Rchr
J-GLOBAL ID:200901065275485481
Update date: Jul. 17, 2024
Ishino Yoshizumi
イシノ ヨシズミ | Ishino Yoshizumi
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://www.agr.kyushu-u.ac.jp/lab/seibutsukagaku/
Research field (4):
Applied biochemistry
, Structural biochemistry
, Functional biochemistry
, Molecular biology
Research keywords (6):
Archaea
, Protein chemistry
, DNA Repair
, DNA Replication
, Archaeal Biology
, DNA recombinational Repair
Research theme for competitive and other funds (24):
- 2020 - 2023 Functional analysis of novel Cas protein candidates for development of new genetic engineering technology
- 2019 - 2022 Elucidation of the life-sustaining mechanism of hyperthermophilic archaea without DNA replication origin
- 2018 - 2021 Cryo-EM analysis of the 3D-structure and mechanism of okazakisome
- 2014 - 2017 Structural study on the clamp PCNA-loading mechanism by the clamp loader RFC
- 2014 - 2017 Studies on genome integrity of archaea in the extremophilic environments
- 2013 - 2016 Attempts in unifying biological molecular data via graph methods
- 2012 - 2016 Structural analysis to investigate the coordinating role of DNA clamp in replisome
- 2011 - 2016 Digital DNA chipによる生物多様性評価と環境予測法の開発 研究課題
- 2012 - 2014 Development of novel labeling technique for macro molecule structure analysis
- 2011 - 2014 How is the genome integrity of the hyperthermophiles protected and propagated?
- 2009 - 2014 Target recognition and expression mechanism of intrinsically disordered protein
- 2009 - 2014 Regulatory functions of IDPs in the nuclear network of the genetic information systems
- 2009 - 2011 Molecular architecture and regulation mechanism of replication fork complex revealed by single partic le analysis
- 2008 - 2010 Principle of replication machinery for archaeal DNA replication
- 2005 - 2009 Studies on assembly, maintenance, and reorganization of replication fork complexes
- 2006 - 2007 DNA複製における不連続合成装置複合体形成と再編
- 2004 - 2007 Large scale collection and their industrial application of hyperthemophilic archaeal genome from deep sea hydrothermal envirenments
- 2005 - 2005 DNA複製装置レプリソーム超複合体の再編による機能変換
- 2003 - 2005 Structural and functional analyses of the DNA replication machinery called replisome complex
- 2002 - 2005 Structural and functional analyses of the initiation mechanism of archaeal DNA replication
- 2001 - 2005 Mechanisms of Formation and Resolution of Holliday junction in Recombination and Replication
- 2005 - DNA複製装置レプリソーム超複合体の再編による機能変換 研究課題
- 2001 - 2002 時計タンパク質複合体のX線結晶構造解析と複合体形成のダイナミクス
- 2000 - 2002 Isolation of novel thermophilic organisms from marine hydrothermal environments and the development of new catalytic functions
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Papers (215):
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Satoshi Nagai, Sirje Sildever, Noriko Nishi, Satoshi Tazawa, Leila Basti, Takanori Kobayashi, Yoshizumi Ishino. Comparing PCR-generated artifacts of different polymerases for improved accuracy of DNA metabarcoding,. Metabarcoding and Metagenomics. 2022. 6. 27-39
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Aya Fujikane, Atsuhiko Sakamoto, Ryosuke Fujikane, Akinori Nishi, Yoshizumi Ishino, Kenji Hiromatsu, Shigeki Nabeshima. Ephedrae Herba and Cinnamomi Cortex interactions with G glycoprotein inhibit respiratory syncytial virus infectivity. Communications biology. 2022. 5. 1. 94-94
