Haseba Takeshi

ハセバタケシ | Haseba Takeshi

Affiliation and department：
Job title： Associate Professor

Research field (6)： Pathobiochemistry , Laboratory animal science , Molecular biochemistry , Forensic medicine , Molecular biology , Functional biochemistry

Research keywords (8)： Synthetic anthropology , DNA identificatio and diagnosis , Lifescience of alcohol , 分子生物学 , 法医学 , Molecular Biology , Functional biochemistry , Legal Medicine

Research theme for competitive and other funds (6)：

DNA多型と個人識別,血縁関係
溶液の構造と生物学的反応性との関係
アルコ-ルの代謝機構と細胞および生体への影響
DNA polymorphism on personal identification or blood relationship
Solution structure and biological reactivity

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Papers (71)：

HASEBA Takeshi. Effects of ALDH2 genetic polymorphism on the adaptive change in alcohol metabolism due to continuous moderate alcohol consumption in humans. 2015
Hyon-Seung Yi, Young-Sun Lee, Jin-Seok Byun, Wonhyo Seo, Jong-Min Jeong, Ogyi Park, Gregg Duester, Takeshi Haseba, Sun Chang Kim, Keun-Gyu Park, et al. Alcohol Dehydrogenase III Exacerbates Liver Fibrosis by Enhancing Stellate Cell Activation and Suppressing Natural Killer Cells in Mice. HEPATOLOGY. 2014. 60. 3. 1044-1053
HASEBA Takeshi. Molecular evidence of non-ADH pathway in alcohol metabolism and Class III alcohol dehydrogenase (ADH3 evidence of non-ADH pathway in alcohol metabolism and Class III alcohol dehydrogenase (ADH3). 2014. 49. 3. 159-168
HASEBA Takeshi. Alcohol metabolism in healthy subjects on daily life. Psychiatry. 2014. 24. 5. 501-507
HASEBA Takeshi. Dose effect of alcohol on sex differences in blood alcohol metabolism-cases where healthy subjects with ALDH2*1/*1 genotype drunk beer with meal-. Jpn. J. Alcohol & Drug Dependence. 2013. 48. 3. 187-197

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MISC (50)：

In vivo contribution of Class 3 alcohol dehydrogenase (ADH3)to alcohol metabolism through activation by cytoplasmic solution hydrophobicity. Biochim. Biophys. Acta. 2006
Maturation of whisky delays ethanol metabolism to diminish metabolic toxicity with increasing liver alcohol dehydrogenase inhibition by non-volatile congeners. Alcoholism:Clin.Exp.Res. 2006
ウイスキーの熟成は酩酊およびアルコール代謝にどのような影響を及ぼすか. アルコールと生物医学. 2005. 25、65-71
アルコール医学と法的諸問題. 賠償科学. 2005. No.32、30-39
The contribution of the dynamic behavior of a water molecule to the amyloid formation of yeast alcohol dehydrogenase. J. Mol. Liq. 2004. 109, 45-52

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Lectures and oral presentations (6)：

Effects of alcohol on the body and traffic accidents due to drinking
(Invited lecture from Zhejiang Police College in China 2011)
Alcohol: metabolism and its effects on the body
(Research seminer of Asahi beer Co., Ltd. 2011)
Alcohol dehydrogenases-their biological and medical roles-.
(Vietnam Academy Science and Thechnology, Institute of Tropical Biology 2009)
ウイスキーの熟成がアルコール代謝および酩酊に及ぼす影響とその機序について
(アサヒビール株式会社研究セミナー 2004)
アルコールの医学と法的諸問題
(賠償科学会第43回研究会 2003)

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Works (13)：

Role of Class III ADH (ADH 3), a new alcohol metabolizing enzyme, on biosensitivities for alcohol
HASEBA Takeshi 2008 - 2011
酒類の熟成が生体に及ぼす影響
2003 -
Effects of whisky ageing on biomedical reactivity of alcohol
2003 -
文部省科学研究補助金基盤研究B(2)細胞防御系ハウスキーピング酵素Class(]G0003[)ADHのアルコール代謝における役割-ノックアウトマウスを用いるin vivo実験と酵素の活性調節機構解明のためのin vitro実験
1999 - 2001
Role of ClassIII alcohol dehydrogenase(ADH3), a housekeeping enzyme for cytotoxicity, in alcohol metabolism
1999 - 2001

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Education (4)：

1974 - 1976 東京教育大学大学院農学研究科農芸化学
- 1976 Tokyo University of Education Graduate School, Division of Agriculture Food biochemistry
1970 - 1974 Tokyo University of Agriculture and Technology Faculty of Agriculture
- 1974 Tokyo University of Agriculture and Technology Faculty of Agriculture

Professional career (2)：

Master of Agriculture
Dr. of Medical Science (Nippon Medical School)

Work history (14)：

2014/04 - 現在財団法人博慈会高等看護専門学校非常勤講師(保健医療論)
2014/04 - 現在 Nippon Medical School, Legal Medicine Associate Professor
1999/04 - 現在戸田中央高等看護専門学校非常勤講師(人間生物学)
2010/04 - 2014/03 Nippon Medical School Legal Medicine Associate Professor
1992/04 - 2010/03 - 日本医科大学 (法医学) 講師

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Committee career (4)：

2010/04 - 現在総合人間学会理事 (2014年から広報委員長)
1995 - 現在日本法医学会評議員
1984 - 現在日本アルコール医学会評議員(プログラム委員:2012~2014年)
1984 - Jpn. Society of Legal Medicine, Jpn.Medical Society of Alcohol & Drud Studies, Jpn. Biochemical Society,Jpn. Society of Nutrition and Food Science, International Society of Biomedical Research on Alcoholism, Concilor (Jpn. Society of Legal Medicine and Jpn.Medical Society of Alcohol & Drud Studies)

Association Membership(s) (12)：

JAPAN ASSOCIATION OF SYNTHETIC ANTHROPOLOGY , 日本栄養・食糧学会 , DNA多型学会 , International Society of Biomedical Research on Alcoholism (ISBRA) , 日本生化学会 , 日本アルコール医学会 , 日本法医学会 , International Society of Biomedical Research on Alcoholism , Jpn. Society of Nutrition and Food Science , Jpn. Biochemical Society , Jpn.Medical Society of Alcohol & Drud Studies , Jpn. Society of Legal Medicine

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