Fukushima Tsuyoshi

フクシマツヨシ | Fukushima Tsuyoshi

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.med.miyazaki-u.ac.jp/patho2/index.html

Research field (4)： Molecular biology , Human pathology , Neurosurgery , Experimental pathology

Research keywords (1)： Life science

Research theme for competitive and other funds (12)：

2017 - 現在 Multifaceted approach for understanding of malignant phenotype of glioblastoma
2021 - 2022 脳腫瘍の発生・増殖・浸潤に関する分子病理学的解析
2019 - 2020 脳腫瘍の発生・増殖・浸潤に関する分子病理学的解析
2016 - 2017 脳腫瘍の浸潤・増殖を制御する分子機構の解析
2012 - 2016 Regulation of protease activities on the epithelial cell surface and its significance in epithelial disorders.

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Papers (86)：

木脇拓道, 川口真紀子, 片岡寛章, 福島剛. LRP11は肺腺癌の予後不良と関連する(Low-density lipoprotein receptor related protein 11(LRP11) contributes to poor prognosis in lung adenocarcinoma). 日本癌学会総会記事. 2023. 82回. 1397-1397
Makiko Kawaguchi, Hiroaki Kataoka, Takumi Kiwaki, Weiting Liang, Sayaka Nagata, Kazuo Kitamura, Tsuyoshi Fukushima. Adrenomedullin alleviates mucosal injury in experimental colitis and increases claudin-4 expression in the colonic epithelium. FEBS Open Bio. 2023
川口真紀子, 木脇拓道, 福島剛, 片岡寛章. マトリプターゼ欠損は大腸発癌を誘発し、Claudin-7の局在異常をもたらす(Loss of matriptase leads to colorectal carcinogenesis and causes abnormal localization of Claudin-7 in tumor cells). 日本癌学会総会記事. 2022. 81回. P-2088
福島剛, 川口真紀子, 木脇拓道, 片岡寛章. MGMTメチル化以外の膠芽腫の抗がん剤耐性機序(Mechanism of chemoresistance to temozolomide besides MGMT status in glioblastoma cells). 日本癌学会総会記事. 2022. 81回. P-2303
Fumiki Yamashita, Takashi Kaieda, Takeshi Shimomura, Makiko Kawaguchi, Chen-Yong Lin, Michael D Johnson, Hiroyuki Tanaka, Takumi Kiwaki, Tsuyoshi Fukushima, Hiroaki Kataoka. Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor-1. The FEBS Journal. 2022. 289. 12. 3422-3439

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MISC (18)：

Tsuyoshi Fukushima, Shuichiro Uchiyama, Hiroyuki Tanaka, Hiroaki Kataoka. Hepatocyte growth factor activator; a proteinase linking tissue injury with repair. International Journal of Molecular Sciences. 2018. 19. 11. 3435-3435
Kataoka H, Kawaguchi M, Fukushima T, Shimomura T. Hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2): emerging key players in epithelial integrity and cancer. Pathology International. 2018. 68. 3. 145-158
赤木真由美, 西村豊樹, 池田俊郎, 布井博幸, 梅北佳子, 福島剛, 田中弘之, 秋山裕, 片岡寛章. 劇症肝障害を呈したインフルエンザ脳症の一剖検例. 日本病理学会会誌. 2017. 106. 1. 417-417
福島剛, 横山貴裕, 山下真治, 横上聖貴, 竹島秀雄, 梅北佳子, 秋山裕, 赤木真由美, 田中弘之, 片岡寛章. 肥胖細胞と退形成性変化が著明であった悪性星芽腫の一例. 日本病理学会会誌. 2017. 106. 1
Tsuyoshi Fukushima, Jingjia Ye, Makiko Kawaguchi, Yukihiro Haruyama, Ai Kanemaru, Koji Yamamoto, Hiroaki Kataoka. Silencing of membrane-bound serine protease inhibitor, HAI-1, enhances metastatic capability of pancreatic cancer cells in mouse models. CLINICAL & EXPERIMENTAL METASTASIS. 2015. 32. 3. 202-202

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Books (2)：

Chaptor 5; Alkylating Agents and Treatment of Gliomas. In: Yildiz Dincer eds. Alkylating Agents as Environmental Carcinogen and Chemotherapy Agents
Nova Science Publishers, Inc. 2013 ISBN:9781626184879
Chapter 19: Insulin-Like Growth Factor Binding Protein-2: A Possible Regulator of Invasive Growth in Glioblastoma. In: Miklos Grami eds. Molecular Targets of CNS Tumors
InTech 2011 ISBN:9789533077369

Lectures and oral presentations (147)：

An autopsy case of brain tumor accompanied by systemic metastasis: a difficulty in discrimination between glioblastoma and small cell carcinoma
(The 40th Annual Meeting of Japanese Human Cell Society 2022)
Mechanism of chemoresistance to temozolomide besides MGMT status in glioblastoma cells
(第81回日本癌学会学術総会 2022)
A case of brain tumor accompanied by systemic metastasis with bone marrow carcinomatosis
(The 31st Meeting of the Japanese Association for Metastasis Research 2022)
AT/RT 6例の臨床病理学的検討
(第40回日本脳腫瘍病理学会 2022)
Exploratory research for novel functional genes in glioblastoma
(The 39th Annual Meeting of Japan Human Cell Society 2021)

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Education (2)：

- 2007 University of Miyazaki Graduate School, Division of Medical Sciences
- 1996 Miyazaki Medical College Faculty of Medicine

Work history (10)：

2021/07 - 現在 University of Miyazaki Faculty of Medicine School of Medicine Department of Pathology, Oncopathology and Regenerative Biology Associate Professor
2007/08 - 2021/06 University of Miyazaki Faculty of Medicine School of Medicine Department of Pathology, Oncopathology and Regenerative Biology Assistant Professor
2007/04/01 - 2007/07/31 University of Miyazaki Faculty of Madicine School of Madicine Pathology course tumor and reproduction condition study field Assistant Professor
2003/04/01 - 2007/07/31 University of Miyazaki Faculty of Madicine School of Madicine Pathology course tumor and reproduction condition study field Graduate student(doctorate program)
2002/04/01 - 2003/03/31 医療法人青雲会青雲病院医師(脳神経外科)

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Committee career (11)：

2023/07 - 現在 The Japan ese Association for Cancer Metastasis Research Director
2021/05 - 現在日本脳腫瘍病理学会評議員
2021/04 - 現在日本病理学会学術評議員
2017/04/01 - 現在日本ヒト細胞学会評議員
2017/04 - 現在日本ヒト細胞学会理事

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Awards (2)：

2013/08/11 - 日本ヒト細胞学会第31回日本ヒト細胞学会学術集会ポスター発表賞
2012/07/12 - 日本がん転移学会日本がん転移学会研究奨励賞

Association Membership(s) (13)：

International Academy of Pathology, Japanese Division , The Japanese Society of Clinical Cytology , The Japanese Association for Metastasis Research , The Japanese Human Cell Society , American Association for Cancer Research , The Japanese Society of Pathology , Japanese Cancer Association , Japan Neurosurgical Society , The Japan Society for Clinical Laboratory Automation , Japanese Congress of Neurological Surgeons , The Molecular Biology Society of Japan , 日本脳腫瘍病理学会 , The Japan Society of Molecular Neurosurgery

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