Hata Shoji

ハタショウジ | Hata Shoji

Affiliation and department：
Job title： Chief Researcher
Homepage URL (1)： http://www.igakuken.or.jp/calpain/

Research field (4)： Pharmaceuticals - health and biochemistry , Cell biology , Functional biochemistry , Pathobiochemistry

Research keywords (2)：カルパイン , 細胞内タンパク質分解

Research theme for competitive and other funds (17)：

2020 - 2023 カルパインの酵素活性異常を介した難治性皮膚炎発症の分子機構解明
2014 - 2018 Molecular mechanisms of gastric defense and intestinal immunity involving calpains
2011 - 2015 Developing sensor-proteins to detect CAPN3 protease activity
2011 - 2015 Tissue-specific functional studies on calpains
2014 - 2015 細胞内プロテアーゼ「G-カルパイン」による対アルコール胃粘膜防御の分子機構解析

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Papers (61)：

Koichi Ojima, Shoji Hata, Fumiko Shinkai-Ouchi, Yasuko Ono, Susumu Muroya. Calpain-3 not only proteolyzes calpain-1 and -2 but also is a substrate for calpain-1 and -2. Journal of biochemistry. 2023
Yasuko Ono, Fumiko Shinkai-Ouchi, Aya Noguchi, Shoji Hata. Enzymes | Calpains. Encyclopedia of Biological Chemistry III. 2021. 280-291
Fumiko Shinkai-Ouchi, Mayumi Shindo, Naoko Doi, Shoji Hata, Yasuko Ono. Calpain-2 participates in the process of calpain-1 inactivation. Bioscience reports. 2020
Koichi Ojima, Shoji Hata, Fumiko Shinkai-Ouchi, Mika Oe, Susumu Muroya, Hiroyuki Sorimachi, Yasuko Ono. Developing fluorescence sensor probe to capture activated muscle-specific calpain-3 (CAPN3) in living muscle cells. Biology open. 2020. 9. 9
Shoji Hata, Naoko Doi, Fumiko Shinkai-Ouchi, Yasuko Ono. A muscle-specific calpain, CAPN3, forms a homotrimer. Biochimica et biophysica acta. Proteins and proteomics. 2020. 1868. 7. 140411-140411

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MISC (4)：

尾嶋孝一, 秦勝志, 大内史子, 小野弥子, 室谷進, 室谷進. カルパイン3はカルパインカスケードの上流に位置する. 日本食肉科学会大会講演要旨. 2024. 65th
尾嶋孝一, 秦勝志, 大内史子, 小野弥子, 室谷進. 骨格筋特異的に発現するカルパイン3は組織普遍的なカルパイン1および2を基質とする. 日本畜産学会大会講演要旨. 2023. 131st
尾嶋孝一, 秦勝志, 大内史子, 大江美香, 室谷進, 反町洋之, 小野弥子. タンパク質分解酵素であるカルパイン3の活性を検出するプローブ. 農研機構畜産研究部門成果情報(Web). 2020. 2020
中島健一朗, 朝倉富子, 松本一朗, 秦勝志, 反町洋之, 阿部啓子. 新規味覚修飾タンパク質“ネオクリン”の遺伝子構造の解析. 日本農芸化学会大会講演要旨集. 2005. 2005

Patents (2)：

Books (6)：

Impact
Science Impact Ltd. 2018
Encyclopedia of Biological Chemistry, 2nd Edition
Elsevier Academic Press 2013
Handbook of Proteolytic enzymes, 3rd Edition
Elsevier Academic Press 2012
生物機能モデルと新しいリソース・リサーチツール
2010
Calcium and Muscle disease: Pathophysiology of Calpains and Limb Girdle Musclular Dystrophy Type 2A (LGMD2A)
Calcium:The Molecular Basis of Calcium Action in Biology and Medicine 2000

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Education (4)：

1998 - 2001 The University of Tokyo Graduate School of Agricultural and Life Sciences
1996 - 1998 The University of Tokyo Graduate School of Agricultural and Life Sciences
1994 - 1996 The University of Tokyo
1992 - 1994 The University of Tokyo

Professional career (2)：

Work history (5)：

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