- 2022 - 2025 抗腫瘍免疫の活性化を誘導し、AML薬剤治療の効果を増強させる分子の探索
- 2022 - 2024 膜のない構造体パラスペックルの生体内での役割と生物学的意義の解明を目指して
- 2020 - 2024 骨髄異形成症候群(MDS)の病態解明と治療戦略
- 2019 - 2024 Characterization of chromatin replication associated with stem cell fate decision
- 2018 - 2020 Analyses of relationship between clonal hematopoiesis associated with leukemia-related gene mutations and leukemia/solid tumors/cardiovascular diseases
- 2017 - 2019 Ab initio analysis on the pathophysiology of hematopoietic neoplasms
- 2017 - 2019 Analysis of relationship between clonal hematopoiesis and cell senescence
- 2016 - 2018 Crosstalk between epigenetic therapy and anti-tumor immunity in the treatment of hematopoietic neoplasms
- 2015 - 2018 Establishment and analysis of a mouse model of treatment-resistant autism comorbid with ADHD
- 2015 - 2018 Comprehensive elucidation of MDS (myelodysplastic syndromes) pathogenesis
- 2014 - 2017 Roles of AFF4, a member of the AF4 family of transcription factors, in FGF21 resistance
- 2014 - 2017 Analysis of the mechanisms by which mast cell activation is regulated by paired receptors LMIR3 and LMIR7
- 2014 - 2016 Functional relationship between cell fate decision and epigenetic control of gene expression of the chromosome
- 2010 - 2016 Control of cell fate decision in the cells differentiating to multiple pathways in a step-by-step fashion
- 2010 - 2015 Molecular mechanisms of cell fate determination in the cells that undergo stepwise differentiation to multiple pathways
- 2010 - 2015 Crosstalk between chromosome modification and transcription factors in the differentiation of hematopoietic cells
- 2011 - 2014 Integrative elucidation of molecular mechanisms for leukemogenesis: Identification and analyses of mutations with novel categories.
- 2011 - 2014 What is a ligand fro LMIR, regulating allery and inflammation?
- 2011 - 2012 Analysis of relationship between nuclear segmentation and gene expression using neutrophils and ATL cells
- 2011 - 2012 MgcRacGAPの分解機構:新しい細胞周期チェックポイント
- 2010 - 2012 Molecular mechanism of MLL-related leukemogenesis in a mouse modelfor generation of cancer stem cells
- 2010 - 2012 The kirrel family regulates neural circuits formation and higher brain functions.
- 2008 - 2010 Analysis of in vivo functions of LMIR3/4/5
- 2008 - 2010 Toward the comprehensive understanding of molecular mechanisms of hematopoietic malignancies
- 2009 - 2009 新規RacGAPの細胞癌化における機能解析
- 2008 - 2009 オンコジーン同定の新しい方法論の確立
- 2008 - 2009 ペア型免疫レセプターファミリーLMIR/CLM/MAIRの機能解析とリガンド同定
- 2008 - 2009 MgcRacGAPによる細胞周期と増殖分化の統合的調節機構の解析
- 2008 - 2009 シグナル伝達系阻害薬の同定と分子標的療法への応用
- 2007 - 2008 Roles of a novel kinetochore protein CENP-50 in the transcriptionalregulation and chromosome dividing
- 2007 - 2008 Regulation of self-renewal of leukemic stem cells by hematopoietic transcription factors
- 2006 - 2007 シグナルシークエンストラップ法を利用した新規癌マーカー抗体の作成
- 2006 - 2007 Analysis on the molecular mechanisms for the self renewal of the leukemic stem cells and for the leukemcgenesis
- 2006 - 2007 STAT3を標的とした分子標的療法をめざして
- 2005 - 2007 What is the function of integrin allb in mast cell?
- 2005 - 2006 Characterization of a novel kinetochore protein that are involved in cell growth and differentiation.
- 2005 - 2006 アポトーシス細胞を認識する新しいレセプターLMIR3/4の機能解析
- 2005 - 2006 造血ニッチを構成する膜蛋白質mkirreの機能解析
- 2004 - 2006 Crosstalk between STATs and small GTPases in the control of cell division and differentiation.
- 2005 - 2005 FLT3とSTAT3を標的とした分子標的療法をめざして
- 2004 - 2005 Regulation of self-renewal of hematopoietic stem cells by bone marrow stromal cells
- 2004 - 2005 Roles of a newly identified TNF receptor superfamily, TROY, in the nervous system
- 2004 - 2004 血球貪食症候群の病態形成におけるoncostatin Mの役割
- 2004 - 2004 マスト細胞活性化調節に関与する新しいレセプター群の機能解析
- 2004 - 2004 転写因子をターゲットとした分子標的療法をめざして
- 2003 - 2004 霊長類ES細胞維持因子の同定とその機能解析
- 2002 - 2003 冠動脈および大動脈の血管内皮に発現する新規接着分子の解析
- 2002 - 2003 Analysis of hematopoietic lineage plasticity by using inducible transcription factors
- 2001 - 2003 Identification of molecules involved in inactivation of mast cells.
- 2003 - 白血病と骨髄異型性疾患の分子基盤
- 2003 - Molecular basis of leukemia and MDS
- 2001 - 2002 Pleiotropic functions of cytokines and STAT5
- 2001 - 2002 Th2細胞優位に発現されるサイトカインレセプターδ1の解析
- 2001 - 2001 シグナル伝達分子に対する特異的阻害剤の同定と白血病・癌に対する治療への応用
- 2001 - 2001 慢性骨髄性白血病発症の分子メカニズムの解明
- 2001 - 2001 MgcRacGAP/Cyk4によるサイトキネシス制御と細胞分化・増殖
- 1998 - 2001 造血細胞の遺伝子操作
- 2000 - 2000 マウスホモロガスリコンビナーゼの遺伝子クローニング
- 2000 - 2000 シグナル伝達分子に対する特異的阻害剤の同定および白血病に対する治療法への応用
- 2000 - 2000 自己免疫病誘導モデルを用いた、病態形成に関与する遺伝子の疾患誘導能の解析
- 2000 - 2000 TH2細胞優位に発現される新規サイトカインレセプターの解析
- 1999 - 2000 Trial of cloning and functional analysis of a novel vascular endothelial growth factor.
- 1998 - 2000 Novel expression cloning methods based on retrovirus mediated gene transfer.
- 1999 - 1999 恒常的活性型サイトカインレセプターおよび恒常的活性型転写因子の造腫瘍性の検討
- 1997 - 1999 Activation of cytokine signaling by constitutively active STAT5.
- 1997 - 1999 Development of human disease model system using small nonhuman primate
- 1999 - サイトキネシスに関与する新規GAP分子MgcRacGAP
- 1999 - MgcRacGAP is involved in cytokinesis
- 1998 - 1998 レトロウイルスベクターによる造血幹細胞への遺伝子導入とその応用
- 1997 - 1998 レトロウイルスcDNA発現ライブラリーによる未知のヒト白血病原因遺伝子の探索
- 1997 - 1997 レトロウイルスcDNA発現ライブラリーによる新規サイトカイン遺伝子の単離
- 1994 - レトロウイルスを利用した発現スクリーニング法
- 1994 - Retrovirus-Mediated Expression Screening
- 1990 - サイトカインレセプターのシグナル伝達
- 1990 - Signal transduction of Cytokine Receptor
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