Kosaka Megumi

コサカメグミ | Kosaka Megumi

Affiliation and department：
Job title： Research Associate

Research field (1)： Structural biochemistry

Research keywords (6)：環境電磁工学 , X線構造解析 , 蛋白質工学 , Electromagnetic Compatibility , Structural Analysis , Protein Engineering

MISC (69)：

Tadayoshi Kanao, Megumi Kosaka, Kyoya Yoshida, Hisayuki Nakayama, Taro Tamada, Ryota Kuroki, Hidenori Yamada, Jun Takada, Kazuo Kamimura. Crystallization and preliminary X-ray diffraction analysis of tetrathionate hydrolase from Acidithiobacillus ferrooxidans. Acta crystallographica. Section F, Structural biology and crystallization communications. 2013. 69. Pt 6. 692-4
Hitoshi Murata, Junichiro Futami, Midori Kitazoe, Takayuki Yonehara, Hidetaka Nakanishi, Megumi Kosaka, Hiroko Tada, Masakiyo Sakaguchi, Yasuyuki Yagi, Masaharu Seno, et al. Intracellular delivery of glutathione S-transferase-fused proteins into mammalian cells by polyethylenimine-glutathione conjugates. JOURNAL OF BIOCHEMISTRY. 2008. 144. 4. 447-455
Hitoshi Murata, Junichiro Futami, Midori Kitazoe, Megumi Kosaka, Hiroko Tada, Masaharu Seno, Hidenori Yamada. Transient cell proliferation with polyethylenimine-cationized N-terminal domain of simian virus 40 large T-antigen. JOURNAL OF BIOSCIENCE AND BIOENGINEERING. 2008. 105. 1. 34-38
Hidenori Yamada, Taro Tamada, Megumi Kosaka, Kohei Miyata, Shinya Fujiki, Masaru Tano, Masayuki Moriya, Mamoru Yamanishi, Eijiro Honjo, Hiroko Tada, et al. 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: Crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines. PROTEIN SCIENCE. 2007. 16. 7. 1389-1397
H Murata, M Sakaguchi, J Futami, M Kitazoe, T Maeda, H Doura, M Kosaka, H Tada, M Seno, N Huh, et al. Denatured and reversibly cationized p53 readily enters cells and simultaneously folds to the functional protein in the cells. BIOCHEMISTRY. 2006. 45. 19. 6124-6132

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Lectures and oral presentations (65)：

疎水性残基の導入が難結晶性タンパク質の結晶化に与える影響
(ConBio2017 2017年度生命科学系学会合同年次大会 2017)
タンパク質のパッキングをコントロールする疎水性残基導入
(平成29年度日本結晶学会年会 2017)
無機硫黄化合物加水分解酵素の結晶構造
(第17回日本蛋白質科学会年会 2017)
Hydrophobic residue introduction affect crystallization of the hard to crystallize proteins.
(2017)
Crystal structure of tetrathionate hydrolase from Acidithiobacillus ferrooxidans.
(2017)

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Professional career (1)：

理学士 (島根大学)

Work history (2)：

2004 - - 岡山大学自然生命科学研究支援センター助手
2004 - - Research Associate,Department of Instrumental Analysis Advanced Science Research Center,Advanced Science Research Center,Okayama University

Committee career (1)：

2017 - 2019 2017- 日本分析化学会有機微量分析研究懇談会標準試料検定小委員会標準試料検定小委員会委員(2017-2019)

Association Membership(s) (3)：

日本蛋白質科学会 , 日本分子生物学会 , 電子情報通信学会

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