Rchr
J-GLOBAL ID:200901085983212151
Update date: Sep. 03, 2024
Morimatsu Masami
モリマツ マサミ | Morimatsu Masami
Affiliation and department:
Job title:
Laboratory of Animal Experiment for Disease Model
Research field (3):
Experimental pathology
, Veterinary medicine
, Laboratory animal science
Research keywords (6):
獣医生化学
, 分子遺伝学
, 実験動物学
, Veterinary Biochemistry
, Molecular Genetics
, Laboratory Animal Science
Research theme for competitive and other funds (33):
- 2022 - 2025 NFkB情報伝達系が癌発症に及ぼす影響におけるNFKBIZの機能解明
- 2020 - 2023 感受性責任遺伝子探索による多包虫症の寄生体・宿主相互作用の分子機序の解明
- 2018 - 2021 腫瘍におけるBRCA2の変異と結合分子群の機能解明を目的とした新規モデルの作出
- 2014 - 2017 Anti-tumor mechanism of soluble form of sialic acid-recognizing protein, Siglec-9
- 2014 - 2016 組換え酵素Rad51と癌抑制タンパク質BRCA2の結合の種間比較に基づく分子創薬
- 2012 - 2014 Mechanisms of development of AIDS encephalopathy using a new transgenic mouse model expressing HIV-1 Nef
- 2011 - 2013 Tumorigenic effects of BRCA2 mutation and genomic instability in dogs
- 2010 - 2012 Biological function and gene regulation of epididymal-specific carboxylesterase (CES4)
- 2009 - 2011 Regulation Mechanisms of the body size in mice
- 2007 - 2009 Analysis of a novel NFkB inhibitor deficient mouse as a model for atopic dermatisis
- 2005 - 2006 Expression and role of sugar-recognition molecule galectin in the digestive tract
- 2005 - 2006 新規アトピー性皮膚炎原因遺伝子の機能解析
- 2003 - 2006 Molecular and clinical analysis for metastasis and invasion of cancers in small animals
- 2004 - 2005 ウシ肝cDNAマイクロアレイの評価と妊娠ウシ肝の特異発現遺伝子の検索
- 2003 - 2005 Regulation of host defense and development by innate-immunity signal transduction system
- 2003 - 2004 ジーンターゲティングによる新規アトピー性皮膚炎モデル動物の開発
- 2001 - 2003 Development of hantavirus vaccine and rapid diagnosis kit by using soluble recombinant envelope glycoproteins
- 1999 - 2001 DNA repair defect, tumorigensis, and hereditary breast cancer gene Brca2 -Studies in vitro and in vivo, and association with Rad51.
- 1999 - 2001 Study for the development of new gene targeting method utilizing epitope tags
- 1999 - 2000 Fundamental studies on the protective mechanisms of a novel serum lectin (CBPb01)
- 1999 - 1999 近赤外光を用いたイヌの脳活動の無侵襲計測 - イヌのこころの動きを測る
- 1997 - 1998 急性相タンパク質の新規動物資源生産管理および野生動物生態調査への応用
- 1995 - 1996 Neuroendocrine mechanism of stress-induced immunosuppression and roles of cytokines.
- 1995 - 1995 ウシ肝細胞における急性相タンパク質の遺伝子発現調節機構の解析
- 1994 - 1994 ウシハプトグロビン遺伝子の構造および転写調節機構の解析
- 1993 - 1994 Molecular mechanisms of the central actions of interleukin-1
- 1993 - 1993 ウシの初代培養肝細胞を用いた急性相タンパク質の遺伝子発現・合成調節機構の解析
- 炎症反応の制御に関わる細胞情報伝達機構
- 相同組換え反応の分子機構
- 家畜の急性相タンパク質の合成・分泌調節機構
- Signal transduction mechanisms in the inflammatory response
- Molecular mechanisms of homologous recombination.
- Mechanisms of the synthesis and secretion of acute-phase proteins in domestic animals.
