Homma Kohei

ホンマコウヘイ | Homma Kohei

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Neuroscience - general

Research keywords (7)： iPSC , 網膜 , カルシウム , 神経分化 , Cytoskeleton , Calcium , Differentiation

Research theme for competitive and other funds (9)：

2022 - 2025 Dynamics of reactive oxygen species during retinal photoreceptor degeneration
2019 - 2022 Drug screening for Retnitis pigmentosa by using reporter knock-in human iPSCs
2016 - 2020 Minimally invasive cardiac regeneration therapy with intracoronary infusion of iPS cells
2016 - 2019 Investigation of disease mechanisms by fluorescent labeling of photoreceptor derived from retinitis pigmentosa patient-derived induced pluripotent stem cells
2014 - 2016 Analysis of developmental stage of photoreceptors derived from human iPSC

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Papers (11)：

Toshiyuki Ishii, Kohei Homma, Asuka Mano, Takumi Akagi, Yasuhide Shigematsu, Yukio Shimoda, Hiroyoshi Inoue, Yoshihiko Kakinuma, Makoto Kaneda. Novel channel-mediated choline transport in cholinergic neurons of the mouse retina. JOURNAL OF NEUROPHYSIOLOGY. 2017. 118. 4. 1952-1961
Kohei Homma, Sumiko Usui, Makoto Kaneda. Knock-in strategy at 3-end of Crx gene by CRISPR/Cas9 system shows the gene expression profiles during human photoreceptor differentiation. GENES TO CELLS. 2017. 22. 3. 250-264
Rossukon Kaewkhaw, Manju Swaroop, Kohei Homma, Jutaro Nakamura, Matthew Brooks, Koray Dogan Kaya, Vijender Chaitankar, Sam Michael, Gregory Tawa, Jizhong Zou, et al. Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2016. 57. 5. ORSFl1-ORSFl11
Rossukon Kaewkhaw, Koray Dogan Kaya, Matthew Brooks, Kohei Homma, Jizhong Zou, Vijender Chaitankar, Mahendra Rao, Anand Swaroop. Transcriptome Dynamics of Developing Photoreceptors in Three-Dimensional Retina Cultures Recapitulates Temporal Sequence of Human Cone and Rod Differentiation Revealing Cell Surface Markers and Gene Networks. STEM CELLS. 2015. 33. 12. 3504-3518
Kohei Homma, Satoshi Okamoto, Michiko Mandai, Norimoto Gotoh, Harsha K. Rajasimha, Yi-Sheng Chang, Shan Chen, Wei Li, Tiziana Cogliati, Anand Swaroop, et al. Developing Rods Transplanted into the Degenerating Retina of Crx-Knockout Mice Exhibit Neural Activity Similar to Native Photoreceptors. STEM CELLS. 2013. 31. 6. 1149-1159

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MISC (6)：

Kohei Homma, Michiko Mandai, Zi-bing Jin, Masayo Takahashi. Detection of neuronal activities of transplanted retinal cells in retinal degeneration models. NEUROSCIENCE RESEARCH. 2010. 68. E74-E74
Kohei Homma, Fumitaka Osakada, Yasuhiko Hiranni, Zi-bing Jin, Michiko Mandai, Masayo Takahashi. Measurement of neuronal function in MNU-induced retinal degeneration models by multi-electrode array system. NEUROSCIENCE RESEARCH. 2008. 61. S50-S50
Kohei Homma, Yuske Niino, Hiroto Ogawa, Kohji Hotta, Kotaro Oka. Intracellular calcium-induced modulation of actin cytoskeleton dynamics in PC12 cells. NEUROSCIENCE RESEARCH. 2006. 55. S215-S215
Homma K, Kitamura Y, Ogawa H, Oka K. 1P131 Serotonin enhances NGF-induced neurite outgrowth via 5-HT_3 receptors in PC12 cells. Seibutsu Butsuri. 2004. 44. 0. S62
本間耕平, 北村美一郎, 小川宏人, 岡浩太郎. PC12細胞におけるセロトニンによるカルシウム応答の経時変化. バイオイメージング. 2003. 12. 3. 321-322

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Patents (1)：

標的遺伝子の標識方法、ベクターシステム、細胞、及び遺伝子活性維持標的遺伝子編集キット

Professional career (2)：

Master(Science) (Keio University)
Doctor(Science) (Keio University)

Work history (7)：

2017/01 - 現在 Keio University School of Medicine Department of Ophthalmology Assistant Professor
2013/05 - 2016/12 NIPPON Medical School Department of Physiology Assistant Professor
2011/03 - 2013/04 National Eye Institute(NEI), NIH Neurobiology Neurodegeneration & Repair Lab. Visiting Fellow
2011/03 - 2013/02 JSPS Kaitoku-NIH Research fellow Research fellow
2008/04 - 2011/02 RIKEN CDB Lab for Retinal Regeneration Research fellow

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Awards (1)：

2011/03 - JSPS Kaitoku-NIH Functional studies of photoreceptors derived from embryonic and pluripotent stem cells

Association Membership(s) (10)：

IBRO , 北米神経科学大会 , 日本バイオイメージング学会 , 日本生物物理学会 , 日本神経科学大会 , International Brain Research Organization , Society for Neuroscience , The Bioimaging Society of Japan , The Biophysical Society of Japan , Japan Neuroscience Society

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