Rchr
J-GLOBAL ID：200901077841419309   Update date: Jun. 01, 2024

Makishima Hideki

マキシマ ヒデキ | Makishima Hideki
Affiliation and department：
Shinshu University School of Medicine, Department of Hematology and Medical Oncology

About Shinshu University School of Medicine, Department of Hematology and Medical Oncology


Research field  (3)： Hematology and oncology ,  Tumor biology ,  Hematology and oncology
Research keywords  (7)： 骨髄異形成骨髄増殖性疾患 ,  骨髄増殖性疾患 ,  急性骨髄性白血病 ,  がんゲノム ,  発作性夜間血色素尿症 ,  Aplastic anemia ,  Myelodysplastic syndromes
Research theme for competitive and other funds  (6)：
  • 2019 - 2024 comprehensive studies on the molecular basis of early development and clonal evolution in cancer using advanced genomics.
  • 2019 - 2024 Clinical application of germline and somatic mutations in bone marrow failure syndromes.
  • 2015 - 2020 Research on cancer evolution and heterogeneity using large-scale sequencing
  • 2016 - 2019 Molecular pathogenesis of bone marrow failure elucidated by comprehensive sequencing.
  • 2015 - 2016 骨髄系腫瘍における網羅的エクソーム・ゲノム解析
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Papers (225)：
  • 中川 正宏, 稲垣 良作, 黒田 隆, 南谷 泰仁, 趙 蘭英, 越智 陽太郎, 本村 公則, 竹田 淳恵, 戚 星星, 岡崎 幸治, et al. 単一細胞マルチオミクス解析によるクローン造血の病態解明. 日本血液学会学術集会. 2023. 85回. 287-287
  • 奥田 瑠璃花, 越智 陽太郎, 佐伯 龍之介, 真田 昌, 半田 寛, 白石 友一, 千葉 滋, 石川 隆之, 大屋敷 一馬, 熱田 由子, et al. der(1;7)(q10;p10)を有するMDSと関連疾患のクローン構成(Clonal structure of myeloid neoplasms with der(1;7)(q10;p10)). 日本癌学会総会記事. 2023. 82回. 538-538
  • 依田 成玄, 森下 大輔, 越智 陽太郎, 水谷 明生, 森 拓人, 竹田 淳恵, 戸崎 浩和, 佐藤 義彦, 牧島 秀樹, 中川 正宏, et al. がんのRNA異常の核心に迫る/The Nexus of RNA Dysregulation in Cancer 骨髄性腫瘍を標的とした新規スプライシング阻害剤CTX-712の開発(CTX-712, a novel splicing inhibitor targeting myeloid neoplasms). 日本癌学会総会記事. 2023. 82回. 737-737
  • 戚 星星, Yoshizato Tetsuichi, 南谷 泰仁, Nakagawa Masahiro M., 昆 彩奈, 森 拓人, 依田 成玄, 越智 陽太郎, 竹田 淳恵, 佐伯 龍之介, et al. 骨髄系腫瘍におけるU2AF2体細胞突然変異によるミスプライシング(Mis-splicing due to somatic U2AF2 mutations in myeloid neoplasms). 日本癌学会総会記事. 2023. 82回. 1684-1684
  • 昆 彩奈, 中川 正宏, 片岡 圭亮, 森 拓人, 垣内 伸之, 牧島 秀樹, 越智 陽太郎, 中山 学, 古関 明彦, 南谷 泰仁, et al. 骨髄系腫瘍におけるDDX41胚細胞変異・体細胞変異の分子病態の解明(Pathogenetic role of germline and somatic DDX41 mutations in the pathogenesis of myeloid malignancies). 日本癌学会総会記事. 2023. 82回. 1686-1686
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MISC (206)：
  • June Takeda, Kenichi Yoshida, Masahiro M. Nakagawa, Yasuhito Nannya, Akinori Yoda, Ryunosuke Saiki, Yotaro Ochi, Lanying Zhao, Rurika Okuda, Xingxing Qi, et al. Amplified EPOR/JAK2 genes definea unique subtype of acute erythroid leukemia. CANCER RESEARCH. 2022. 82. 12
  • June Takeda, Kenichi Yoshida, Masahiro Marshall Nakagawa, Yasuhito Nannya, Akinori Yoda, Daisuke Morishita, Ryunosuke Saiki, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, et al. EPOR/JAK/STAT Signaling Pathway As Therapeutic Target of Acute Erythroid Leukemia. BLOOD. 2021. 138
  • Ayana Kon, Masahiro Nakagawa, Ryosaku Inagaki, Keisuke Kataoka, Yotaro Ochi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa. The functional role of compound DDX41 germline and somatic R525H mutations in the development of myeloid neoplasms. CANCER SCIENCE. 2021. 112. 454-454
  • Masahiro Nakagawa, Ryosaku Inagaki, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, et al. Early Clonal evolution of myeloid malignancies. CANCER SCIENCE. 2021. 112. 969-969
  • Yotaro Ochi, Kenichi Yoshida, Ko Sasaki, Noriko Hosoya, Yusuke Shiozawa, Yasuhito Nannya, Takayuki Ishikawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, et al. Genetic profiling and prognosis of blast crisis in chronic myeloid leukemia. CANCER SCIENCE. 2021. 112. 454-454
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Patents (1)：
Professional career (1)：
  • 医学博士
Work history (10)：
  • 2024/01 - 現在 Shinshu University School of Medicine, Department of Hematology and Medical Oncology
  • 2018/04 - 2024/05 Kyoto University Graduate School of Medicine
  • 2018/03 - 現在 Kyoto University Pathology and Tumor Biology Associate Professor
  • 2015/03 - Kyoto University Graduate School of Medicine
  • 2008/04 - クリーブランドクリニック トーシックがんセンター ポストドクトラルフェロー
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Association Membership(s) (8)：
European society of hematology ,  American Society of Hematology ,  American College of Physicians ,  日本造血細胞移植学会 ,  日本臨床腫瘍学会 ,  THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE SOCIETY OF HEMATOLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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