Hiroshi Takuma

Research field (2)： Neuroscience - general , Neurology

Research theme for competitive and other funds (5)：

2013 - 2015 筋萎縮性側索硬化症原因遺伝子とRNA編集酵素との連関カスケードに基づく治療戦略
2009 - 2011 孤発性筋萎縮側索硬化症における運動ニューロン死へのRNA編集酵素と多因子の関与
2007 - 2008 孤発性筋萎縮性側索硬化症におけるRNA編集新規基質の探索とバイオマーカーの開発
2004 - 2005 Mechanism for the regulation of the expression of tau-isoforms in demented neurodegenerative disease
2001 - 2002 Contribution of RNA-editing in the sporadic Alzheimer's disease

Papers (16)：

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Books (9)：

ブレインサイエンス・レビュー 2014
クバプロ 2014
認知症治療薬開発の現状;第7回ワクチン療法
Cognition and Dementia 2012
症状からみた歩行障害と専門医への紹介のタイミング 1.筋力低下による歩行障害
歩行障害ハンドブック; 三木隆巳,嶋田裕之編,真興交易 2009
Molecular changes of AMPA receptor subunits in ALS spinal cord
Molecular Mechanism and Therapeutics of Amyotrophic Lateral Sclerosis. Elsevier Science B.V., Amsterdam 2001
タウとコンフォメーション
神経難病の分子機構-タンパク質のコンフォメーション異常による疾患(石浦章一編)、シュプリンガー・フェアラーク東京 2000

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Lectures and oral presentations (53)：

Altered CpG methylation in sporadic Alzheimer’s disease is associated with APP and MAPT dysregulation
(Society for Neuroscience 43th Annual Meeting 2013)
TDP-43 aggregation produced by In utero electroporation and its properties in the mouse motor neurons
(Society for Neuroscience 43th Annual Meeting 2013)
Two japanese cases of adult onset myopathic form of glutaric acidemia type II
(12th International Congress of Inborn errors of Metablism 2013)
抗 MuSK 抗体陽性重症筋無力症の臨床的検討
(第54回日本神経学会総会 2013)
成人期に発症した「骨格筋型」グルタル酸尿症2型の2例
(第54回日本先天代謝異常学会総会 2012)

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Education (3)：

1994 - 1998 The University of Tokyo Graduate School, Division of Medical Sciences
1985 - 1991 Osaka City University Faculty of Medicine
1980 - 1985 Osaka University Faculty of Engineering Science

Professional career (1)：

Work history (4)：

2007/01/01 - University of Tsukuba
2005/07/01 - 2006/12/31 Max-Planck Institute for Medical Research Scientist
2000/04/01 - 2005/06/30 Osaka City University Department of Neuroscience, Graduate School of Medicine Assistant Professor
University of Tsukuba Faculty of Medicine Assistant Professor

Committee career (1)：

Awards (2)：

Association Membership(s) (4)：

Society for Neuroscience , JAPAN SOCIETY FOR DEMENTIA RESEARCH , THE JANPANESE SOCIETY OF INTERNAL MEDICINE , JAPANESE SOCIETY OF NEUROLOGY

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