Rchr

J-GLOBAL ID：200901078509684461 Update date: Sep. 30, 2024

Yashiro Masakazu

ヤシロマサカズ | Yashiro Masakazu

Affiliation and department：

Research field (2)： Digestive surgery , General surgery, pediatric surgery

Research keywords (2)： Oncology」 , Gastroenterol Surgery

Research theme for competitive and other funds (39)：

2024 - 2029 Development of companion tools for CXCL1 signaling target therapy against CAF in scirrhous gastric carcinoma
2024 - 2027 スキルス胃癌微小環境におけるCAF教育-進展機構の解明
2023 - 2026 Elucidation of Prostaglandin D Receptor-mediated Carcinogenesis Mechanism of Colitic Cancer
2023 - 2026 癌関連線維芽細胞の産生するCD9陽性エクソソームに含まれる悪性黒色腫抑制因子の同定
2024 - 2025 深海性放線菌が生産する天然物に着目したスキルス胃癌を特異的に排除する抗癌剤の開発

2022 - 2025 深海放線菌が産生する新規の胃癌抑制物質の同定

2022 - 2025 難治口腔がんに対するウイルス療法の開発-免疫チェックポイント阻害剤併用療法ー

2022 - 2025 深海放線菌が産生する新規の胃癌抑制物質の同定

2021 - 2025 Development of anti-scirrhous stomach cancer produced by the deep-sea actinomyces

2021 - 2024 Development of CXCL1 target therapy for cancer-associated fibroblasts in scirrhous gastric carcinoma

2021 - 2024 悪性黒色腫の原発巣から産生される転移巣抑制因子の解析と新たな治療法の開発

2021 - 2024 Development of CXCL1 target therapy for cancer-associated fibroblasts in scirrhous gastric carcinoma

2019 - 2023 Development of an automated exosome sensing array system for identification of refractory cancer biomarkers

2019 - 2023 Influence of Exosomes of Cancer-Associated Fibroblasts on Proliferation and Progression of Malignant Melanoma and Development of Inhibitors

2019 - 2023 Brandnew oncolytic virus therapy for oral cancer

2019 - 2023 難治口腔癌に対するウイルス療法の開発ー免疫チェックポイント阻害剤との併用療法ー

2019 - 2023 癌関連線維芽細胞のエクソソームが悪性黒色腫の増殖進展におよぼす影響と阻害剤の開発

2019 - 2023 難治癌バイオマーカー同定のためのエクソソーム自動センシングアレイシステムの開発

2018 - 2022 Mechanisms for the stromal construction of the scirrhous gastric cancer: role of myeloid cells and cancer stem cells on the formation of tumor stroma

2017 - 2019 Study of novel CAF led-type cancer invasion triggered by cancer death vesicles

2016 - 2019 The relationship between vancer-associated fibroblasts and malignant melanoma cells.

2014 - 2018 CONQUEST OF THE SCIRRHOUS GASTRIC CANCER: AUTOPHAGY OF CANCER STEM CELLS AND DEVELOPMENT OF MOLECULAR TARGET

2011 - 2015 Analysis of factors associated with the development of gastric cancer in hypoxic microenvironment

2010 - 2014 Molecular mechanisms responsible for the development of scirrhous gastric cancer: analysis of cancer stem cells.

2008 - 2010 Combination effects of kinase inhibitors with anti-cancer drugs on scirrhous gastric carcinoma.

2007 - 2009 Molecular targeting therapy of VEGF and PDGF receptor for colon cancer

2007 - 2009 Novel molecular target therapy for pancreatic cancer

2006 - 2009 Molecular targeting for scirrhous gastric cancer

2006 - 2008 The inhibitory effect on progression of scirrhous gastric carcinoma by blocking TGF-beta signal pathway

2006 - 2007 Effect of molecular targeting Compounds as KGFR or TGFβR Phosphorylation Inhibitors on the development of Gastric Cancer

2001 - 2004 Analysis of factors associated with peritoneal metastasis in gastric carcinoma

2001 - 2004 Mechanisms responsible for peritoneal metastasis and lymph node metastasis in scirrhous gastric carcinoma

