193-202
Dystrophin short product-specific tag-insertion transgenic mouse line
(Joint Conference of the 22nd Annual Meeting of Asian Oceanian Myology Center and the 10th Annual Meeting of Japan Muscle Society (AOMC-JMS 2024) 2024)
Molecular analysis of a dystrophin gene product, Dp71, in the developing and adult mouse brains
(SCIENTIFIC SYMPOSIUM DOUBLE DEGREE MASTER PROGRAMME KYOTO PREFECTURAL UNIVERSITY OF MEDICINE AND MAASTRICHT UNIVERSITY 2021)
Dystrophin short isoform, Dp71, is regulated by phosphorylation and ubiquitin-proteasome system in neuronal cells
(11th FENS Forum of Neuroscience 2018)