Omote Hiroshi

オモテヒロシ | Omote Hiroshi

Affiliation and department：

Research field (3)： Functional biochemistry , Neuroscience - general , Pharmaceuticals - health and biochemistry

Research keywords (11)：ポリアミン , VitaminC , drug export , chemical transmission , nucleotide transporter , polyamine transporter , glucose transporter , グルタミン酸輸送体 , ATP合成酵素 , P-糖タンパク質 , transporter

Research theme for competitive and other funds (15)：

2021 - 2024 ノルアドレナリン合成に関わる小胞型アスコルビン酸トランスポーターの同定
2017 - 2020 Identification of the vesicular ascorbic acid transport system
2013 - 2015 Novel Transport Assay System by SPA Method
2011 - 2012 Development of oriented reconstitution methods for membrane proteins
2009 - 2012 Molecular mechanism of the multi-transportmachinery

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Papers (83)：

Loc Dinh Hoang, Eriko Aoyama, Miki Hiasa, Hiroshi Omote, Satoshi Kubota, Takuo Kuboki, Masaharu Takigawa. Positive Regulation of S-Adenosylmethionine on Chondrocytic Differentiation via Stimulation of Polyamine Production and the Gene Expression of Chondrogenic Differentiation Factors. International Journal of Molecular Sciences. 2023. 24. 24. 17294-17294
Shunsuke Matsuo, Miki Hiasa, Hiroshi Omote. Functional characterization and tissue localization of the facilitative glucose transporter GLUT12. The Journal of Biochemistry. 2020. 168. 6. 611-620
Seiko Nakamura, Aiko Matsui, Shiori Akabane, Yasushi Tamura, Azumi Hatano, Yuriko Miyano, Hiroshi Omote, Mizuho Kajikawa, Katsumi Maenaka, Yoshinori Moriyama, et al. The mitochondrial inner membrane protein LETM1 modulates cristae organization through its LETM domain. Communications biology. 2020. 3. 1. 99-99
Iwai Y, Kamatani S, Moriyama S, Omote H. Function of essential chloride and arginine residue in nucleotide binding to vesicular nucleotide transporter. Journal of biochemistry. 2019. 165. 6. 479-486
Kawasaki T, Matsumoto T, Iwai Y, Kawakami M, Juge N, Omote H, Nabekura T, Moriyama Y. Purification and reconstitution of polyspecific H⁺/organic cation antiporter human MATE1. Biochimica et biophysica acta. Biomembranes. 2018. 1860. 11. 2456-2464

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MISC (39)：

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Patents (19)：

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Lectures and oral presentations (21)：

グルコーストランスポーター(GLUT8)は副腎クロマフィン細胞でのノルアドレナリン合成に関わっている
(日本生体エネルギー研究会第48回討論会 2022)
Vesicular polyamine transporter mediates vesicular storage and release of polyamine from MEG-01 cells
(2021)
Vesicular polyamine transporter mediates vesicular storage and release of polyamine from MEG-01 cells
(Japan Bioenergetics Group 2021)
グルコーストランスポーターGLUT12の輸送機能と組織化学的解析
(日本生体エネルギー研究会 2020)
Biochemical and mutational analysis of Plasmodium falciparum chloroquine resistance transporter (PfCRT)
(2020)

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Education (3)：

1990 - 1993 Osaka University Graduate School of Science
1988 - 1990 Shizuoka University Graduate School of Science
1983 - 1987 Shinshu University Faculty of Science

Professional career (1)：

Ph.D. (Osaka University)

Work history (7)：

2021/04 - 現在 Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Membrane Biochemistry & Biophysiology Associate professor
2007/04 - 現在 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
2005/04 - 2007/03 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
2004/04 - 2005/03 Okayama University The Graduate School of Natural Science and Technology
1999/04 - 2004/03 米国バージニア大学分子生理学生物物理学教室リサーチアソシエイト

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Awards (1)：

2014 - 文部科学省文部科学大臣賞「医学薬学的に重要なトランスポーターの発見と解析技術の研究」

Association Membership(s) (6)：

Japan Bioenergetics Group , Biophysical Society (USA) , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE BIOPHYSICAL SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY

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