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Papers (115):
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Keisuke Sato, Teppei Nakamura, Masami Morimatsu, Takashi Agui. Functional Analysis of Oligoadenylate Synthetase in the Emu (Dromaius novaehollandiae). Animals : an open access journal from MDPI. 2024. 14. 11
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Zida Zhu, Taisuke Kitano, Masami Morimatsu, Kazuhiko Ochiai, Toshina Ishiguro-Oonuma, Kosuke Oosumi, Xianghui Lin, Koichi Orino, Yasunaga Yoshikawa. A Highly Conserved Region in BRCA2 Suppresses the RAD51-Interaction Activity of BRC Repeats. Veterinary sciences. 2023. 10. 2
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Kei Shimakawa, Kazuhiko Ochiai, Sachi Hirose, Eri Tanabe, Masaki Michishita, Motoharu Sakaue, Yasunaga Yoshikawa, Masami Morimatsu, Tsuyoshi Tajima, Masami Watanabe, et al. Canine Mammary Tumor Cell Lines Derived from Metastatic Foci Show Increased RAD51 Expression but Diminished Radioresistance via p21 Inhibition. Veterinary sciences. 2022. 9. 12
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廣瀬 紗千, 落合 和彦, 岩崎 まりか[前田], 道下 正貴, 森松 正美, 田中 良和. p53四量体形成ドメイン変異イヌ乳腺腫瘍由来細胞株の性状解析. 日本獣医学会学術集会講演要旨集. 2022. 165回. [I1P-01]
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Marika Maeda, Kazuhiko Ochiai, Masaki Michishita, Masami Morimatsu, Hiroki Sakai, Nayuta Kinoshita, Motoharu Sakaue, Eri Onozawa, Daigo Azakami, Masami Yamamoto, et al. In vitro anticancer effects of alpelisib against PIK3CA-mutated canine hemangiosarcoma cell lines. Oncology reports. 2022. 47. 4
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MISC (73):
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望月 千尋, 上妻 創, 朱 子達, 北野 泰佑, 折野 宏一, 森松 正美, 吉川 泰永. がん抑制遺伝子BRCA2の新規転写調節機構の解明. 日本獣医学会学術集会講演要旨集. 2023. 166回. 184-184
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岡村 匡史, 森松 正美, 浅野 淳. AVMA動物の安楽死指針 2020年版の解説. LABIO 21. 2022. 87. 27-30
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吉川泰永, 森松正美, 上妻創, 折野宏一. 癌抑制遺伝子BRCA2の翻訳効率に影響を与えるスプライシングバリアント. 日本獣医学会学術集会講演要旨集. 2020. 163rd
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植村 光希, 落合 和彦, 森松 正美, 柏木 伸旭, 宇埜 友美子, 道下 正貴, 呰上 大吾, 小野沢 栄里, 近江 俊徳. イヌRAD51変異が複合体形成におよぼす影響の検討. 日本獣医学会学術集会講演要旨集. 2019. 162回. 479-479
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中沢綾香, 石黒(大沼)俊名, 落合和彦, 森松正美, 木崎景一郎. がん抑制遺伝子p53に変異を有するイヌ乳腺腫瘍細胞に対する血管新生阻害薬の抗腫瘍効果の解析. 日本獣医学会学術集会講演要旨集. 2019. 162nd
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Patents (5):
Lectures and oral presentations (135):
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乳廃用牛の医療応用 皮下埋植した鋳型内の低酸素環境は結合組織体の形成を誘導する
(日本バイオマテリアル学会大会予稿集 2023)
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エミューのオリゴアデニレート合成酵素の機能解析
(日本獣医学会学術集会講演要旨集 2023)
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コットンラットの胸腺にみられる嚢胞の由来と胸腺機能との関連
(日本獣医学会学術集会講演要旨集 2023)
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Medical Application of Dairy Waste Cattle-Hypoxic Condition Induces Dense Connective Tissue Formation in Subcutaneously Implanted Molds.
