Research field (3)：
Food sciences
, Nutrition and health science
, Medical biochemistry
Research keywords (5)：
Biology of longevity
, mitochondria
, mTOR
, lifespan
, aging
Research theme for competitive and other funds (2)：
2020 - 2023 Mechanisms of mitochondrial disease suppression and lifespan extension by lactic acid bacteria
2012 - 2014 Role of CDC42 in pro-inflammatory phenotype of senescent vascular endothelial cells
Papers (39)：
Alessandro Bitto, Anthony S Grillo, Takashi K Ito, Ian B Stanaway, Bao M G Nguyen, Kejun Ying, Herman Tung, Kaleb Smith, Ngoc Tran, Gunnar Velikanje, et al. Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh syndrome. Nature metabolism. 2023. 5. 6. 955-967
Kosuke Hashimoto, Soichiro Ide, Mayumi Arata, Akiko Nakata, Akihiro Ito, Takashi K Ito, Norio Kudo, Bangzhong Lin, Kazuto Nunomura, Keiko Tsuganezawa, et al. Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors. ACS medicinal chemistry letters. 2022. 13. 7. 1077-1082
Takashi K. Ito, Tomohito Sato, Yusuke Takanashi, Zinat Tamannaa, Takuya Kitamoto, Keiichi Odagiri, Mitsutoshi Setou. A single oral supplementation of nicotinamide within the daily tolerable upper level increases blood NAD+ levels in healthy subjects. Translational Medicine of Aging. 2021. 5. 43-51
