Umezu Tomohiro

ウメヅトモヒロ | Umezu Tomohiro

Affiliation and department：
Job title：講師(特任)

Research field (2)： Tumor biology , Developmental biology

Research keywords (2)：エクソソーム , miRNA

Research theme for competitive and other funds (13)：

2021 - 2024 Analysis of the mechanism of ncRNA-mediated carcinogenesis using the DICER1 syndrome model
2021 - 2024 非腫瘍組織における加齢性遺伝的変化の解析-がん間質発生機序との関連を探る-
2018 - 2021 Secretome analysis of tumor stroma involved in the process of cancer progression
2016 - 2019 Novel therapies development of multiple myeloma using engineering exosomes derived from bone marrow stromal cells
2015 - 2018 Development of novel diagnostics for hematological malignancy on basis of the exosome analysis

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Papers (72)：

Masaki Asakage, Yoshihiko Usui, Hiroyuki Komatsu, Kazuichi Maruyama, Naoya Nezu, Hiroyuki Shimizu, Kinya Tsubota, Naoyuki Yamakawa, Tomohiro Umezu, Masakatsu Takanashi, et al. Comprehensive microRNA analyses using vitreous humor of ocular sarcoidosis. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 2024
Tomohiro Umezu, Tomoya Mori, Hidenori Toyoda, Kohsuke Kanekura, Akihiro Tamori, Takahiro Ochiya, Masahiko Kuroda, Tatsuya Akutsu, Yoshiki Murakami. Analysis of Carcinogenic Involvement of MicroRNA Pattern in Peripheral Non-Cancerous Tissues and Chronic Viral Liver Injury. International journal of molecular sciences. 2024. 25. 14
Tomohiro Umezu, Shogo Tanaka, Shoji Kubo, Masaru Enomoto, Akihiro Tamori, Takahiro Ochiya, Y.-H. Taguchi, Masahiko Kuroda, Yoshiki Murakami. Characterization of circulating miRNAs in the treatment of primary liver tumors. Cancer Reports. 2023
梅津知宏, 工藤勇人, 嶋田善久, 大平達夫, 村上善基, 池田徳彦, 黒田雅彦. 肺癌患者由来cfDNAから検出されたde novo mutational signatureの同定と生物学的意義の解明(Identification and biological significance of de novo mutational signatures in cfDNA derived from lung cancer patients). 日本癌学会総会記事. 2023. 82回. 213-213
Yuma Furusaka, Shinya Inoue, Izuru Mizoguchi, Hideaki Hasegawa, Yasuhiro Katahira, Aruma Watanabe, Eri Sakamoto, Ami Sekine, Satomi Miyakawa, Tomohiro Umezu, et al. Potent antitumor effects of the conditioned medium of bone marrow-derived mesenchymal stem cells via IGFBP -4. Cancer Science. 2023

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MISC (144)：

桐林和代, 稲垣夏子, 梅津知宏, 黒田雅彦. Intracellular dynamics of Gb3 and ER stress in Fabry disease. 日本遺伝カウンセリング学会誌. 2023. 44. 2
工藤勇人, 梅津知宏, 齋藤彰, 松林純, 嶋田善久, 伊藤槙, 西平守道, 牧野洋二郎, 武内進, 前原幸夫, et al. 肺癌に対する血中遊離DNAからのmutational signatureの検出と低侵襲性早期診断システムの開発. 日本外科学会定期学術集会抄録集. 2022. 122回. SF-4
桐林和代, 藤田浩司, 梅津知宏, 稲垣夏子, 黒田雅彦. Distinction of urinary sediment in Fabry disease. 日本遺伝カウンセリング学会誌. 2022. 43. 2
桐林和代, 藤田浩司, 梅津知宏, 稲垣夏子, 黒田雅彦. ファブリー病患者の尿検体を用いた偏光顕微鏡下によるマルベリー小体検出の有用性について. 日本遺伝子診療学会大会プログラム・抄録集. 2022. 29th
桐林和代, 原田裕一郎, 梅津知宏, 稲垣夏子, 黒田雅彦. ファブリー病におけるマルベリー細胞の立体構造についての検討. 日本人類遺伝学会大会プログラム・抄録集. 2022. 67th (CD-ROM)

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Patents (2)：

Lectures and oral presentations (7)：

Identification of a novel stromal diffusible factor determining epithelial cell fate decision
(41st annual meeting for the japanese society of ddevelopmental biologists 2008)
Identification of a novel stromal diffusible factor determining epithelial cell fate decision
(41st annual meeting for the japanese society of ddevelopmental biologists 2008)
マウス胎仔卵管由来株細胞を用いた繊毛形成モデルの確立
(日本動物学会・2007年度年会 2007)
マウス卵管上皮の運命決定を担う間質由来因子の同定
(日本動物学会・2007年度年会 2007)
マウス卵管上皮種の決定メカニズムの解析
(日本分子生物学会・2007年度年会 2007)

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Education (4)：

- 2003 Tokyo University of Science Graduate School of Industrial Science and Technology
- 2003 Tokyo University of Science Graduate School, Division of Engineering Science
- 1999 Tokyo University of Science Faculty of Industrial Science and Technology Biological Science and Technology
- 1999 Tokyo University of Science Faculty of Engineering Science

Professional career (1)：

Doctor of Engineering (Tokyo University of Science)

Work history (2)：

2004 - 2006 Tokyo University of Science Faculty of Industrial Science and Technology
2004 - 2006 Research Associate, Biological Science and Technology, Tokyo University of Science

Awards (2)：

2005 - 日本動物学会平成17年度論文賞
2005 - Zoological Science Award

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