Rchr
J-GLOBAL ID：201401061970907910
Update date: Oct. 11, 2024
AKIRA SUGIYAMA
スギヤマ アキラ | AKIRA SUGIYAMA
Affiliation and department：
Job title：
助教
Research field (2)：
Tumor diagnostics and therapeutics
, Molecular biology
Research theme for competitive and other funds (9)：
- 2023 - 2026 α線放出核種と抗体ドラッグデリバリーシステムによる新規放射性医薬品の開発
- 2023 - 2026 薬物送達システムとα線放出核種を組み合わせた革新的な白血病治療法の開発
- 2022 - 2025 もつれ光子対放出原子核と分子プローブの創成による生体内化学環境の医療診断
- 2021 - 2024 Creation of Next Generation Antibody Drug Conjugate Therapeutics for Advanced Cancer
- 2020 - 2023 がん幹細胞をターゲットとしたα線放出核種を用いた革新的な白血病治療法の開発
- 2020 - 2023 Optimization of pretargeted alpha therapy for multiple types of cancer
- 2019 - 2022 超選択的デリバリー短寿命α線を用いた胃癌腹膜播種内照射療法の実験的検討
- 2018 - 2021 短寿命α線医薬品製造工程における被ばくを抑制するロボティック精製・標識技術の開発
- 2013 - 2015 study of low-immunogenic monomeric streptavidin
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Papers (41)：
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Toshifumi Tatsumi, Songji Zhao, Akitomo Kasahara, Miho Aoki, Ken-ichi Nishijima, Naoyuki Ukon, Tatsuhiko Kodama, Kazuhiro Takahashi, Akira Sugiyama, Kohshin Washiyama, et al. In vivo-stable bis-iminobiotin for targeted radionuclide delivery with the mutant streptavidin. Bioorganic & Medicinal Chemistry Letters. 2024. 129803-129803
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Kenji Shimazoe, Kim Donghwan, Tomoko Mineo, Takeshi Sato, Seiichi Ohta, Toshifumi Tatsumi, Akira Sugiyama, Kenzo Yamatsugu, Sachiyo Nomura, Ryohei Terabayashi, et al. pH dependence of perturbed angular correlation in DOTA chelated In-111 measured with ring-shape gamma-ray detectors. Interactions. 2024. 245. 1
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Juri Sakata, Toshifumi Tatsumi, Akira Sugiyama, Akihiro Shimizu, Yuya Inagaki, Hiroto Katoh, Takefumi Yamashita, Kazuki Takahashi, Sho Aki, Yudai Kaneko, et al. Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin. Protein expression and purification. 2023. 106375-106375
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Yuta Tani, Morihito Takita, Yurie Kobashi, Masatoshi Wakui, Tianchen Zhao, Chika Yamamoto, Hiroaki Saito, Moe Kawashima, Sota Sugiura, Yoshitaka Nishikawa, et al. Varying Cellular Immune Response against SARS-CoV-2 after the Booster Vaccination: A Cohort Study from Fukushima Vaccination Community Survey, Japan. Vaccines. 2023. 11. 5
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Moe Kawashima, Hiroaki Saito, Takamitsu Nishiuchi, Hiroki Yoshimura, Masatoshi Wakui, Yuta Tani, Yoshitaka Nishikawa, Fumiya Omata, Morihito Takita, Tianchen Zhao, et al. Antibody and T-Cell Responses against SARS-CoV-2 after Booster Vaccination in Patients on Dialysis: A Prospective Observational Study. Vaccines. 2023. 11. 2. 260-260
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MISC (30)：
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久下恒明, 久下恒明, 増田寛喜, 増田寛喜, 杜婉瑩, 保田智彦, 保田智彦, 杉山暁, 羽場宏光, 巽俊文, et al. The promising option of At211-labeled anti-FGFR4 antibody on the dissemination of gastric cancer in immunocompetent mice. 日本癌学会学術総会抄録集(Web). 2023. 82nd
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高橋和希, 巽俊文, 石井正純, 田中十志也, 児玉龍彦, 杉山暁, 杉山暁, 山次健三, 金井求. Functional-protein-Drug Conjugates with Photoresponsive Self-inactivation Mechanisms. 日本薬学会年会要旨集(Web). 2023. 143rd
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坂田樹里, 巽俊文, 山次健三, 児玉龍彦, 金井求, 徳山英利, 杉山暁. Antibody Mimetic Drug Conjugateによるがん治療法開発. 日本抗体学会学術大会プログラム・抄録集(Web). 2023. 2nd
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巽俊文, 山次健三, 杉山暁, 趙松吉, 粟生木美穂, 西嶋剣一, 右近直之, 下山彩希, 譚成博, 城寶大輝, et al. 低免疫原性ストレプトアビジン変異体と改変ビオチンを用いるプレターゲティングシステムの開発. 放射化学. 2023. 47
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Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki, Taiki Joho, et al. Synthesis and Astatine Labeling of a bis-iminobiotin derivative with enhanced plasma stability. NUCLEAR MEDICINE AND BIOLOGY. 2022. 108. S121-S121
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Patents (7)：
Association Membership(s) (2)：
JAPANESE CANCER ASSOCIATION
, Japanese Society of Nuclear Medicine
