Nakano Takayoshi

2022 - 2025 レーザ積層造形法による粉末とレーザの重畳効果を利用した高機能性発現材料の創製

2020 - 2024 Novel therapeutic strategies for bone metastasis; Targeting the microstructural alteration in metastasized bone

2019 - 2023 骨劣化を生じない新骨機能化インプラントロジー

2018 - 2023 "Materials Science of Anisotropy" for induction of bone tissue anisotropy

2020 - 2022 Development of a new scientific principle of anisotropic bone matrix science based on materials engineering

2018 - 2022 Molecular targeted therapy for MRONJ

2019 - 2021 Establishment of a new bone regeneration method that enables rapid recovery of bone mechanical function

2018 - 2020 Control of osteoblast arrangement by surface topography induced by plastic deformation

2017 - 2020 Development of a novel scientific principle of "Biological Materials Science of Bone"

2018 - 2019 骨自発的・人為的アプローチによる骨配向化機構の解明と制御

2016 - 2019 Clarification of self-adjusting capacity of strength in bone focusing on osteocytes

2016 - 2019 Development of toughness and creep strength of B added transition metal disilicides with lamellar structure

2015 - 2019 Treatment for promoting early healing of bone fracture using the combination of anti-osteoporosis drugs

2016 - 2018 Consideration of design principle for creating implant that does not cause strain shielding on bone based on bone matrix orientation

2015 - 2018 Development of the noble biodegradable implant composed of multi-phase intermetallic compounds, which spontaneously makes porous structure in human body

2015 - 2018 Establishment of micro-endodontic model in small animal and development of root canal treatment tschnique and root canal treatment drugs

2013 - 2018 Induction of anisotropic bone tissues based on combination of materials science and bone biology

2015 - 2017 Cellular mechanisms underlying anisotropic bone matrix construction

2015 - 2017 Development of biocompatible piezoelectric materials as an "active biomaterial"

2015 - 2017 Development of bone function-mimetic metallic implants that is recognized as "bone" itself

2015 - 2017 Optimization of implant design which controls bone quality under loaded conditions

2013 - 2017 Nanomechanics of jaw bone confirmed preferential alignment of biological apatite

2014 - 2016 Clarification of anomalous fatigue softening in biomedical Ti-Nb alloys

2013 - 2016 Control of BAp orientatio in mandible with the masticatory disturbance using gene-deleted pathological mice.

2013 - 2016 Bone mechanical functionalization by control of bone quality using stress field

2013 - 2015 Prototyping of composite products with bone-mimetic mechanical functions based on novel functionalization concept

2012 - 2015 Development of new biodegradable implant materials based on the intermetallic compounds

2012 - 2015 Development of experimental pathologic refractory periapical periodontitis model and investigation of its chemical supplemental methods

2013 - 2014 骨配向化機構に基づく骨代替生体材料の創製

2011 - 2014 Development of adhesive resins with the function to promote tissue regeneration by release of FGF-2

2010 - 2014 Clarification of implant loading condition on the basis of nanometer level structural analyses

2009 - 2013 異方性の材料科学に基づく骨配向化誘導

2011 - 2012 Clarification of the origin of fatigue softening and one variant ωphase in binary Ti-Nb based biomaterial alloys

2009 - 2011 Elucidation of the mechanism of biomineralization with acidic phosphoprotein from molecular evolution studies

2009 - 2011 Analysis of change in mandible bone microstructure induced by masticatory malfunction from a viewpoint of crystallography

2009 - 2011 The wave propagation in the bone surrounding dental implants using the thinning model of trabecular bone

2008 - 2010 生体内外環境制御による生体アパタイト配向化メカニズムの解明

2007 - 2010 The pursuit of conservative dental treatment design in a new era by diverse utilization of an antibacterial monomer

2009 - 2009 骨配向性を考慮した新規概念からなるバイオマテリアルの設計・開発

2009 - 2009 骨類似機能を発揮するパウダー/ソリッド三次元造形複合体の創製

2007 - 2008 Mechanism for formation of preferential alignment in bone microstructure

2007 - 2008 Analysis of bone mass and quality associated with biomechanical property in glucocorticoid osteopathy

2007 - 2008 マテリアル・ボーンバイオロジーの構築

2005 - 2008 Development of new bone method for evaluating pathological or regenerated hard tissues and bone design for biomedical application

2006 - 2007 A analysis of bone quality of growing rat mandible by a novel evaluation system

2005 - 2007 Produdion of transgenic mice and functional analysis ofosteaytesusingcis-regulatory regions

2006 - 2006 アトミスティック・メタラジーによる第3世代金属間化合物研究への新展開

2005 - 2006 強磁場を用いた骨組織の早期再生技術の開発と材料工学的解析

2003 - 2004 Functional Analysis of Dentin Matrix Protein 1 (DMP1) and Regulation Analysis of their Expression during Fracture Healing.

2003 - 2004 自己再生能力を持つ配向性ナノアパタイト材料の開発

2002 - 2004 Observation of lattice defects, deformation behavior in duplex alloys and evaluation of their lifetime using magnetic properties.

2002 - 2004 Development of new endodontic materials by changing microstructure of hydroxyapatite ceramics

2002 - 2003 再生骨のための配向性制御アパタイトの創製

2001 - 2002 Microstructure and plastic deformation in (C11_b/C40) duplex-phase silicide with a sigle set of lamellae

2000 - 2001 結晶性,形態制御アパタイトによる生体硬組織再生

1999 - 2001 Control of micro-structure and phase interface for concurrent design of multi-functional materials.

1999 - 2000 Clarification of processes for ordering and precipitation of long-period superstructures in Al-rich TiAl rapidly solidified ribbons

1998 - 2000 Development of NbSi_2-Based Duplex Silicides for Turbine Blade Operating at Ultra High-Temperature

1998 - 1999 磁気異方性によるNi_3Feの疲労微細組織観察

1997 - 1999 The stability of microstructure and the fatigue deformation mechanism of duplex aluminides containing fine precipitates under cyclic loading.

1999 - 配向性HAp結晶を用いた再生医工学技術の確立

1997 - 1998 Al-rich TiAl単結晶の変形挙動に及ぼすAl_5Ti_3型超格子規則相の寄与

1997 - 生体内硬組織におけるHAp結晶の配向性

1997 - Texture in biological hard tissues

1996 - 1996 交番変形応力下でのTi_3Al単結晶の疲労挙動の解明

1995 - 1996 Plastic Anisotropy and Fatigue Fracture Mechanism of TiAl Alloys under Cyclic Loading.

1995 - 1996 Development of Testing Machine for Mechanical Properties at Ultra High Temperature using Impulse Electron Irradiation

1995 - 1995 定応力制御下でのTiAl-PST結晶の疲労特性の解明

1995 - Development of biomaterials containing oriented HAp for regeneration hard tissues

1994 - 1994 Ti_3Al単結晶の破壊挙動に及ぼす塑性異方性の影響

1994 - 金属間化合物単結晶の疲労・破壊特性

1994 - Fatigue Behaviour of Single Crystals of Intermetallics.

1993 - 1993 AEを用いた方向制御層状組織を有するTiAiの破壊に関する研究

1992 - 耐火金属シリサイド単結晶の変形挙動

1992 - Plastic Behaviour of Refractory Silicide Single Crystals

HAp結晶子配向性の解析(生体, 再生硬組織との)

シリサイド単結晶の異常強化機構

Al-rich TiAlの組織と変形機構

Analysis of HAp crystallite orientation in hard tissues.

Anomalous strengthening mechanism of silicide single crystals

Microstructure and deformation mechanism in Al-rich TiAl