Rchr

J-GLOBAL ID：200901081664924097 Update date: Nov. 20, 2024

Takewa Yoshiaki

タケワヨシアキ | Takewa Yoshiaki

Affiliation and department：
Job title： Laboratory Chief

Research field (2)： Respiratory surgery , Cardiovascular surgery

Research keywords (12)：遺伝子治療 , 再生医療 , 補助循環 , 人工肺 , 人工心臓 , 心臓血管外科 , Gene therapy , Regeneration therapy , Assist circulation , Artificial lung , Artificial heart , Cardiovascular Surgery

Research theme for competitive and other funds (41)：

2024 - 2026 Research on the development of growing autologous tissue-derived transcatheter heart valves
2022 - 2026 Development of autologous transcatheter heart valves with growth potential
2019 - 2022 Development of growing cardiovascular grafts using bioabsorbable materials
2015 - 2019 Development of next-generation type autologous heart valve (biovalve)
2014 - 2017 The feasibility study of a novel autologous heart valve (biovalve stent)

2013 - 2017 Development of a catheter-based itravascular rotary blood pump for assisting selective blood circulation in heart failure

2013 - 2016 Development of a monitoring system for ventricular assist devices using an active sensing method

2013 - 2016 Development of a flow path regulating device for an implantable continuous flow artificial heart in cases of an irregular stop and a weaning test

2012 - 2015 Development of a Blood Pump for Implantable Right Ventricular Assist Device

2012 - 2015 Evaluation of the effect of electromagnetic exposure by implantable medical device

2012 - 2015 Development of an autonomous and flexible artificial heart control method to intervene in control of the cardiovascular system

2011 - 2015 Alternative approach for right ventricular failure after left ventricular assist device placement in animal model.

2011 - 2014 Development of a novel infection-resistant skin-button and cover materials for long-term VAD support

2011 - 2014 Development of completely autologous aortic valves by a novel concept of regenerative medicine

2011 - 2014 Development of a wearable pneumatic artificial heart system

2009 - 2014 Comprehensive study on research and development of circulatory assist systems for bettering therapeutic outcome of severe heart failure pediatric patients

2011 - 2013 Evaluation of a noble in-body tissue engineered heart valve (Biovalve) in the systemic circulation

2010 - 2012 Development of a implantable medical device with the self-curable NC-hydrogel.

2009 - 2012 Development of hybrid therapy of myocardial regenerative medicine and ventricular assist circulation to improve prognosis of heart transplant candidate

2008 - 2010 Development of a wearable pneumatic total artificial heart system aimed at permanent use

2007 - 2009 Research of the clinical issues relating to ventricular assist device treatment for severe heart failure

2006 - 2008 Development of the next-generation PCPS system for emergency and/or prolonged use without systemic anticoagulation therapy aiming at its practical use

2005 - 2007 Development of the next generation implantable pneumatic ventricular assist device for permanent use.

2005 - 2006 人工酸素運搬体と経皮的心肺補助(PCPS)を併用した新しい心肺蘇生法の開発

2005 - 2006 埋め込み型医用機器使用時の感染防御に有用な新規皮膚貫通部被覆デバイスの開発

2004 - 2006 心筋内移植細胞に対して機械的補助循環が与える力学的特性に関する研究

2005 - 2005 補助人工心臓によるブリッジからリカバリーを促進する心筋再生療法に関する研究

2003 - 2005 感温性ゼラチンを細胞外マトリックスに用いた生体内での三次元的心筋組織構築の試み

2003 - 2005 Miniaturization and Performance Enhancement of the Magnetically Levitated Centrifugal Pump as an Implantable Ventricular Assist Device

2002 - 2005 A comprehensive study on novel heart failure treatment strategy by means of next-generation circulatory assist devices in combination with gene therapy

2003 - 2004 体内埋め込み型および皮膚貫通型医療機器の局所感染防御のための新規被覆材の開発

2002 - 2004 Development of Combination Therapy Between Myocardial Regeneration and Ventricular Assist Device Support

2002 - 2004 Development of a totally implantable ventricular assist device system with improved antithrombogenicity and portability

2002 - 2003 定常流補助人工心臓のモータ電流を生体情報センサとして応用した自己心機能評価法

2001 - 2003 Development of a cardiopulmonary support system with excellent antithrombogenicity and durability that enables continuous long-term perfusion with minimum anticoagulant therapy

2001 - 2002 The pathological influence on ultrastructure of the red blood cell and the vascular system under long term circulation with continuous flow left heart bypass.

