Research theme for competitive and other funds (16)：
2015 - 2019 Funnel-gas model for studying protein complex formations under crowded environment
2009 - 2014 Analysis on the structural polymorphism of IDPs by computer simulation
2008 - 2010 Research of flow-mechanism in traffic and self-driven particles systems
2005 - 2006 Theoretical Study on Phase Space Landscapes Acquired by Evolution
2003 - 2005 Dynamical properties of traffic flow -Data analyses and simulation-
2001 - 2002 Structural Characteristics of evolutionally developed phase spaces of ecosystems and proteins
1999 - 2000 Dynamics and Logic in Evolutions of Ecosystems and Proteins
1998 - 1998 量子ラチェットの基礎的研究
1996 - 1996 メタダイナミクスを取り入れた自律的発展系における創発的進化の研究
1996 - 1996 混合高分子溶融体系の秩序構造
1995 - 1995 非線形動力学の立場から見た交通流とカオス
1995 - 1995 混合高分子溶融体系の秩序構造
1994 - 1994 統計的依存時間の方法による臨界緩和スペクトラム
1993 - 1993 相転移のモンテカルロシミュレーションへのベイズ推定の応用
1989 - 1990 Electronic State and Many-body Effect in Transition and Typical Element Systems
1989 - 1989 遷移元素酸化物の電子状態と超伝導のモデル
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Papers (128)：
Macoto Kikuchi. Phenotype selection due to mutational robustness. PLOS ONE. 2024. 19. 11. e0311058-e0311058
Macoto Kikuchi. Quantitative Analysis for Evolution of Mutational Robustness and Bistability: Use of a Rare-Event Sampling Method. 2022. 62. 6. 360-364
Tadamune Kaneko, Macoto Kikuchi. Evolution enhances mutational robustness and suppresses the emergence of a new phenotype: A new computational approach for studying evolution. PLOS Computational Biology. 2022. 18. 1. e1009796-e1009796
Shintaro Nagata, Macoto Kikuchi. Emergence of cooperative bistability and robustness of gene regulatory networks. PLOS Computational Biology. 2020. 16. 6. e1007969-e1007969
A.Nakayama, M.Kikuchi, A.Shibata, Y.Sugiyama, S.Tadaki, S.Yukawa. Scaling from Circuit Experiment to Real Traffic Based on Optimal Velocity Model. Traffic and Granular Flow '15. 2016. 523-530
Macoto Kikuchi, Yoshikatsu Tada, Nobu C. Shirai. Funnel GAS Model for Protein Many-Body Systems under the Crowded Environment. BIOPHYSICAL JOURNAL. 2018. 114. 3. 200A-200A
Nobu C. Shirai, Macoto Kikuchi. The Interplay of Intrinsic Disorder and Macromolecular Crowding on alpha-Synuclein Fibril Formation. BIOPHYSICAL JOURNAL. 2016. 110. 3. 552A-552A
Macoto Kikuchi, Ryo Kanada, Fumiko Takagi. Allosterically Regulated Structural Fluctuation and Microtubule-Binding Affinity of KiF1A-A Simulation Study of Coarse-Grained Model -. BIOPHYSICAL JOURNAL. 2016. 110. 3. 459A-459A
Matsushita Katsuyoshi, Sugihara Hidetoshi, Kikuchi Macoto, Nogawa Tomoaki, Sasaki Munetaka. 30aPS-107 Examination of Energy Landscape Funnelizing in Coupled Folding and Binding. Meeting abstracts of the Physical Society of Japan. 2014. 69. 1. 425-425
Phenotype Selection due to Mutational Robustness in a Model of Gene Regulatory Networks
(International Conference on Biological Physics 2023)
Non-equilibrity of evolution revealed by multicanonical ensemble method: Phenotype selection due to mutational robustness in gene regulatory networks
(STATPHYS28 2023)
Genotypic entropy and bias in evolution of gene regulatory networks
(Statistical Physics and Information Processing in Living Systems 2023)
Phenotype Selection Due To Mutational Robustness: A Computational Study
(Biophysical Society Meeting 2023 2023)
Use of Multicanonical Monte Carlo Method for Exploring Mutational Robustness of Gene Regulatory Network
(Conference on Computational Physics 2022 2022)
Professional career (1)：
理学博士
Work history (7)：
2024/04 - 現在 D3 Center, Osaka University Invited professor
2000/04 - 2024/03 Osaka University Cybermedia Center Professor
2000/01 - 2000/03 Osaka University Graduate School of Science
1996/04 - 1999/12 Osaka University Graduate School of Science
1993/08 - 1996/03 Osaka University School of Science
1987/02 - 1993/07 Osaka University School of Science
1991/09 - 1993/03 Max Planck institute for polymer Max Planck fellow
