Okabe Koji

2014 - 2017 Elucidation of pathological molecular mechanism of Notch2-Hajdu Cheney Syndrome type mutation

2013 - 2016 Elucidation of the functional roles of Ca2+-activated potassium channels in osteoclastic bone resorption

2013 - 2016 Elucidation of a mechanism of tooth mineralization through TRP channel

2012 - 2015 Elucidation of the influence of hyperlipidemia to give to a function of osteoclast caused by the periodontal disease

2012 - 2015 A novel regulation of farnesyl diphosphate synthase (FDPS) on the activity of Cl- extrusion in osteoclasts

2009 - 2011 Analysis of acid extrusion mechanism through new regulatory protein during bone resorption

2009 - 2011 Role of transient receptor potential(TRP) of Ca^<2+>-permeable cation channels in osteoclast apoptosis

2008 - 2010 Regulatory mechanisms of Ca^<2+> oscillations and transcription factor NFAT in osteoclastogenesis.

2007 - 2008 Functional relationships between Clcn7 and V-ATPase in osteoclastic acid secretion

2006 - 2008 Role of transient receptor potentials (TRPs) of Ca^<2+>-permeable cation channels in osteoclast differentiation

2006 - 2007 Molecular identification and functional analysis of Na^+/Ca^<2+> exchanger (NCX) associated with osteoclastic bone resorption

2005 - 2006 CLCN7 POINT MUTANT INHIBITED Cl-EXTRUSION, RESUTLING IN OSTEOPETROSIS

2004 - 2005 Regulatory mechanisms of ion transporters expressed in ruffled-border of osteoclasts

2004 - 2005 The role of phosphorylation of p65 subunit on transcriptional activity of NF-κB

2003 - 2005 MOLECULAR IDENTIFICATION AND FUNCTIONAL ANALYSIS OF Cl^- CHANNELS CONTRIBUTING OSTEOCLASTIC BONE RESORPTION.

2002 - 2003 Regulatory mechanisms of proton extrusion in osteoclasts via RANKL-TRAF signal.

2000 - 2001 The regulatory mechanisms of mechanical stress-induced ionic channels in osteocytes

1997 - 1998 プロテインキナーゼAによる破骨細胞カルシトニン感受性イオンチャネルの調節機構

1995 - 1995 破骨細胞イオンチャネルとカルシトニンの受容体情報伝達機構

1994 - 1994 破骨細胞イオンチャネルに対するカルシトニンの作用

1993 - 1993 単離子宮平滑筋細胞を用いた、エストロゲンのイオンチャネルに対する作用

1992 - 1993 Intracelluar signal transduction of relaxin : comparative study with beta-adrenergic action

1990 - 1991 Relaxin action on myometrial contractility

骨系細胞におけるメカニカルストレス受容の細胞内情報伝達の研究

破骨細胞の骨吸収機能調節に関する研究

子宮平滑筋の細胞生理学的研究

骨細胞におけるメカニカルストレス受容の細胞内情報伝達

破骨細胞の分子生理学的研究

Research on Signal-transduction of Mechanosensing in Bone Cells

Research on Regulation of Bone Resorption Activity in Osteoclasts

Cellular Physiology of Uterine Smooth Muscle

Signal-transduction of Mechanical Stress in Osteocytes

Molecular Physiology of the Osteoclast