Rchr
J-GLOBAL ID:201401019560014598
Update date: Aug. 17, 2024
Nishi Eiichiro
ニシ エイイチロウ | Nishi Eiichiro
Affiliation and department:
Research field (3):
Pharmacology
, Pathobiochemistry
, Internal medicine - General
Research theme for competitive and other funds (32):
- 2020 - 2023 多機能プロテアーゼによる血小板産生機構と急性冠症候群における意義
- 2020 - 2023 Investigation of the mechanisms by which Multifaceted Homeostasis is maintained by Nardilysin
- 2020 - 2022 Mechanism of protein secretion by physical stimuli (turbulent) and its physiological significance
- 2019 - 2022 A metalloprotease regulates the activity of the nuclear receptor REV-ERBs
- 2018 - 2021 Serum biomarkers affecting energy metabolism and body composition in Crohn's disease
- 2018 - 2020 新規肝栄養センサー分子による熱産生制御ネットワークの検討
- 2017 - 2020 Investigation on the homeostatic regulation by NRDC-p53 axis
- 2016 - 2019 A metalloprotease regulates the circadian clock
- 2016 - 2019 Elucidation of the mechanisms of neoatherosclerosis and degenerative vascular disease and development of novel therapeutic strategy
- 2016 - 2018 Investigation of the transcriptional coregulator involved in crosstalk between histone acetylation and methylation
- 2015 - 2017 Nardilysin regulates sinus automaticity through transcription of HCN.
- 2014 - 2017 Investigation of the multifaceted roles of nardilysin in homeostatic maintenance
- 2014 - 2016 エネルギー代謝と転写制御をつなぐ新規ヒストンコードリーダーに関する研究
- 2014 - 2016 Regulatory role of a histone-binding peptidase in inflammatory diseases
- 2013 - 2016 Elucidation of the mechanism of neoatherosclerosis
- 2013 - 2015 Assessment of temperature compensation of circadian rhythm by using cold-blooded mice
- 2012 - 2014 Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in an Alzheimer's disease mouse model.
- 2011 - 2014 Analysis of maternal recognition through embryo-specific sugar antigen and its inducing mechanisms for embryo implantation and placentation
- 2011 - 2014 Pathophysiological roles of nardilysin, critical factor for axonal maturation and myelination
- 2011 - 2013 細胞外ドメインシェディングによるシグナル伝達制御の病態における意義
- 2011 - 2012 Molecular Mechanism of Unconventional Secretory Pathway for "Leaderless" Proteins
- 2010 - 2010 免疫系による発生初期胚の認識機構-透明帯を利用した哺乳類の着床誘導戦略の証明-
- 2008 - 2010 Analysis of tissue remodeling mechanisms by circulating blood cells during human reproduction
- 2008 - 2010 Identification of NRDc, a novel key molecule for energy metabolism. Pathophysiological role of NRDc in Metabolic Syndrome
- 2008 - 2010 The role of nardilysin in body temperature homeostasis
- 2008 - 2008 体温による生体防御反応の制御機構:変温マウスを用いた解析
- 2007 - 2008 Analysis of molecular mechanisms and further development of a new therapy for infertile patients with repeated implantation failure using autologous peripheral blood mononuclear cells
- 2007 - 2008 肺細菌感染症における宿主膜タンパク質シェディング誘導の病態生理学的意義の解明
- 2006 - 2007 A novel molecular mechanism for ectodomain shedding
- 2006 - 2007 Analysis of mechanisms fix human embryo implantation by crosstalk between mother and embryo through endocrine and immune system network
- 2004 - 2005 Biological significances of metalloproteases which specific ally bind to membrane-anchored growth factors
- 2004 - 2005 Molecular biological analysis of mechanisms for human embryo implantation and placentation-from the perspectrives of repulsive force, chemoattractants and membrane-bound peptidases
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Papers (79):
