Rchr
J-GLOBAL ID:201501029844998809   Update date: Jul. 16, 2024

Tanimizu Naoki

タニミズ ナオキ | Tanimizu Naoki
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): https://kaken.nii.ac.jp/d/r/00333386.ja.html
Research field  (3): Experimental pathology ,  Morphology, anatomy ,  General surgery, pediatric surgery
Research keywords  (30): 3次元培養 ,  胆管上皮細胞 ,  肝臓 ,  組織形成 ,  胆管 ,  肝前駆細胞 ,  管腔構造 ,  幹細胞 ,  培養 ,  サンドウィッチ ,  細胞 ,  上皮細胞 ,  チューブ構造 ,  肝臓発生 ,  形態形成 ,  サンドウィッチ培養 ,  共培養 ,  細胞移植 ,  肝発生 ,  小型肝細胞 ,  肝組織形成 ,  肝再生 ,  スキャフォールド ,  サイトカイン ,  毛細胆管 ,  組織化 ,  成熟化 ,  CD44 ,  類肝組織 ,  癌細胞
Research theme for competitive and other funds  (20):
  • 2024 - 2027 移植医療に貢献可能なiPS細胞オルガノイドを駆使したヒト臓器創出技術の開発
  • 2020 - 2023 Establishment of hepatobiliary connection ex vivo
  • 2018 - 2023 Comprehensive analysis of 3D nuclear gene position involved in malignant transformation of hypoxic cancer
  • 2018 - 2021 Renewal of severely damaged livers by activating hepatic progenitor cells
  • 2017 - 2020 Translational research for clinical apply using liver stem cells from cell banking
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Papers (49):
  • Norihisa Ichinohe, Naoki Tanimizu, Keisuke Ishigami, Yusuke Yoshioka, Naoki Fujitani, Takahiro Ochiya, Motoko Takahashi, Toshihiro Mitaka. CINC-2 and miR-199a-5p in exosomes secreted by transplanted Thy1+ cells activate hepatocytic progenitor cell growth in rat liver regeneration. 2023
  • Yuta Koui, Misao Himeno, Yusuke Mori, Yasuhiro Nakano, Eiko Saijou, Naoki Tanimizu, Yoshiko Kamiya, Hiroko Anzai, Natsuki Maeda, Luyao Wang, et al. Development of human iPSC-derived quiescent hepatic stellate cell-like cells for drug discovery and in vitro disease modeling. Stem cell reports. 2021. 16. 12. 3050-3063
  • Naoki Tanimizu, Norihisa Ichinohe, Yasushi Sasaki, Tohru Itoh, Ryo Sudo, Tomoko Yamaguchi, Takeshi Katsuda, Takafumi Ninomiya, Takashi Tokino, Takahiro Ochiya, et al. Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo. Nature communications. 2021. 12. 1. 3390-3390
  • Norihisa Ichinohe, Masayuki Ishii, Naoki Tanimizu, Toru Mizuguchi, Yusuke Yoshioka, Takahiro Ochiya, Hiromu Suzuki, Toshihiro Mitaka. Extracellular vesicles containing miR-146a-5p secreted by bone marrow mesenchymal cells activate hepatocytic progenitors in regenerating rat livers. Stem cell research & therapy. 2021. 12. 1. 312-312
  • Naoki Tanimizu, Norihisa Ichinohe, Hiromu Suzuki, Toshihiro Mitaka. Prolonged oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice. Aging. 2020. 12. 19. 18907-18927
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MISC (9):
more...
Professional career (1):
  • 博士(農学) (京都大学)
Work history (1):
  • 2009 - 2013 Sapporo Medical University School of Medicine
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