Jian Yao

ヤオジアン | Jian Yao

Affiliation and department：
Job title： Associate Professor

Research field (1)： Experimental pathology

Research keywords (1)： stress response, inflammatory response, renal pathophysiology, intercellular communication

Research theme for competitive and other funds (37)：

2020 - 2022 Role of gap junction protein connexin43 in B cell activation and lupus nephritis
2017 - 2020 TRPV4とコネクシン・パネキシン相互作用に着目した間質性膀胱炎の病態解明
2014 - 2017 新規低侵襲パーソナル3次元表皮の応用-アトピー性皮膚炎新規遺伝子異常の探索-
2014 - 2017 閉塞膀胱の病態におけるコネキシンヘミチャネルの役割
2014 - 2017 糸球体足細胞傷害におけるギャップ結合タンパクconnexin43の役割

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Papers (123)：

Mao Z, Huang Y, Li B, Tomoya K, Shinmori H, Zeng X, Gu Z, Yao J. Hydrogen sulfide as a potent scavenger of toxicant acrolein. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. 2022. 229. 113111
Yan Q, Mao Z, Hong J, Gao K, Niimi M, Mitsui T, Yao J. Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury. Antioxidants. 2021. 10. 7. 1007
Xiawen Yang, Zhimin Mao, Yanru Huang, Haizhao Yan, Qiaojing Yan, Jingru Hong, Jianglin Fan, Jian Yao. Reductively modified albumin attenuates DSS-Induced mouse colitis through rebalancing systemic redox state. Redox Biology. 2021. May. 41. 101881
Xiling Zhang, Zhimin Mao, Yanru Huang, Zhen Zhang, Jian Yao. Gap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca2+ and Ca2+-dependent regulation of TXNIP. Channels. 2020. 14. 1. 246-256
Jingru Hong, Jian Yao. Connexin Hemichannels Contribute to the Activation of cAMP Signaling Pathway and Renin Production. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020. 21. 12. 4462

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Lectures and oral presentations (10)：

Hydrogen Sulfide Is an Endogenous Scavenger of Lipid Oxidation Product Acrolein
(The 27th Annual Conference of the Society for Redox Biology and Medicine 2020)
Regulation of Antibody Activity by Pro- and Anti-oxidants via Modification of the Disulfide Bonds in Antibody Structure
(The 27th Annual Conference of the Society for Redox Biology and Medicine 2020)
Hydrogen Sulfide Determines Tumor Cell Sensitivity to Thioredoxin Inhibitor PX-12
(SfRBM2019 2019)
Connexin43 regulates inflammasome activation and inflammatory cell injury through modulation of NADPH Oxidase-dependent redox signaling pathway
(International Gap Junction Conference 2019 2019)
Hydrogen sulfide inhibits adramycin-initiated glomerular pococyte injury via interference of Trx/ASK1/P38 signaling
(ISN world conference of nephrology 2019)

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Professional career (2)：

Work history (9)：

2020/04/01 - 山梨大学山梨大学医学部附属病院病院教授
2003/09/01 - 山梨大学先端応用医学講座・分子情報伝達学部門准教授
2003/09/01 - 山梨大学先端応用医学講座・分子情報伝達学部門准教授 (2019.11~病院教授)
1998/07/16 - 2003/08/31 新潟大学医学部附属腎研究施設機能制御学分野助教
1997/07/16 - 1998/07/15 The University of Tennessee Department of Physiology and Biophysics Postdoctoral fellow

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