1999 - 2000 胃癌腹膜播種性転移過程に関与する因子の検討

難治性癌の分子標的治療法の確立

消化器癌の遺伝子変化

胃癌の増殖進展および腹膜播種性転移に関する研究

Genetic alterations in gastrointestinal cancer

Study of tumor progression and peritoneal metastasis of gastric cancer

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Papers (499)：

Yuichiro Miki, Mami Yoshii, Ryoko Miyauchi, Hiroaki Kasashima, Tatsunari Fukuoka, Tatsuro Tamura, Masatsune Shibutani, Takahiro Toyokawa, Shigeru Lee, Masakazu Yashiro, et al. Prognostic significance of connective tissue growth factor expression in stromal cells in patients with diffuse-type gastric cancer. Oncology letters. 2024. 27. 6. 241-241
Tasuku Matsuoka, Masakazu Yashiro. Bioinformatics Analysis and Validation of Potential Markers Associated with Prediction and Prognosis of Gastric Cancer. International journal of molecular sciences. 2024. 25. 11
Hiroto Kinoshita, Anxo Martinez-Ordoñez, Tania Cid-Diaz, Qixiu Han, Angeles Duran, Yu Muta, Xiao Zhang, Juan F Linares, Yuki Nakanishi, Hiroaki Kasashima, et al. Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation. Developmental cell. 2024
Yoshinori Kikuchi, Hideaki Shimada, Fumiyuki Yamasaki, Taku Yamashita, Koji Araki, Kohei Horimoto, Satoshi Yajima, Masakazu Yashiro, Keigo Yokoi, Haruhiko Cho, et al. Clinical practice guidelines for molecular tumor marker, 2nd edition review part 2. International journal of clinical oncology. 2024. 29. 5. 512-534
Masaru Enomoto, Naoshi Odagiri, Koji Rinka, Hirotsugu Maruyama, Yoshinori Shimamoto, Yuki Ishikawa-Kakiya, Yasuhiro Fujiwara, Norifumi Kawada, Masakazu Yashiro. C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior. Journal of gastroenterology. 2024. 59. 2. 157-158

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MISC (990)：

田中正光, 堀江美里, 高金くらら, 伊藤剛, 栗山正, 柳原五吉, 八代正和. Exosomes of ST3G5^high cancer cells promote pre-metastatic niche of peritoneal dissemination. 日本癌学会学術総会抄録集(Web). 2023. 82nd
西村貞徳, 杉本敦史, 櫛山周平, 栂野真吾, 黒田顕慈, 山内真, 角俊幸, 金田裕靖, 川口知哉, 加藤実, et al. がん遺伝子パネル検査を用いたクリニカルシーケンスの課題と現状. 日本分子腫瘍マーカー研究会誌. 2021. 36. 5-6
豊川貴弘, 田村達郎, 櫻井克宣, 天野良亮, 久保尚士, 田中浩明, 六車一哉, 八代正和, 平川弘聖, 大平雅一. 切除可能胸部食道癌における治療前予後因子としての炎症・栄養マーカーの比較検討. 外科と代謝・栄養. 2018. 52. 3. 116-116
櫻井克宣, 久保尚士, 玉森豊, 西居孝文, 日月亜紀子, 井上透, 田村達郎, 豊川貴弘, 田中浩明, 六車一哉, et al. 高齢早期胃癌患者における予後影響因子とスコア化. 外科と代謝・栄養. 2018. 52. 3. 133-133
田村達郎, 櫻井克宣, 豊川貴弘, 久保尚士, 福岡達成, 大平豪, 渋谷雅常, 山添定明, 永原央, 木村健二郎, et al. 食道癌術前化学療法の治療効果予測におけるNLRの有用性. 外科と代謝・栄養. 2018. 52. 3. 143-143

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Patents (13)：

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Education (4)：

- 1995 Osaka City University
- 1995 Osaka City University Graduate School, Division of Medicine
- 1988 Osaka City University Medical School med
- 1988 Osaka City University Faculty of Medicine

Professional career (1)：

Doctor of Medicine

Awards (8)：

2007 - 日本消化器癌発生学会奨励賞
2006 - 癌研究奨励賞
2005 - 平成18年度大阪市医学会市長賞
1998 - 大阪市医学会市長賞
1997 - 大阪市医学会市長賞

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Association Membership(s) (10)：

日本消化器病学会 , 日本大腸肛門病学会 , 日本消化器内視鏡学会 , 日本乳癌学会 , 米国癌学会 , 日本消化器癌発生学会 , 日本胃癌学会 , 日本外科学会 , 日本消化器外科学会 , 日本癌学会

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