Rchr
J-GLOBAL ID:200901094952584750   Update date: Nov. 21, 2019

SHINOHARA Akira

シノハラ アキラ | SHINOHARA Akira
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.protein.osaka-u.ac.jp/genome/index.html
Research field  (2): Genetics/Genome dynamics ,  Molecular biology
Research theme for competitive and other funds  (3):
  • Studies on function of recombination gene, RAD51, in human and mouse
  • Biochemical characterization of yeast Rad51、Rad52 proteins
  • Molecular analysis of meiotic recombination
Papers (66):
  • Miki Shinohara, Douglas K Bishop and Akira Shinohara. Distinct Functions in Regulation of Meiotic Crossovers for DNA Damage Response Clamp Loader Rad24(Rad17) and Mec1(ATR) Kinase. Genetics. 2019. in press
  • Tomoko Takagi, Masako Osumi and Akira Shinohara. Nuclear actin cable with multiple branches during yeast meiosis. BioRxiv. 2019
  • Kiran Challa, M. Shinohara, Shinohara Akira. Meiotic prophase-like pathway for cleavage-independent removal of cohesin for chromosome morphogenesis. Current Genetics. 2019. 65. 4. 817-827
  • Kenichiro Matsuzaki, Shizuka Kondo, Tatsuya Ishikawa, and Akira Shinohara. Human RAD51 paralogue, SWSAP1, fosters RAD51 filament by regulating the anti-recombinase, FIGNL1 AAA+ ATPase. Nature Communications. 2019. 10. 1407
  • Hiroyuki Sasanuma, Hana Subhan M. Sakurai, Yuko Furihata, Kiran Challa, Lira Palmer, Susan M. Gasser, Miki Shinohara and Akira Shinohara. Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis. Chromosoma. 2019. in press
more...
MISC (13):
  • Terasawa M, Shinohara A, Shinohara M. Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability. Cancer science. 2014. 105. 12. 1519-1525
  • Tsurimoto T, Itoh T, Katayama T, Kimura H, Shinohara A. Report from the Working Group of the Molecular Biology Society of Japan for the investigation of fraud in research papers. Genes to cells : devoted to molecular & cellular mechanisms. 2009. 14. 8. 903-908
  • Shinohara M, Shinohara A. [Molecular mechanism of meiotic crossover formation]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2009. 54. 4 Suppl. 466-471
  • Shinohara A. [Mechanisms of recombination on chromosomes: overview]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2009. 54. 4 Suppl. 447-449
  • Shinohara A, Shinohara M. [Mechanism of DNA recombination ad chromosomal morphogenesis in the meiotic phase]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2008. 53. 11. 1315-1325
more...
Lectures and oral presentations  (16):
  • Control of cleavage-independent removal of meiosis-specific cohesin
    (International RecA and chromosome dynamics meeting, Taipei 2015)
  • Control of cleavage-independent removal of cohesin
    (FAOBMB meeting, Hyderabad, India 2015)
  • Control of cleavage-independent release of cohesin during meiosis
    (EMBO workshop on meiosis, Oxford, UK 2015)
  • Control of cleavage-independent removal of meiosis-specific cohesin
    (Chromosome stability meeting, Trivandrum, India 2016)
  • Control of cleavage-independent removal of meiosis-specific cohesin
    (Gordon Research Conference on Meiosis, New London, NH, USA 2016)
more...
Works (4):
  • Characterization of functional domains of E. coli RecA protein by intragenic suppressors
    1985 - 1989
  • Biochemical characterization of Rad52 protein
    1990 - 1993
  • Biochemical characterization of Rad51 protein from yeast.
    1993 -
  • Analysis of functions of RAD51 and DMC1 in meiosis
    1993 -
Education (5):
  • 1982 - 1986 Osaka Univ. School of Science Department of Biology
  • - 1986 Osaka University Faculty of Science
  • 1986 - 1988 Osaka University Graduate School of Science
  • 1988 - 1991 Osaka Univ. Graduate School of Science
  • - 1991 Osaka University Graduate School, Division of Natural Science
Professional career (2):
  • Ph.D. (Osaka University)
  • (BLANK)
Work history (4):
  • 1991 - 1993 Post-doctral fellow
  • 1999 - 2000 University of Chicago, Assistant Professor
  • 1993 - Osaka Univ. Faculty of Science, Research Associate
  • 2001 - Osaka Univ. Graduate School of Science, Assistant Prof.
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