HIROSHI KAJIYA

2018 - 2021 Immunomodulatory MSC-mediated therapies for oral mucosal lesions

2016 - 2019 Signal transduction and functional analysis of TRPM7 in the regulatory mechanism of tooth mineralization

2015 - 2018 The Mechanism of New Bone Regeneration in New Salmon DNA Scaffold

2014 - 2017 Elucidation of pathological molecular mechanism of Notch2-Hajdu Cheney Syndrome type mutation

2013 - 2016 Elucidation of a mechanism of tooth mineralization through TRP channel

2013 - 2016 Elucidation of the functional roles of Ca2+-activated potassium channels in osteoclastic bone resorption

2012 - 2015 A novel regulation of farnesyl diphosphate synthase (FDPS) on the activity of Cl- extrusion in osteoclasts

2011 - 2014 A study on the response of oral mucosa to reactive oxygen species and its application to the prevention against oral cancer.

2009 - 2012 破骨細胞酸分泌を調節する新規分子の探索とその調節機序解析

2010 - 2012 CLEC2-PLAG complex-induced oncogenic transformation in the intra-lymphatic microenvironment

2009 - 2011 Role of transient receptor potential(TRP) of Ca^<2+>-permeable cation channels in osteoclast apoptosis

2009 - 2011 Analysis of acid extrusion mechanism through new regulatory protein during bone resorption

2009 - 2011 Tissue regeneration model construcyion by nano-carbon-based molecular heater

2008 - 2010 Regulatory mechanisms of Ca^<2+> oscillations and transcription factor NFAT in osteoclastogenesis.

2007 - 2009 破骨細胞の酸分泌におけるClCN7とV-ATPaseの分子機能カップリングの解明

2007 - 2008 Functional relationships between Clcn7 and V-ATPase in osteoclastic acid secretion

2006 - 2008 Role of transient receptor potentials (TRPs) of Ca^<2+>-permeable cation channels in osteoclast differentiation

2005 - 2007 CLCN7点変異が誘発する破骨細胞Cl-輸送障害と骨大理石病の相関解析

2006 - 2007 Molecular identification and functional analysis of Na^+/Ca^<2+> exchanger (NCX) associated with osteoclastic bone resorption

2005 - 2006 CLCN7 POINT MUTANT INHIBITED Cl-EXTRUSION, RESUTLING IN OSTEOPETROSIS

2004 - 2005 The role of phosphorylation of p65 subunit on transcriptional activity of NF-κB

1998 - 1999 骨吸収時における破骨細胞プロトン放出機構のチロシンリン酸化による調節機序

1996 - 1996 破骨細胞のチロシンリン酸化による細胞内Caイオン調節機構

1992 - 1992 舌背粘膜の触刺激により出現するoff-responseが食道運動へ及ぼす効果

Study on ion transduction of osteoclast