Rchr
J-GLOBAL ID:200901069922275287
Update date: Oct. 06, 2024
Takagi Atsuya
タカギ アツヤ | Takagi Atsuya
Affiliation and department:
Research field (2):
Environmental effects of chemicals
, Environmental effects of radiation
Research keywords (2):
毒性学
, toxicology
Research theme for competitive and other funds (13):
- 2007 - 2009 サリドマイドの奇形誘発機序の研究
- 2007 - 2009 Studies on molecular mechanisms of thalidomide-induced teratogenesis using human mesenchymal tem cells
- 1999 - 2001 Developmental genetics involved in the mechanism of vertebrate somitogenesis
- 2000 - 2000 体節形成過程にのみMesp1,Mesp2遺伝子を欠損したマウスの作成と解析
- 1996 - 1998 Construction of mouse embryonic stem cells for the detection of gene mutation
- 1996 - 1998 Signal transduction mediated by hematopoietic factors and TGF-β in p53-deficient mice
- 1997 - 1997 薬剤評価モデルとしてのヒト型造血因子受容体遺伝子導入マウスとその造血幹細胞動態制御
- 1996 - 1996 初代培養肝細胞におけるアポトーシス制御機構の解明
- 1996 - 1996 遺伝子改変動物の造血幹細胞動態制御を指標としたサイトカイン系薬剤評価モデルの開発
- ナノマテリアルの発がん性に関する研究
- ES細胞を用いた発生毒性研究
- ダイオキシンの毒性に関する研究
- toxicological science
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Papers (32):
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Toshime Igarashi, Yukuto Yasuhiko, Ryuichi Ono, Erika Tachihara, Miki Uchiyama, Atsuya Takagi, Yu Takahashi, Makiko Kuwagata, Satoshi Kitajima. Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system. Fundamental Toxicological Sciences. 2021. 8. 5. 161-167
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TAQUAHASHI Yuhji, TAKAGI Atsuya, OGAWA Yukio, TSUJI Masaki, MORITA Koichi, IMAIDA Katsumi, KANNO Jun. A comparison of lung burden between pristine and highly-dispersed, aggregate/agglomerate-eliminated MWCNT (Taquann method) in whole body inhalation exposure to mice. Annual Meeting of the Japanese Society of Toxicology. 2016. 43. O-38
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KANNO Jun, TAQUAHASHI Yuhji, TAKAGI Atsuya, OGAWA Yukio, HIROSE Akihiko, ISHIMARU Naozumi, IMAIDA Katsumi. Hazard assessment of nanomaterials with the use of taquann-injection whole body inhalation system. Annual Meeting of the Japanese Society of Toxicology. 2015. 42. S4-5
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Yuhji Taquahashi, Yukio Ogawa, Atsuya Takagi, Masaki Tsuji, Koichi Morita, Jun Kanno. An improved dispersion method of multi-wall carbon nanotube for inhalation toxicity studies of experimental animals. JOURNAL OF TOXICOLOGICAL SCIENCES. 2013. 38. 4. 619-628
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Fujimoto N, Takagi A, Kanno J. Neonatal exposure to 2,3,7,8-tetrachlorodibenze-p-dioxin increases the mRNA expression of prostatic proteins in C57BL mice. The Journal of toxicological sciences. 2013. 38. 2. 279-283
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MISC (20):
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Toshime Igarashi, Yukuto Yasuhiko, Ryuichi Ono, Erika Tachihara, Miki Uchiyama, Atsuya Takagi, Yu Takahashi, Makiko Kuwagata, Satoshi Kitajima. Germline-transmission in the knock-in mice of N0 generation with diverse and unintended on-target mutations induced by CRISPR/Cas9-mediated genome editing. 2021. 46. Supplement. P-91
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Y. Taquahashi, A. Takagi, K. Morita, M. Tsuji, K. Imaida, J. Kanno. Level of dispersion of MWCNT aerosol affects the lung burden and lung lesion in whole body inhalation study. TOXICOLOGY LETTERS. 2016. 259. S185-S185
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Ryo Ohta, Atsuya Takagi, Hideo Ohmukai, Hideki Marumo, Atsushi Ono, Yuko Matsushima, Tohru Inoue, Hiroshi Ono, Jun Kanno. Ovariectomized mouse uterotrophic assay of 36 chemicals. Journal of Toxicological Sciences. 2012. 37. 879-889
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相崎 健一, 五十嵐 勝秀, 種村 健太郎, 安彦 行人, 高橋 祐次, 高木 篤也, 北嶋 聡, 菅野 純. Percellomeプロジェクト・オンライン解析システム. The Journal of Toxicological Sciences. 2011. 36. Suppl. S214-S214
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J. Kanno, A. Takagi, T. Nishimura, A. Hirose. Nanomaterial toxicology-Importance of chronic toxicity assessment. TOXICOLOGY LETTERS. 2010. 196. S280-S280
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Books (2):
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ヒト型モデル動物
シュプリンガ-・フェアラ-ク東京 2002
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内分泌撹乱化学物質の生物試験研究法
シュプリンガ-・フェアラ-ク東京 2000
Lectures and oral presentations (3):
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p53+/-マウス腹空内投与による多層型カーボンナノチューブの中皮腫誘発作用について
(第35回日本トキシコロジー学会学術年会 2008)
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QUANTITATIVE MICROARRAY ANALYSIS BY "PERCELLOME" METHOD OF MURINE EMBRYONIC STEM CELLS AND EMBRYOID BODIES.
(Society of Toxicology 47th Annual Meeting 2008)
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QUANTITATIVE MICROARRAY ANALYSIS WITH “PERCELLOME” METHOD IN 2,3,7,8-TETRACHLORODIBENZO-p-DIOXIN-TREATED MURINE FETAL PALATE
(Society of Toxicology 46th Annual Meeting 2007)
Professional career (1):
- Doctor of Veterinary (日本獣医生命科学大学)
Committee career (2):
- - 現在 日本実験動物学会 評議員
- 日本毒性学会 評議員
Awards (1):
- 2011/07 - Pfizer Highly Cited Paper Award Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube
Association Membership(s) (4):
日本実験動物医学会
, THE JAPANESE SOCIETY OF VETERINARY SCIENCE
, 日本実験動物学会
, THE JAPANESE SOCIETY OF TOXICOLOGY
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