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Shoji Suzuki, Norio Kurosawa, Takeshi Yamagami, Shunsuke Matsumoto, Tomoyuki Numata, Sonoko Ishino, Yoshizumi Ishino. Genetic and biochemical characterizations of aLhr1 helicase in the thermophilic crenarchaeon sulfolobus acidocaldarius. Catalysts. 2022. 12. 1
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Kazutoshi Yoshitake, Gaku Kimura, Tomoko Sakami, Tsuyoshi Watanabe, Yukiko Taniuchi, Shigeho Kakehi, Akira Kuwata, Haruyo Yamaguchi, Takafumi Kataoka, Masanobu Kawachi, et al. Development of a time-series shotgun metagenomics database for monitoring microbial communities at the Pacific coast of Japan. Scientific Reports. 2021. 11. 1
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Keisuke Oki, Mariko Nagata, Takeshi Yamagami, Tomoyuki Numata, Sonoko Ishino, Takuji Oyama, Yoshizumi Ishino. Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome. Nucleic acids research. 2021. 50. 7. 3601-3615
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MISC (209):
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小田隆, 大井里香, 古寺哲幸, 安藤敏夫, 小沼剛, 菅瀬謙治, 苙口友隆, 井上倫太郎, 杉山正明, 石野園子, et al. Integrated approach using small angle X-ray scattering and computational analysis for understanding dynamic structure and function of intrinsically disordered protein. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
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鈴木匠爾, 鈴木匠爾, 黒沢則夫, 山上健, 沼田倫征, 石野園子, 石野良純. 好熱性アーキアにおけるDNA修復に働く新規ヘリカーゼ様タンパク質の機能解析. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
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沖啓輔, 山上健, 永田麻梨子, 高島夏希, 真柳浩太, 白井剛, 石野園子, 石野良純. 超好熱性アーキアThermococcus kodakarensis由来ファミリーD DNAポリメラーゼの分子解剖による機能分布の解明. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st. ROMBUNNO.2P-0079 (WEB ONLY)
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真柳浩太, 沖啓輔, 石野園子, 宮崎直幸, 岩崎憲治, 神田大輔, 白井剛, 石野良純. クライオ電顕で「見る」古細菌複製フォーク複合体の機能構造. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st. ROMBUNNO.3AW-10-5 (WEB ONLY)
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真柳浩太, 沖啓輔, 石野園子, 宮崎直幸, 岩崎憲治, 神田大輔, 白井剛, 石野良純. PolD-PCNA-DNA複合体の単粒子解析. 日本生化学会大会(Web). 2017. 90th. ROMBUNNO.2P-0585 (WEB ONLY)-0585]
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Patents (81):
Books (6):
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アーキア生物学
共立出版 2017 ISBN:9784320057852
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ゲノム編集入門 : ZFN・TALEN・CRISPR-Cas9
裳華房 2016 ISBN:9784785358662
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DNA複製装置複合体(レプリソーム)の全体像を探る
[九州大学] 2006
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化学と生物実験ライン48、タンパク質と核酸の分離精製
広川書店 2001
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改定PCR Tips.
秀潤社 1999
more...
Education (4):
- 1983 - 1987 Osaka University Research Institute for Microbial Diseases
- 1981 - 1983 大阪大学大学院 薬学研究科 薬品化学専攻
- - 1983 Osaka University Graduate School, Division of Pharmaceutical Sciences Phanmacentical Chmistry
- 1977 - 1981 Osaka University School of Pharmaceutical Sciences
Professional career (1):
Work history (5):
- 2002/06 - 現在 Kyushu University Faculty of Agriculture
- 1996/04 - 2002/05 生物分子工学研究所
- 1983/04 - 1996/03 Takara Shuzo Co., Ltd.
- 1987/08 - 1989/08 Yale University Post Doctoral Fellow
- Principal Research Scientist, Biomolecular Engineering Research Institute
Awards (4):
- 2022/09 - 日本遺伝学会 日本遺伝学会木原賞
- 2019/06 - Genetics Promotion Foundation Genetics Promotion
- 2018/03 - 日本農芸化学会 農芸化学会賞
- 2017/12 - 第1回日本医療研究開発大賞 文部科学大臣賞
Association Membership(s) (7):
日本アーキア研究会
, 極限環境生物学会
, 日本蛋白質科学会
, 日本遺伝学会
, 日本生化学会
, 日本分子生物学会
, 日本農芸化学会
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