2021 - 2024 Establishment of rapid functional diagnosis of genome information and its application to cancer precision medicine
2021 - 2024 非小細胞肺がんのがん間質における低酸素応答の解析とがん免疫治療への応用
2019 - 2022 Development of liquid biopsy for rapid molecular pathological diagnosis of highly malignant tumors and its application to precision medicine
2019 - 2022 Identification of biomarker and therapeutic target for lung cancer
2017 - 2021 Elucidation of the onset mechanism of osteoporosis and osteoarthritis caused by stress on mesenchymal stem cells
2017 - 2021 Elucidation of resistant mechanism for immunotherapy mediated by MAPK signal-driven chemokine suppression
2016 - 2021 コホート・生体試料支援プラットフォーム
2016 - 2019 Establishment of pharmaceutical care for improving QOL in patient receiving palliative care
2016 - 2019 Clinical application of high sensitive biomarker and therapeutic target for lung cancer
2016 - 2019 Development of cancer immunotherapy targeting for the immune responses in tumor stroma in non-small cell lung cancer
2015 - 2018 Development of molecular pathological diagnostics for refractory cancer
2015 - 2018 Molecular analysis of carcinogenesis based on genetic and environmental factors towards the development of new cancer therapeutics
2010 - 2016 Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
2012 - 2015 Development of integrated molecular pathological diagnostic systems for cancer
2012 - 2015 Identification of new biomarkers and therapeutic targets for lung cancer
2011 - 2013 Characterization of genetic factors that modify the risk of cancer and could be useful for the development of new cancer prevantion drugs
2010 - 2011 Identification of biomarker and therapeutic target for lung cancer
2009 - 2011 Establishment of molecular pathological diagnosis of lung and esophageal cancers : Detection of precancerous region and early stage cancer and evaluation of their malignant level.
2004 - 2006 Characterization of novel therapeutic target oncogenes using gene-targeted somatic cells
癌の個別化医療に向けた統合的分子病態診断システムの開発
癌の薬剤感受性と転移機構の解明
癌の新規分子標的薬剤と診断バイオマーカーの開発
新規癌関連遺伝子の同定と機能解析
Integrated molecular staging of cancer for personalized medicine
Analysis of the mechanisms of chemosensitivity and metastases of cancer
Identification of novel therapeutic targets and diagnostic biomarkers for cancer
Identification of novel cancer-related genes
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Papers (182):
Regina Wachuka Mbugua, Atsushi Takano, Bayarbat Tsevegjav, Tomoyuki Yokose, Toshinari Yamashita, Yohei Miyagi, Yataro Daigo. Characterization of KIF20B as a novel prognostic biomarker and therapeutic target for breast cancer. International journal of oncology. 2024. 64. 4
Kosuke Natsume, Juanjuan Ye, Yuri Mukai, Keiko Yamakawa, Misa Tanimoto, Hiroyuki Ito, Yohei Miyagi, Yataro Daigo, Mariko Muto-Ishizuka, Kyuichi Kadota, et al. Discrepancies Between Morphological and Immunohistochemical Classifications Are Associated With Prognoses and Subtypes of Lung Cancer. Anticancer research. 2024. 44. 2. 711-722
Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, Yataro Daigo, Syuzo Kaneko, Takahisa Kawaguchi, Hideo Kunitoh, Shingo Matsumoto, Hidehito Horinouchi, Akiteru Goto, et al. Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses. Cancer communications (London, England). 2023
Yoshihiro Mezawa, Tingwei Wang, Yataro Daigo, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Liying Yang, Reo Maruyama, Hiroyuki Seimiya, et al. Glutamine deficiency drives transforming growth factor-β signaling activation that gives rise to myofibroblastic carcinoma-associated fibroblasts. Cancer science. 2023
Takuya Hiratsuka, Shinji Ito, Rika Sakai, Tomoyuki Yokose, Tatsuya Endo, Yataro Daigo, Yohei Miyagi, Tatsuaki Tsuruyama. Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins. Clinical proteomics. 2023. 20. 1. 36-36
村田 聡, 三宅 亨, 小島 正継, 谷 総一郎, 寺本 晃治, 住本 秀敏, 森 治樹, 竹林 克士, 貝田 佐知子, 前平 博充, et al. 症例報告からPrecision Medicineへ-第1部-(Effective response to immunotherapy in far advanced colon cancer harboring somatic POLE P286R mutation leading to hypermutation with microsatellite stable phenotype: a case study). 日本癌治療学会学術集会抄録集. 2023. 61回. ICCJ1-6
ンポガ・レジナ, 高野 淳, ツェペグジヤブ・バヤルバット, 宮城 洋平, 醍醐 弥太郎. 乳がんの新規バイオマーカー・治療標的分子URST8の機能解析(Identification of URST8 as a novel prognostic biomarker and therapeutic target for breast cancer). 日本癌学会総会記事. 2023. 82回. 39-39
ツェベグジヤブ・バヤルバット, 高野 淳, 吉武 義恭, 篠原 正徳, 醍醐 弥太郎. 口腔癌の新規バイオマーカー、分子標的候補URST7の解析(Molecular characterization of URST7 as a potential prognostic biomarker and therapeutic target for oral cancer). 日本癌学会総会記事. 2023. 82回. 545-545