Rchr
J-GLOBAL ID:201301014923715403   Update date: Jun. 07, 2024

Akagi Jun-ichi

アカギ ジュンイチ | Akagi Jun-ichi
Affiliation and department:
Job title: 主任研究官
Research field  (3): Pharmaceuticals - health and biochemistry ,  Cell biology ,  Molecular biology
Research keywords  (6): Nanomaterials ,  Food safety ,  Genotoxicity ,  Mutagenesis ,  DNA repair ,  Translesion synthesis
Research theme for competitive and other funds  (12):
  • 2024 - 2027 Analysis of mutagenicity of stable deoxyadenosine adducts produced by exposure to acrylamide
  • 2024 - 2026 Research on safety assessment of novel nanomaterials for food, food containers and packaging
  • 2023 - 2024 食品及び食品用容器包装に使用されるナノマテリアル等の新規素材の安全性評価に関する研究
  • 2020 - 2023 食品及び食品用容器包装に使用される新規素材の安全性評価に関する研究
  • 2019 - 2022 Molecular mechanism of acrylamide-induced mutagenesis via translesion synthesis
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Papers (35):
  • Jun-ichi Akagi, Young-Man Cho, Takeshi Toyoda, Yasuko Mizuta, Kumiko Ogawa. EpCAM and APN expression in combination with γ-H2AX as biomarkers for detecting hepatocarcinogens in rats. Cancer Science. 2023
  • Jun-ichi Akagi, Masayuki Yokoi, Yumi Miyake, Tsuyoshi Shirai, Tomohiro Baba, Young-Man Cho, Fumio Hanaoka, Kaoru Sugasawa, Shigenori Iwai, Kumiko Ogawa. A formamidopyrimidine derivative from the deoxyguanosine adduct produced by food contaminant acrylamide induces DNA replication block and mutagenesis. Journal of Biological Chemistry. 2023. 105002
  • Jun-ichi Akagi, Yasuko Mizuta, Hirotoshi Akane, Takeshi Toyoda, Kumiko Ogawa. Oral toxicological study of titanium dioxide nanoparticles with a crystallite diameter of 6 nm in rats. Particle and Fibre Toxicology. 2023. 20. 1. 23-23
  • Takeshi Toyoda, Mizuki Sone, Kohei Matsushita, Hirotoshi Akane, Jun-Ichi Akagi, Tomomi Morikawa, Yasuko Mizuta, Young-Man Cho, Kumiko Ogawa. Early detection of hepatocarcinogens in rats by immunohistochemistry of γ-H2AX. The Journal of toxicological sciences. 2023. 48. 6. 323-332
  • Takanori Yamada, Takeshi Toyoda, Kohei Matsushita, Young-Man Cho, Jun-ichi Akagi, Tomomi Morikawa, Yasuko Mizuta, Kumiko Ogawa. Expression of stem cell markers as useful complementary factors in the early detection of urinary bladder carcinogens by immunohistochemistry for γ-H2AX. Archives of toxicology. 2021. 95. 2. 715-726
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MISC (49):
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Lectures and oral presentations  (50):
  • グリシドアミド付加体のホルムアミドピリミジン誘導体は DNA複製阻害と突然変異を誘発する
    (日本薬学会第144年会 2024年3月31日 2024)
  • 結晶子径が異なる二酸化チタン粒子のラットを用いた90日間反復経口投与による毒性影響とチタン蓄積の検討
    (第40回日本毒性病理学会学術集会 2024)
  • 食品汚染物質アクリルアミドの活性代謝物により生じるホルムアミドピリミジン誘導体の突然変異誘発機構
    (第46回日本分子生物学会年会 2023)
  • 90-day repeated oral toxicological study of titanium dioxide nanoparticles with a crystallite diameter of 6 nm in rats
    (The 50th Annual Meeting of the Japanese Society of Toxicology 2023)
  • Repeated oral toxicity study of anatase titanium dioxide nanoparticles with a crystallite diameter of 6 nm
    (2023)
more...
Professional career (1):
  • 博士(薬学) (大阪大学)
Work history (4):
  • 2010/10 - 現在 National Institute of Health Sciences
  • 2009/03 - 2010/09 Gakushuin University Faculty of Life Sciences, Department of Sciences Postdoc
  • 2009/05 - 2009/08 State University of New York at Stony Brook School of Medicine Pharmacological Sciences Visiting Scholar
  • 2007/04 - 2009/03 Kobe University Biosignal Research Center Postdoc
Awards (2):
  • 2021/01 - Japanese Society of Toxicologic Pathology JTP Achievement Award Size-dependent acute toxicity of silver nanoparticles in mice
  • 2017/09 - Division of Regulatory Sciences, The Pharmaceutical Society of Japan Regulatory science forum for young scientists responsible for the next generation Excellent presentation award
Association Membership(s) (5):
The Japanese Society of Toxicology ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  Japanese Society of Toxicologic Pathology ,  THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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