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Yoshiaki Isomura, Mikiko Ohno, Satoshi Sudo, Mayuko Ono, Yuki Kaminishi, Yukiyoshi Sumi, Atsushi Yoshimura, Kumiko Fujii, Kazufumi Akiyama, Eiichiro Nishi, et al. Associations among plasma markers for N-methyl-d-aspartate receptor hypofunction, redox dysregulation, and insufficient myelination in patients with schizophrenia. Heliyon. 2024. 10. 9. e30193
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Bo-Shi Zhang, Xiao-Meng Zhang, Masaaki Ito, Satoshi Yajima, Kimihiko Yoshida, Mikiko Ohno, Eiichiro Nishi, Hao Wang, Shu-Yang Li, Masaaki Kubota, et al. JMJD6 Autoantibodies as a Potential Biomarker for Inflammation-Related Diseases. International journal of molecular sciences. 2024. 25. 9
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Mend Amar Batbaatar, Takeshi Kinoshita, Shinya Ikeda, Kiyoto Nishi, Hirotaka Iwasaki, Narangerel Ganbaatar, Mikiko Ohno, Eiichiro Nishi. Nardilysin in vascular smooth muscle cells controls blood pressure via the regulation of calcium dynamics. Biochemical and biophysical research communications. 2024. 712-713. 149961-149961
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Mikiko Ohno, Hiroki Shiomi, Osamu Baba, Mariko Yano, Takanori Aizawa, Yukiko Nakano-Matsumura, Shintaro Yamagami, Masashi Kato, Masanobu Ohya, Po-Min Chen, et al. Auxiliary roles of nardilysin in the early diagnosis of acute coronary syndrome: a prospective cohort study, the Nardi-ACS study. Internal and emergency medicine. 2024. 19. 3. 649-659
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Kenji Nakatsuma, Neiko Ozasa, Mikiko Ohno, Hiroshi Ishiguro, Manabu Minami, Eiichiro Nishi, Masakazu Toi, Koh Ono, Takeshi Kimura. Subclinical myocardial damage after anthracycline chemotherapy in Japanese patients with breast Cancer. Journal of Cardiology. 2024
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MISC (150):
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大野美紀子, 松浦博, 西清人, 糀谷泰彦, 牧山武, 池田真也, 西英一郎. M16メタロエンドペプチダーゼによる心拍数制御機構. 日本循環薬理学会口演要旨集. 2024. 33rd
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Ohno Mikiko, Nishi Kiyoto, Matsuura Hiroshi, Makiyama Takeru, Koujitani Hirohiko, Matsuda Shintaro, Kimura Takeshi, Nishi Eiichiro. Metalloprotease Nardilysin regulates sinus automaticity through transcriptional regulation of ion channels. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 3-O-110
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大野美紀子, 西清人, 大林徹也, 西英一郎. ナルディライジン酵素活性の生体内における意義. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2022. 27th
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西清人, 岩崎広高, 大野美紀子, 西英一郎. 肝細胞のナルディライジンは褐色脂肪組織の熱産生を制御する. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2022. 27th
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平岡 義範, 古市 真唯, 鎌田 真由子, 斉藤 沙樹, 久米 典昭, 吉種 光, 深田 吉孝, 池田 正明, 西 英一郎. ナルディライジンによる核内受容体ROR/REV-ERB活性調節機構. 日本薬学会年会要旨集. 2021. 141年会. 27P02-137
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Patents (4):
Books (8):
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創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術
技術情報協会 2021 ISBN:4861048567
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がん基盤生物学 -革新的シーズ育成に向けて-
南山堂 2013
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Nardilysin (MS: 328)
The Handbook of Proteolytic Enzymes (The 3rd Edition), 20 Dec 2012 Edited by Neil D. Rawlings and Guy Salvesen Academic Press 2012
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心臓血管外科Knack & Pitfalls、冠動脈外科の要点と盲点(第2版)
文光堂 2012
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健康長寿大事典ーEBMからQOLまでー
西村書店 2012
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Professional career (1):
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