Research keywords (5)：
simulation
, protein design
, protein structure
, protein
, biochemistry
Research theme for competitive and other funds (9)：
2024 - 2029 物理化学とデータ科学によるゼロからのタンパク質デザイン
2022 - 2025 多様な形状の新規回転対称多量体タンパク質の合理デザイン
2023 - 2024 Elucidation of glycosylation rules through de novo protein design
2018 - 2023 生体発動分子の創成:自然界の生体分子の改造とゼロからの設計
2019 - 2022 物理的に設計可能な蛋白質フォールド空間の解明:理論と実験的検証
2018 - 2019 タンパク質構造の合理的安定化手法の開発:βグルコシダーゼの耐熱化
2017 - 2019 Design of protein structure topology not existing on earth
2015 - 2019 Design Principle of Motor protein, F1-ATPase
2014 - 2017 細胞機能の制御・設計に向けたアロステリックタンパク質の人工設計
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Papers (30)：
Nobuyasu Koga, Rie Tatsumi-Koga. Inventing Novel Protein Folds. Journal of molecular biology. 2024. 168791-168791
Koya Sakuma, Naohiro Kobayashi, Toshihiko Sugiki, Toshio Nagashima, Toshimichi Fujiwara, Kano Suzuki, Naoya Kobayashi, Takeshi Murata, Takahiro Kosugi, Rie Tatsumi-Koga, et al. Design of complicated all-α protein structures. Nature Structural and Molecular Biology. 2024. 31. 2. 275-282
Takahiro Kosugi, Tatsuya Iida, Mikio Tanabe, Ryota Iino, Nobuyasu Koga. Design of allosteric sites into rotary motor V1-ATPase by restoring lost function of pseudo-active sites. Nature chemistry. 2023
Masaya Mitsumoto, Kanna Sugaya, Kazuki Kazama, Ryosuke Nakano, Takahiro Kosugi, Takeshi Murata, Nobuyasu Koga. State-Targeting Stabilization of Adenosine A2A Receptor by Fusing a Custom-Made De Novo Designed α-Helical Protein. International journal of molecular sciences. 2021. 22. 23
The era of designing proteins completely from scratch
2022
Protein design from zero toward tailor-made creation of our desired proteins
Kagaku 2016
SEITAI NO KAGAKU
Igakushoin 2014
Single molecule bio measuring: revolution technology exploring life system based on molecule
kagaku dojin 2014
Experimental Medicine
Yodosh 2013
Lectures and oral presentations (66)：
Design of Proteins with Various Shapes
(The 24th Annual Meeting of the Protein Science Society of Japan, Workshop on Molecular design for expanding protein functions -challenges and Prospects- 2024)
Design of proteins from scratch and the number of foldable topologies
(R022 Committee on Quantum Structural Biology 14th Meeting 2024)
Design of Proteins with Various Shapes
(ISBC2024, The 3rd International Symposium on Biofunctional Chemistry 2024)
Creation of novel proteins by rational design
(Cooperative Education and Research Center for Ubiquitous Green Chemical Energy 14th symposium, Niigata University Core Station 2024)
Design of protein structures from scratch: The number of possible topologies ?
(The 20th ABC-InFO Lecture and Networking 2024)
2003 - 2006 Kobe University Graduate School of Science and Technology Ph.D. in Department of Molecular Science
Professional career (1)：
Ph.D. (Kobe University)
Work history (12)：
2022/10 - 現在 Osaka University Institute for Protein Research (IPR) Professor
2022/10 - 現在 National Institutes of Natural Sciences, Exploratory Research Center on Life and Living Systems Protein Design Group Professor (Concurrent post)
2022/10 - 2023/09 Institute for Molecular Science Research Center of Integrative Molecular Systems Professor
2018/04 - 2022/09 Institute for Molecular Science Center for Integrative Molecular Systems Associate Professor
2018/04 - 2022/09 National Institutes of National Sciences, Exploratory Research Center on Life and Living Systems Protein Design Group Associate Professor
2014/04 - 2018/03 Institute for Molecular Science Research Center for Integrative Molecular Systems Associate Professor
2014/04 - 2017/03 PRESTO Design and Control of Cellular Functions
2009/07 - 2014 University of Washington Department of Biochemistry Senior Fellow
2007/07 - 2009/06 University of Washington Department of Biochemistry JSPS Postdoctoral Fellow for Research Abroad
2007/04 - 2007/06 Kyoto University Department of Biophysics, Graduate School of Science Postdoc
2006/04 - 2007/03 Kobe University Department of Chemistry, Faculty of Science Postdoc
2003/04 - 2006/03 Kobe University Faculty of Science JSPS Predoctoral Research Fellow (DC1)
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Committee career (3)：
2015/01 - 現在 日本生物物理学会 分野別専門委員
2023/06 - 2025/05 日本生物物理学会 代議員
2022/04 - 2024/03 The Biophysical Society of Japan SEIBUTSU BUTSURI, Editorial Board Member
Awards (4)：
2024/04 - Ministry of Education, Culture, Sports, Science and Technology, Japan Awards for Science and Technology: Research Category, The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology
2018/08 - 公益信託 分子科学研究奨励森野基金 分子科学研究奨励森野金
2013/10 - Biophysical Society of Japan Award for Young Investigator
2013/06 - Protein Society in Japan Award for Young Investigator
Association Membership(s) (3)：
The Protein Society
, PROTEIN SCIENCE SOCIETY OF JAPAN
, THE BIOPHYSICAL SOCIETY OF JAPAN
