2010 - 2012 Method for Pin-Point Structure Analysis of Proteins by Fluorescence-Detected CD
2010 - 2012 Protective effect of neurosteroids on developmental brains
2009 - 2011 Mechanisms for switching off of CaM-kinases and their involvement in regulation of the cellular phosphorylation balance
2011 - CaMキナーゼホスファターゼNの機能的プロセッシングとその生理的意義
2007 - CaMキナーゼ の不活性化に関わるCaMキナーゼホスファターゼファミリーの機能解析
2005 - 2006 Analysis of Signal Transduction Pathway of Syk in Breast Cancer Cells-as a comparison with that of Her2
2004 - 2005 A functional site of the essential light chain involved in the regulation of filament assembly of smooth muscle myosin.
2003 - 2005 Enzymatic study of CaM kinase phosphatase for elucidation of its biological function
2000 - 2002 Studies on Regulatory Mechanisms of CaM-dependent protein kinase phosphatases that dephosphorylate multifunctional CaM-dependent protein kinases
2000 - 2001 CaMキナーゼホスファターゼの活性制御機構と生理機能の解明に関する研究
1998 - 2001 Signal Transduction Mediated by Multifunctional Ca^<2+>/calmodulin-dependent Protein Kinases
1992 - 1994 Regulation of the Function of CNS by Ca^<2+>/calmodulin-dependent Multifunctional Protein Kinases
1989 - 1991 Structure and Function of Calmodulin-dependent Protein Kinase II and Its Physiological Significance
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Papers (108):
Osawa J, Karakawa M, Taniguchi A, Inui Y, Usuki C, Ishida A, Kameshita I, Sueyoshi N. Functional regulation of the protein phosphatase PPM1M by phosphorylation at multiple sites with Ser/Thr-Pro motifs. Arch Biochem Biophys. 2024. 753. 109887
Hisaoka, Shiho, Osawa, Jin, Kobashi, Riku, Ishida, Atsuhiko, Kameshita, Isamu, Sueyoshi, Noriyuki. Subcellular distribution of bone morphogenetic protein 2-inducible kinase (BMP2K): Regulation by liquid-liquid phase separation and nucleocytoplasmic shuttling. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2023. 649. 16-24
Kazutoshi Akizuki, Nao Shimoda, Hana Ozaki, Takeshi Yamazaki, Tetsuo Hirano, Yasuhiro Ishihara, Noriyuki Sueyoshi, Isamu Kameshita, Toshiyuki Murai, Atsuhiko Ishida. CaMK phosphatase (CaMKP/POPX2/PPM1F) inhibitors suppress the migration of human breast cancer MDA-MB-231 cells with loss of polarized morphology. Biochemical and Biophysical Research Communications. 2023. 639. 1-8
Kazutoshi Akizuki, Shun Ishikawa, Rika Obatake, Hana Ozaki, Nao Shimoda, Tatsuo Nehira, Takeshi Yamazaki, Tomoya Kinumi, Jin Osawa, Noriyuki Sueyoshi, et al. CaM kinase phosphatase (CaMKP/PPM1F/POPX2) is specifically inactivated through gallate-mediated protein carbonylation. Archives of biochemistry and biophysics. 2022. 720. 109170-109170
Kazutoshi Akizuki, Noriyuki Sueyoshi, Isamu Kameshita, Atsuhiko Ishida. Diverse physiological functions of CaMK phosphatase and studies on its inhibitors. Seikagaku. 2023. 95. 5. 676-681
In-gel protein phosphatase assay using fluorogenic substrates (Chapter 20); pp.165-172 in "Protein Gel Detection and Imaging" Kurien BT and Scofield Ed. Methods in Molecular biology 1853
2018 ISBN:9781493987443