Yaginuma Yuji

ヤギヌマユウジ | Yaginuma Yuji

Affiliation and department：

Research field (2)： Obstetrics and gynecology , Experimental pathology

Research keywords (8)：分子生物学 , 発癌 , 実験病理学 , 子宮頸癌 , 子宮体癌 , 卵巣癌 , Pathology , Obstetrics & Gynecology

Research theme for competitive and other funds (9)：

2019 - 2023 食道癌におけるトランスフェリン受容体の機能解明と分子標的薬の探索
2008 - 2010 Mechanism of rapamycin-resistant translation in mouse hepatocellular carcinoma cells
1997 - 1999 Molecular cloning of candidate gene for human ovarian carcinogenesis
1997 - 1998 細胞老化,不死化に関与する遺伝子の探索
1996 - 1997 Relaxation of IGF2 Imprinting in Human Gynecologic Tumors

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Papers (50)：

Masafumi Yoshimoto, Aoi Tokuda, Ayami Eguchi, Yoshihiro Nozawa, Tsutomu Mori, Yuji Yaginuma. Alterations of UHRF family Expression and was regulated by High Risk Type HPV16 in Uterine Cervical Cancer. Experimental Cell Research. 2024. 437. 1-8
Masafumi Yoshimoto, Aoi Tokuda, Ayami Eguchi, Yoshihiro Nozawa, Tsutomu Mori, Yuji Yaginuma. Alterations of UHRF family expression and UHRF1/ICBP90 inhibits PTEN expression in endometrial cancer. Oncology. 2023. 101. 457-468
Ryutaro Kajihara, Tadahiro Numakawa, Haruki Odaka, Yuji Yaginuma, Noemi Fusaki, Toshika Okumiya, Hirokazu Furuya, Seiji Inui, Takumi Era. Novel Drug Candidates Improve Ganglioside Accumulation and Neural Dysfunction in GM1 Gangliosidosis Models with Autophagy Activation. Stem cell reports. 2020. 14. 5. 909-923
Yaginuma Yuji, Yoshimoto Masafumi, Tokuda Aoi. USP15 inhibits HPV16 E6 degradation and catalytically inactive USP15 has reduced inhibitive activity. Acta irologica. 2018. 62. 2. 147-156
Yoshimoto Masafumi, Tokuda Aoi, Nishiwaki Kunihiko, Sengoku Kazuo, Yaginuma Yuji. Abnormal Expression of PICT-1 and its Codon 389 Polymorphism is a Risk Factor for Human Endometrial Cancer. Oncology. 2018. 95. 43-51

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MISC (26)：

Genki Takayama, Shinnosuke Nambu, Yuji Yaginuma. Major Molecules Associated with Iron Metabolism. Bulletin of Kumamoto University, School of Health Sciences. 2022. 18. 1-8
Genki Takayama, Shinnosuke Nambu, Yuji Yaginuma. Iron Metabolism in Malignant Tumors. Bulletin of Kumamoto University, School of Health Sciences. 2022. 18. 9-17
Shinnosuke Nambu, Genki Takayama, Yuji Yaginuma. Efficacy, Immunogenicity, and Safety of Cervical Cancer Vaccine. Bulletin of Kumamoto University, School of Heakth Sciences. 2022. 18. 18-26
Shinnosuke Nambu, Genki Takayama, Yuji Yaginuma. HPV infection and cervical cancer vaccine use in Japan. Bulletin of Kumamoto University, School of Heakth Sciences. 2022. 18. 27-36
曽我美南, 梶原隆太郎, 沼川忠広, 小高陽樹, 柳沼裕二, 房木ノエミ, 奥宮敏可, 古谷博和, 乾誠治, 江良択実. ガングリオシドーシス由来神経細胞の新しい異常表現型とそれを使った薬剤開発. 日本先天代謝異常学会雑誌. 2021. 37. 140-140

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Books (9)：

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Lectures and oral presentations (64)：

Alteration of UHRF Family, NIRF and ICBP90 in Endometrial Cancer
(2017)
Codon 389 Polymorphism and Down-regulation of PICT-1/GLTSCR2 is Correlated with Ovarian Cancer
(2017)
USP15 inhibits HPV16 E6 degradation and catalytically inactive USP15 has reduced inhibitive activity
(2017 AACR annual meeting 2017)
Te PICT-1 is Required for USP7 to Effectively Stabilize p53 Protein, and Codon 389 Polymorphism is a Risk Factor for Ovarian Cancer
(2017 AACR annual meeting 2017)
婦人科悪性腫瘍の発生機序ー子宮内膜症の癌化を含めてー
(第二回札幌Women's Health懇話会 2016)

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Education (2)：

Professional career (1)：

Work history (5)：

2010/04 - 現在 Graduate School of Health Sciences, Faculty of Life Sciences, Kumamoto University Department of Oncology Professor
2007/01 - 2010/03 Asahikawa Medical University Department of Tumor Pathology Associate Professor
2000/10 - 2006/12 Asahikawa Medical University 1st Department of Pathology Associate Professor
1992/04 - 2000/09 Asahikawa Medical University Department of Obstetrics & Gynecology Assisitant Professor
1989/04 - 1992/03 NIH visiting fellow

Association Membership(s) (4)：

日本病理学会 , 日本癌学会 , 日本産婦人科学会 , アメリカ癌学会(AACR)

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