J-GLOBAL ID:201101047898581341   Update date: Oct. 19, 2020

Naoki Umemura

ウメムラ ナオキ | Naoki Umemura
Affiliation and department:
Job title: 講師
Research field  (5): Surgical dentistry ,  Oral medicine ,  Conservative dentistry and endodontics ,  Pharmacology ,  Oral medicine
Research keywords  (2): 歯髄幹細胞 ,  多血小板血漿
Research theme for competitive and other funds  (8):
  • 2020 - 2023 歯髄幹細胞の象牙芽細胞への分化誘導メカニズムの歯科臨床応用
  • 2017 - 2020 Clarification of metastasis development mechanism in oral cancer stem cell
  • 2017 - 2019 低酸素環境下における口腔癌のがん幹細胞に対する新規分子標的治療の開発
  • 2014 - 2017 Mechanism of multidrug resistance caused after the treatment targeting CD44, and the strategy for overcoming the resistance in head and neck squamous cell carcinoma.
  • 2014 - 2017 Analysis of PI3-kinase/Akt signaling on the osteogenesis of dental pulp stem cells in human.
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Papers (39):
  • Naoki Umemura, Masahiro Sugimoto, Yusuke Kitoh, Masanao Saio, Hiroshi Sakagami. Metabolomic profiling of tumor-infiltrating macrophages during tumor growth. Cancer immunology, immunotherapy : CII. 2020
  • Morimoto-Ito H, Mizuno-Kamiya M, Umemura N, Inagaki Y, Takayama E, Kawaki H, Muramatsu Y, Sumitomo S, Kondoh N. Immunosuppressive effect of mesenchymal stromal cells is enhanced by IL-1α from oral squamous cell carcinoma cells. The Open Dentistry Journal. 2019. 13. 1. 221-227
  • Junko Masuda, Eiji Takayama, Tatsuo Ichinohe, Warren Strober, Masako Mizuno-Kamiya, Tomokatsu Ikawa, Atsushi Kitani, Harumi Kawaki, Ivan Fuss, Hiroshi Kawamoto, et al. Suppression effect on IFN-γ of adipose tissue-derived mesenchymal stem cells isolated from β2-microglobulin-deficient mice. Experimental and therapeutic medicine. 2018. 16. 5. 4277-4282
  • Sumi S, Umemura N, Adachi M, Ohta T, Naganawa K, Kawaki H, Takayama E, Kondoh N, Sumitomo S. The luminance ratio of autofluorescence in a xenograft mouse model is stable through tumor growth stages. Clinical and experimental dental research. 2018. 4. 5. 174-181
  • Gul HI, Tugrak M, Gul M, Sakagami H, Umemura N, Anil B. Synthesis and Cyototoxicities of New Azafluorenones with Apoptotic Mechanism of Action and Cell Cycle Analysis. Anti-cancer agents in medicinal chemistry. 2018
MISC (13):
  • Nobuo Kondoh, Masako Mizuno-Kamiya, Naoki Umemura, Eiji Takayama, Harumi Kawaki, Kenji Mitsudo, Yasunori Muramatsu, Shinichiro Sumitomo. Immunomodulatory aspects in the progression and treatment of oral malignancy. The Japanese dental science review. 2019. 55. 1. 113-120
  • 梅村直己, 上野恭平, 川木晴美, 高山英次, 近藤信夫. 腫瘍内浸潤マクロファージの細胞内代謝は腫瘍の腫瘍の増大に伴い解糖系が亢進する. Journal of Oral Biosciences Supplement (Web). 2019. 2019. 328 (WEB ONLY)
  • 鷲見 成紀, 梅村 直己, 足立 誠, 太田 貴久, 長縄 鋼亮, 川木 晴美, 高山 英次, 近藤 信夫, 住友 伸一郎. 口腔がん診断の自然蛍光画像診断の輝度比率は腫瘍の増大に影響せず安定している. Journal of Oral Biosciences Supplement. 2018. 2018. 243-243
  • Naoki Umemura, Emika Ohkoshi, Hiroshi Sakagami. CD44-targeted chemotherapy inhibits tumor recurrence in head and neck squamous cell carcinoma. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2014. 34. S61-S61
  • Umemura Naoki, Emika Ohkoshi, Toshiyuki Nanbu, Jyun Shimada, Hiroshi Sakagami. Cancer Stem Cells targeting Chemotherapy in Head and Neck squamous cell carcinoma. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 97P-97P
Education (2):
  • 2004 - 2008 Gifu university
  • - 2002 Aichi-gakuin university
Professional career (1):
  • Ph.D (Gifu university)
Work history (3):
  • 2014 - Meikai University School of Dentistry
  • 2011/04 - Meikai University School of dentistry assistant professor
  • 2009/04 - 2011/03 University of Pittsburgh research associate
Committee career (2):
  • 2020/10 - 現在 Oncology Reports (Spandidos publications) Editorial Board member
  • 2020/04 - 現在 Molecular Medicne Reports (Spandidos publications) Editorial Board member
Awards (1):
  • 2008/10 - The 10th International Symposium on Dendritic Cells poster award
Association Membership(s) (5):
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