1998 - 2001 Research and development of an electrohydraulic totally implantable artificial heart system for practical use

1998 - 2000 Influences of Mid-to-Long Term Nonpulsatile Circulation on Function and Structure of the Living Body

1998 - 2000 Improvement of Biocompatibility of Mechanical Pump Systems for Artificial Hearts

人工臓器

Artificial organs

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Papers (129)：

永吉智紀, 井上雄介, 寺澤武, 佐藤康史, 武輪能明. カテーテル治療へ応用可能な自己組織生体弁(バイオバルブ)の開発. 北海道外科雑誌. 2024. 69. 1. 72-73
Hironobu Sakurai, Tatsuki Fujiwara, Katsuhiro Ohuchi, Wataru Hijikata, Yusuke Inoue, Osamu Maruyama, Tomoki Tahara, Sachie Yokota, Yui Tanaka, Yoshiaki Takewa, et al. Innovative experimental animal models for real-time comparison of antithrombogenicity between two oxygenators using dual extracorporeal circulation circuits and indocyanine green fluorescence imaging. Artificial organs. 2023. 47. 1. 77-87
山名智尋, 寺澤武, 堀江風花, 佐藤康史, 井上雄介, 武輪能明. 自己組織心臓弁グラフト形成用鋳型の開発と臨床応用の可能性検証. 北海道外科雑誌. 2022. 67. 1. 90-91
佐藤康史, 寺澤武, 井上雄介, 武輪能明. 生体内組織形成術を用いたBio-Culture-Plateの開発と性能評価. 北海道外科雑誌. 2022. 67. 1. 91-91
堀江風花, 井上雄介, 佐藤康史, 山名智尋, 寺澤武, 武輪能明. COVID-19肺炎重症例に対するECMO下での経気道的治療法確立への挑戦. 北海道外科雑誌. 2022. 67. 1. 91-91

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MISC (403)：

Inoue Y, Sato Y, Terazawa T, Yamada A, Takewa Y. Development of an aggressive therapy to administer drugs directly into the trachea to improve survival and achieve early weaning of patients on ECMO. ESAO Abstract Book. 2023. 46. 7. 434-434
井上雄介, 佐藤康史, 寺澤武, 武輪能明. ウイルス感染症などに起因する重症肺炎に対するECMO装着下での経気道的治療法の開発. 人工臓器(日本人工臓器学会). 2023. 52. 2
佐藤康史, 寺澤武, 井上雄介, 武輪能明. Development of Novel Autologous Tissue Engineered Artificial Heart Valves by in vivo Tissue Engineering Process. 日本生物工学会大会講演要旨集. 2023. 75th
武輪能明, 井上雄介, 寺澤武, 佐藤康史. 様々な大動脈弁疾患に対する自己組織生体弁を代用とする可能性の検討. 日本心臓血管外科学会学術総会(Web). 2023. 53rd
寺澤武, 寺澤武, 寺澤武, 佐藤康史, 井上雄介, 中西修一, 辻雅之, 山崎洸生, 白木秀幸, 武輪能明. 圧電性ポリ乳酸材料の荷電性が生体内形成組織の物性に与える影響. 人工臓器(日本人工臓器学会). 2023. 52. 2

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Patents (8)：

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Education (1)：

- 1990 Nara Medical University Medical Faculty

Professional career (1)：

医学博士 (奈良県立医科大学)

Awards (10)：

2017/06 - ASAIO Top Graded Abstracts
2014/09 - ESAO Poster Award
2014/02 - The Japanese Society for Cardiovascular Surgery Award of excellence
2014/02 - The Japanese Society for Cardiovascular Surgery Hearse & Yamamoto Award
2010/10 - International Society For Rotary Blood Pumps (ISRBP) Poster Award

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