Tanaka Toshiaki

タナカトシアキ | Tanaka Toshiaki

Affiliation and department：
Job title： Assistant Professor

Research field (3)： Cell biology , Molecular biology , Developmental biology

Research keywords (6)： Cell Biology , Molecular Biology , Developmental Biology , 細胞生物学 , 分子生物学 , 発生生物学

Research theme for competitive and other funds (15)：

2023 - 2026 高悪性度大腸癌に対するがん促進性CAFを標的とした新規治療法開発の基盤研究
2018 - 2023 低造腫瘍性を示すアフリカツメガエルのゲノム情報による原因遺伝子同定とヒトへの応用
2015 - 2018 Research on fish scale collagen material technology by field fusion
2014 - 2017 A novel effect of HGF: mechanisms of irreversible arrest of cancer cell proliferation
2012 - 2015 Molecular mechanism of the non-uniform response and reversible differentiation of stem cells

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Papers (23)：

Ryuji Igarashi, Tomomi Sakai, Hideyuki Hara, Takeshi Tenno, Toshiaki Tanaka, Hidehito Tochio, Masahiro Shirakawa. Distance Determination in Proteins inside. Journal of the American Chemical Society. 2010. 132. 24. 8228-8229
Kazutaka Ushio, Tomio Hashimoto, Naomi Kitamura, Toshiaki Tanaka. Id1 Is Down-Regulated by Hepatocyte Growth Factor via ERK-Dependent and ERK-Independent Signaling Pathways, Leading to Increased Expression of p16(INK4a) in Hepatoma Cells. MOLECULAR CANCER RESEARCH. 2009. 7. 7. 1179-1188
Erika Shirako, Naoki Hirayama, Yu-ichi Tsukada, Toshiaki Tanaka, Naomi Kitamura. Up-Regulation of p21(CIP1) Expression Mediated by ERK-Dependent and -independent Pathways Contributes to Hepatocyte Growth Factor-induced Inhibition of HepG2 Hepatoma Cell Proliferation. JOURNAL OF CELLULAR BIOCHEMISTRY. 2008. 104. 1. 176-188
Asuka Kondo, Naoki Hirayama, Yasuko Sugito, Michihiro Shono, Toshiaki Tanaka, Naomi Kitamura. Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation. JOURNAL OF BIOLOGICAL CHEMISTRY. 2008. 283. 3. 1428-1436
Tomorni Sakai, Hidehito Tochio, Kosuke Inomata, Yoshiyuki Sasaki, Takeshi Tenno, Toshiaki Tanaka, Tetsuro Kokubo, Hidekazu Hiroaki, Masahiro Shirakawa. Fluoroscopic assessment of protein leakage during Xenopus oocytes in-cell NMR experiment by co-injected EGFP. ANALYTICAL BIOCHEMISTRY. 2007. 371. 2. 247-249

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Books (3)：

CDK inhibitory Proteins.
In: H. Maruta ed. Tumor Suppresing Virus, Genes, and Drugs: Innovative Cancer Therapy Approaches. Academic Press, San Diego 2002
トランスジェニックガエル作成法
遺伝子医学別冊「図で観る発生・再生医学実験マニュアル」 2002
Cdk インヒビターp27 の分解と癌
実験医学増刊 2001

Works (8)：

ツメガエル中期胞胚遷移 (MBT) における cyclin E 分解とエピジェネティクス制御の関係の解析
2009 -
肝細胞増殖因子 HGF による肝癌細胞株 HepG2 の G1 期停止に対する non-coding RNA の機能の研究
2007 -
肝細胞増殖因子による肝癌細胞株HepG2における p16INK4a 発現の分子制御
2002 - 2005
非小胞性肺癌におけるインターフェロンλ (IL-28A, 29) による細胞増殖抑制の分子機構とその応用
2005 -
ツメガエル未受精卵内におけるNMRによるin vivo タンパク質構造変化の検出
2005 -

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Education (3)：

- 1994 Kyoto University Graduate School, Division of Natural Science
- 1994 京都大学大学院理学研究科生物物理学専攻
- 1989 Nagoya University School of Science

Professional career (1)：

Ph.D (Kyoto University)

Work history (8)：

2007 - -:
2007 - -:東京工業大学大学院生命理工学研究科助教
1994 - 2002 :Nara Institute of Science and Technology Graduate School of Biological Sciences Assistant Professor
1994 - 2002 :奈良先端科学技術大学院大学バイオサイエンス研究科助手
2002 - -:Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Assistant Professor

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Committee career (1)：

2005 - 2006 学生実習ワーキンググループ委員(2005-2006 年度)

Association Membership(s) (8)：

The American Society for Biochemistry and Molecular Biology (ASBMB) , Japan society for cell biology , The Japanese Cancer Association , The molecular biology society of Japan , The American Society for Biochemistry and Molecular Biology (ASBMB) , 日本細胞生物学会 , 日本癌学会 , 日本分子生物学会

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