(日本バイオマテリアル学会大会予稿集(Web) 2023)
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がん抑制遺伝子BRCA2の新規転写調節機構の解明
(日本獣医学会学術集会講演要旨集 2023)
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Education (4):
- - 1992 Hokkaido University Graduate School of Veterinary Medicine
- - 1992 Hokkaido University Graduate School, Division of Veterinary Medicine
- - 1989 Hokkaido University Faculty of Veterinary Medicine
- - 1987 Hokkaido University School of Veterinary Medicine Veterinary Medicine
Professional career (1):
- PhD (Hokkaido University)
Work history (12):
- 2022/04 - 現在 Faculty of Veterinary Medicine Hokkaido University Laboratory of Laboratory Animal Science and Medicine Department of Applied Veterinary Sciences Professor
- 2013/11 - 2022/12 Faculty of Veterinary Medicine, Hokkaido University Attending Veterinarian of Animal Facility
- 2013/11 - 2022/03 Faculty of Veterinary Medicine, Hokkaido University Laboratory of Laboratory Animal Science and Medicine Department of Applied Veterinary Sciences Associate Professor
- 2012/04 - 2013/10 Institute for Genetic Medicine, Hokkaido University Laboratory of Animal Experiments Director
- 2008/07 - 2013/10 Institute for Genetic Medicine, Hokkaido University Disease Model Innovation Associate Professor
- 2007/04 - 2013/10 Institute for Genetic Medicine, Hokkaido University Laboratory of Animal Experiments Associate Professor
- 2005/10 - 2007/03 Institute for Genetic Medicine, Hokkaido University Laboratory of Animal Experiments Associate Professor
- 2004 - 2005 Graduate School of Medicine, Hokkaido University Laboratory of Histology and Cytology Assistant Professor
- 1997 - 2004 Faculty of Agriculture, Iwate University Laboratory of Physiology, Department of Veterinary Medicine Associate Professor
- 1996 - 1997 University of Texas MD Anderson Cancer Center Visiting Fellow
- 1992 - 1997 Graduate School of Veterinary Medicine, Hokkaido University Laboratory of Biochemistry Assistant Professor
- 1995 - 1995 University of São Paulo School of Medicine Visiting Fellow
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Committee career (13):
- 2024 - 現在 国立大学法人動物実験施設協議会 副会長
- 2023/02 - 現在 Editorial Board Member "Animals"
- 2022/06 - 現在 Japanese College of Laboratory Animal Medicine (JCLAM) Committee for Information Technology
- 2022/05 - 現在 Japanese Association for Laboratory Animal Science (JALAS) Assessment and Verification Committee
- 2022/05 - 現在 Japanese Association for Laboratory Animal Science (JALAS) Board of Directors
- 2022/04 - 現在 Japanese College of Laboratory Animal Medicine (JCLAM) Board of Directors
- 2022 - 現在 国立大学法人動物実験施設協議会 検証委員会委員
- 2020 - 現在 Japanese Association for Laboratory Animal Science (JALAS) Committee for the Act on Welfare and Management of Animals and its related matters
- 2020 - 現在 Japanese Association for Laboratory Animal Science (JALAS) Committee for Training System of Laboratory Animal Manager
- 2019/03 - 現在 Editorial Board Member of "Biomedical Research"
- 2018 - 現在 Japanese Association for Laboratory Animal Science (JALAS) Committee for laboratory animal welfare and ethics
- 2016 - 現在 Japanese Association for Laboratory Animal Science (JALAS) Committee for the Training of Site Visitors in Verification and Validation Programs for Proper Conduct of Animal Experimentations
- 2014 - 現在 Japanese Association for Laboratory Animal Medicine (JALAM) Board of Directors
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Association Membership(s) (13):
JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE SOCIETY OF VETERINARY SCIENCE
, The Japanese College of Laboratory Animal Medicine (JCLAM)
, The Japanese Association for Laboratory Animal Medicine (JALAM)
, JAPAN VETERINARY MEDICAL ASSOCIATION
, 日本実験動物医学専門医協会
, 日本実験動物医学会
, 日本実験動物学会
, 日本分子生物学会
, 日本生化学会
, 日本獣医学会
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