Hatakeyama Tomomitsu

ハタケヤマトモミツ | Hatakeyama Tomomitsu

Affiliation and department：
Job title： Professor
Homepage URL (2)： http://www.cms.nagasaki-u.ac.jp/lab/seitai/index.html , http://www.ch.nagasaki-u.ac.jp/bio/

Research field (3)： Structural biochemistry , Applied biochemistry , Molecular biochemistry

Research keywords (8)： X-ray crystallographic analysis , marine animal , 海産動物 , X線結晶構造解析 , carbohydrate , toxin , lectin , protein

Research theme for competitive and other funds (21)：

2017 - 2020 Elucidation of novel functions of marine invertebrate lectins based on their structural diversity and its application
2014 - 2017 Elucidation of the action mechanisms lectins through protein engineering techniques and their application to the development of novel functions
2011 - 2014 カルシウム依存性レクチンの糖鎖認識機構及び細胞膜内イオンチャネル形成機構の解明
2008 - 2011 立体構造を基盤とした動物レクチン-糖鎖間相互作用の解明
2005 - 2007 レクチンの糖認識機構解析及びそのタンパク質工学的改変による有用タンパク質開発

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Papers (136)：

Tomomitsu Hatakeyama, Fuki Kojima, Issei Ohkawachi, Hitomi Sawai, Hideaki Unno. Carbohydrate-binding ability of a recombinant protein containing the DM9 motif from Drosophila melanogaster. The Journal of Biochemistry. 2024
Tomomitsu Hatakeyama, Kazuki Masuda, Mizuki Kudo, Koshi Tanaka, Ayaka Takeuchi, Hideaki Unno. Mannose oligosaccharide recognition of CGL1, a mannose-specific lectin containing DM9 motifs from Crassostrea gigas, revealed by X-ray crystallographic analysis. Journal of biochemistry. 2023. 175. 1. 35-41
Tomomitsu Hatakeyama, Hideaki Unno. Functional Diversity of Novel Lectins with Unique Structural Features in Marine Animals. Cells. 2023. 12. 14. 1814-1814
Masataka Kawakita, Taiki Oyama, Ikuma Shirai, Shuto Tanaka, Kotaro Akaki, Shinya Abe, Takuma Asahi, Guangwei Cui, Fumie Itoh, Masato Sasaki, et al. Cell wall N-glycan of Candida albicans ameliorates early hyper- and late hypo-immunoreactivity in sepsis. Communications Biology. 2021. 4. 1
Tomomitsu Hatakeyama, Akihiro Kishigawa, Hideaki Unno. Molecular cloning and characterization of the two putative toxins expressed in the venom of the devil stinger Inimicus japonicus. Toxicon. 2021. 201. 9-20

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MISC (46)：

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Books (10)：

Lectin Purification and Analysis
2020 ISBN:9781071604298
Lectin Purification and Analysis
2020 ISBN:9781071604298
Lectins Methods and Protocols
Humana Press inc. (Springer) 2014 ISBN:9781493912919
機能性糖質素材の開発と食品への応用II
(株)シーエムシー出版 2013 ISBN:9784781308234
はじめて学ぶ生命科学の基礎(畠山智充,小田達也編著)
株式会社化学同人 2011 ISBN:9784759814545

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Lectures and oral presentations (66)：

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Works (12)：

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Education (4)：

Professional career (1)：

Work history (8)：

2011/04 - 現在 Nagasaki University Graduate School of Engineering Professor
2005/07 - 2011/03 Nagasaki University Faculty of Engineering, Department of Applied Chemistry
1996/04 - 2005/06 Nagasaki University Faculty of Engineering, Department of Applied Chemistry
1996 - 2005 Associate Professor,Applied Chemistry,Faculty of Engineering,Nagasaki University
2005 - Professor,Applied Chemistry,Faculty of Engineering,Nagasaki University

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Committee career (4)：

Awards (2)：

1997 - 日本農芸化学会農芸化学奨励賞
1997 - The Japan Bioscience, Biotechnology, and Agrochemistry; Society Award for Encouragement of Young Scientists

Association Membership(s) (7)：

日本糖質学会 , アメリカ生化学分子生物学会 , 日本結晶学会 , 日本生物物理学会 , 日本蛋白質科学会 , 日本生化学会 , 日本農芸化学会

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