Rchr
J-GLOBAL ID：200901078527681011   Update date: May. 22, 2024

Masutani Mitsuko

マスタニ ミツコ | Masutani Mitsuko
Affiliation and department：
Nagasaki University Graduate School of Biomedical Sciences

About Nagasaki University Graduate School of Biomedical Sciences


Job title： Chief
Other affiliations (1)：
  • National Cancer Center Research Institute  Specially Appointed Chief
Research field  (6)： Pathobiochemistry ,  Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Cell biology ,  Molecular biology ,  Biochemistry
Research keywords  (16)： molecular medicine ,  drug development ,  radiation biology ,  BNCT (boron neutron capture therapy) ,  がん治療 ,  がん予防 ,  生化学 ,  発がん ,  DNA損傷応答 ,  翻訳後修飾 ,  ポリ(ADP-リボース) ,  Carcinogenesis ,  Biochemistry ,  DNA damage response ,  ADP-ribose ,  Poly(ADP-ribose)
Research theme for competitive and other funds  (25)：
  • 2018 - 2022 BNCTにおける治療局所・全身性応答と治療奏効性、副作用のバイオマーカーの同定
  • 2016 - 2019 Development of DNA damaging agents using poly(ADP-ribose) hydrolysates
  • 2015 - 2018 Study on characteristics of small RNA secreted from the pluripotent stem cells
  • 2015 - 2018 A comprehensive genome-wide screen of radiosensitization targets
  • 2014 - 2017 genome stability in germ-line stem cells to irradiation and exposure to chemicals
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Papers (116)：
  • Satoshi Nakamura, Mihiro Takemori, Tetsu Nakaichi, Yasunori Shuto, Tairo Kashihara, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Yuka Urago, Shuka Nishina, et al. A method for delivering the required neutron fluence in an accelerator-based boron neutron capture therapy system employing a lithium target. Scientific reports. 2024. 14. 1. 11253-11253
  • Yuka Sasaki, Takuma Inouchi, Ryusuke Nakatsuka, Amane Inoue, Mitsuko Masutani, Tadashige Nozaki. Activated NAD+ biosynthesis pathway induces olaparib resistance in BRCA1 knockout pancreatic cancer cells. PLOS ONE. 2024
  • Yuka Sasaki, Ryusuke Nakatsuka, Amane Inoue, Takuma Inouchi, Mitsuko Masutani, Tadashige Nozaki. Dysfunction of poly (ADP-ribose) glycohydrolase suppresses osteoclast differentiation in RANKL-stimulated RAW264 cells. Biochemical and biophysical research communications. 2023. 692. 149309-149309
  • Tong Ying, Gao Zhongming, Imamichi Shoji, Sanada Yu, 佐々木 由香, 野崎 中成, Suzuki Minoru, Masunaga Shinichiro, 益谷 美都子. BNCT後の早期反応バイオマーカーとしてのHMGB1の動的プロファイル(Dynamic profile of HMGB1 as a biomarker for the early response after BNCT). 日本癌学会総会記事. 2023. 82回. 2156-2156
  • Shoji Imamichi, Lichao Chen, Tasuku Ito, Ying Tong, Takae Onodera, Yuka Sasaki, Satoshi Nakamura, PierLuigi Mauri, Yu Sanada, Hiroshi Igaki, et al. Correction: Imamichi et al. Extracellular Release of HMGB1 as an Early Potential Biomarker for the Therapeutic Response in a Xenograft Model of Boron Neutron Capture Therapy. Biology 2022, 11, 420. Biology. 2023. 12. 8
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MISC (428)：
  • 益谷 美都子, 木村 雄亮, 池内 真志. 新型コロナウィルス感染早期診断用ポータブルデバイスの実用化検証. 生体医歯工学共同研究拠点成果報告書. 2023. 2022年度. 110-110
  • 村山広樹, TONG Ying, SARASWAT Barkha, 林康平, 林康平, 林康平, 益谷美都子. Development of evaluation model of flow cytometry for combination effects of anti-cancer agents using machine learning. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • VELU Ankitha Vadi, SARASWAT Barkha, TONG Ying, MYAT Aung Bhone, MATSUNO Kenji, TAKAMURA Takeji, KOIZUMI Fumiaki, MASUTANI Mitsuko. Cell death responses induced by a potential anti-cancer agent MO2455 in lymphoma U937 cells. 日本薬学会年会要旨集(Web). 2023. 143rd
  • MYAT Aung, NISHIYAMA Itsuki, TONG Ying, MASUTANI Mitsuko. Unravelling the combined therapeutic effect of PARP and microtubule inhibitors on on chromosomal hyperploidy induction and cell cycle arrest. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • TONG Ying, CHEN Lichao, CHEN Lichao, GAO Zhongming, IMAMICHI Shoji, IMAMICHI Shoji, IMAMICHI Shoji, SANADA Yu, SASAKI Yuka, NOZAKAI Tadashige, et al. The role of GM-CSF in the early response to BNCT. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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Patents (7)：
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Books (10)：
  • PARP inhibitors for Cancer Therapy.
    Springer International 2015
  • Polymerization
    In Tech 2012
  • DNA repair and human cancers : Extended abstracts for the 40th International Symposium of the Princess Takamatsu Cancer Research Fund : November 10-12, 2009 Tokyo, Japan
    Princess Takamatsu Cancer Research Fund 2010
  • New Developments in Stem Cell Research
    Nova Science Publishers, Inc. 2006
  • Poly(ADP-Ribosyl)ation
    Eurekah.com. 2004
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Education (6)：
  • Okayama University Faculty of Pharmaceutical Sciences Department of Pharmacy
  • Okayama University
  • The University of Tokyo
  • Okayama University Faculty of Pharmaceutical Science
  • Okayama University Graduate School, Division of Pharmaceutical Sciences
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Professional career (1)：
  • Ph.D. (The University of Tokyo)
Work history (11)：
  • 2019/10 - 現在 Nagasaki University Department of Molecular and Genomic Biomedicine, Center for Bioinformatics and Molecular Medicine, Graduate School of Biomedical Sciences Professor
  • 2015/02 - 2019/09 Nagasaki University Department of Frontier Life Sciences, Graduate School of Biomedical Sciences Professor
  • 2014/07 - 2015/01 National Cancer Center Division of Chemotherapy and Clinical Cancer Research
  • 2010 - 2014 National Cancer Center Division of Genome Stability Research
  • 2007/07 - 2010/11 National Cancer Center Research Institute Biochemistry Division Chief
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Awards (1)：
  • 2000 - 田宮賞
Association Membership(s) (9)：
Japanese Society of Neutron Capture Therapy(JSNCT) ,  The Japanese Society for Regenerative Medicine ,  Japanese Association for Molecular Target Therapy of Cancer ,  分子病理学研究会 ,  The Pharmaceutical Society of Japan ,  American Association for Cancer Research ,  日本分子生物学会 ,  日本生化学会 ,  日本癌学会
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