Art

J-GLOBAL ID：202002220259621071   Reference number：20A1949665

PD-L1/L2 protein levels rapidly increase on monocytes via trogocytosis from tumor cells in classical Hodgkin lymphoma

PD-L1/L2蛋白質レベルは古典的ホジキンリンパ腫の腫瘍細胞からのトロゴサイトーシスを介して単球に急速に増加する【JST・京大機械翻訳】

Author (28)： Kawashima Masaharu (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Kawashima Masaharu (Division of Clinical Oncology and Hematology, Jikei University School of Medicine, Minato-ku, Tokyo, Japan) ,  Carreras Joaquim (Department of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, Japan) ,  Higuchi Hiroshi (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Higuchi Hiroshi (Research Institute of Science and Technology, Tokai University, Hiratsuka, Kanagawa, Japan) ,  Kotaki Ryutaro (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Hoshina Takahiro (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Hoshina Takahiro (Division of Cellular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan) ,  Okuyama Kazuki (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Suzuki Naoto (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Suzuki Naoto (Department of Biosciences, School of Science, Kitasato University, Sagamihara, Kanagawa, Japan) ,  Suzuki Naoto (Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan) ,  Kakizaki Masatoshi (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Miyatake Yuji (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Ando Kiyoshi (Department of Hematology and Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan) ,  Nakayama Masafumi (Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Aoba-ku, Sendai, Japan) ,  Umezu Shinjiro (Department of Modern Mechanical Engineering, Waseda University, Shinjuku-ku, Tokyo, Japan) ,  Horie Ryouichi (Division of Hematology, Department of Laboratory Sciences, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, Japan) ,  Higuchi Yuriko (Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan) ,  Katagiri Koko (Department of Biosciences, School of Science, Kitasato University, Sagamihara, Kanagawa, Japan) ,  Goyama Susumu (Division of Cellular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan) ,  Kitamura Toshio (Division of Cellular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan) ,  Chamoto Kenji (Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Yano Shingo (Division of Clinical Oncology and Hematology, Jikei University School of Medicine, Minato-ku, Tokyo, Japan) ,  Nakamura Naoya (Department of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, Japan) ,  Kotani Ai (Department of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Kanagawa, Japan) ,  Kotani Ai (Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Saitama, Japan) ,  Kotani Ai (AMED-PRIME, Japan Agency for Medical Research and Development, Tokyo, Japan)
Material： Leukemia
Volume： 34  Issue： 9  Page： 2405-2417  Publication year： 2020 
JST Material Number： W4691A  ISSN： 0887-6924  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: In classical Hodgkin...

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Thesaurus term： fluorescent antibody technique ,  *tumor cell ,  T cell ,  characterization ,  *monocyte ,  *Hodgkin disease ,  Up-Regulation ,  Antigen Presentation ,  tumorigenesis ,  coculture ,  *Antigens, CD274 ,  Tumor-Associated Macrophages ,  bioassay

JST classification (3)： Blood cell tumors(=neoplasms)  (GK04000M) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Terms in the title (6)： PD-L1 ,  蛋白質レベル ,  ホジキンリンパ腫 ,  腫瘍細胞 ,  トロゴサイトーシス ,  単球