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J-GLOBAL ID：201501049293570455   Update date: Nov. 19, 2024

Mineharu Yohei

Mineharu Yohei
Affiliation and department：
Kyoto University Department of Artificial Intelligence in Healthcare and Medicine

About Kyoto University Department of Artificial Intelligence in Healthcare and Medicine


Job title： Professor, associate
Other affiliations (1)：
Homepage URL  (1)： https://kyouindb.iimc.kyoto-u.ac.jp/j/mU6qD
Research field  (4)： Genomics ,  Healthcare management, medical sociology ,  Tumor diagnostics and therapeutics ,  Neurosurgery
Research keywords  (8)： medulloblastoma ,  genetic epidemiology ,  glioma ,  malignant brain tumor ,  moyamoya disease ,  brain tumor ,  genetics ,  immunotherapy
Research theme for competitive and other funds  (21)：
  • 2023 - 2026 個別最適化した疾患発症予防支援アプリによる健康行動アドヒアランス向上の要件の解明
  • 2023 - 2026 神経膠腫に対するロムスチン療法とプロカルバジン、ロムスチン、ビンクリスチン併用療法に関する研究開発
  • 2023 - 2026 高齢者初発膠芽腫に対する分子分類に応じたテモゾロミド併用寡分割放射線治療の最適化に関する研究開発
  • 2022 - 2025 Lipid metabolism regulator RNF213 and immune evasion mechanisms in medulloblastoma
  • 2022 - 2025 Functions of IL-1B in preclinical models of RNF213-related angiopathy
Show all
Papers (191)：
  • Tomoki Sasagasako, Akihiko Ueda, Yohei Mineharu, Yusuke Mochizuki, Souichiro Doi, Silsu Park, Yukinori Terada, Noritaka Sano, Masahiro Tanji, Yoshiki Arakawa, et al. Postoperative Karnofsky performance status prediction in patients with IDH wild-type glioblastoma: A multimodal approach integrating clinical and deep imaging features. PLOS ONE. 2024
  • Tomoki Sasagasako, Yohei Mineharu, Takeshi Funaki, Yasutaka Fushimi, Hideo Chihara, Silsu Park, Kota Nakajima, Yasuzumi Matsui, Masakazu Okawa, Takayuki Kikuchi, et al. RNF213 Mutation Associated with the Progression from Middle Cerebral Artery Steno-Occlusive Disease to Moyamoya Disease. Translational stroke research. 2024
  • Shintaro Nakayasu, Masahiro Tanji, Megumi Uto, Yasuhide Takeuchi, Yasuhide Makino, Etsuko Yamamoto Hattori, Yukinori Terada, Noritaka Sano, Yohei Mineharu, Takashi Mizowaki, et al. Hypofractionated radiotherapy combined with bevacizumab plus low-dose ifosfamide, carboplatin, and etoposide as second-line chemoradiotherapy for progressing spinal diffuse midline glioma, H3K27-altered: illustrative case. Journal of neurosurgery. Case lessons. 2024. 8. 7
  • Shunya Kashiwagi, Masahiro Tanji, Toshiki Matsuoka, Noritaka Sano, Hiroaki Ozasa, Daisuke Natori, Yasuhide Takeuchi, Yasuhide Makino, Etsuko Yamamoto Hattori, Yukinori Terada, et al. Trochlear nerve schwannoma with concomitant osimertinib-responsive stage IV lung adenocarcinoma: illustrative case. Journal of neurosurgery. Case lessons. 2024. 8. 7
  • Shigeki Takada, Yasuhide Takeuchi, Yasuhide Makino, Etsuko Yamamoto, Noritaka Sano, Masahiro Tanji, Yohei Mineharu, Yoshiki Arakawa. AB014. The accurate classification of high-grade glioma, IDH-wildtype, is based on methylation profiling: a case report. Chinese clinical oncology. 2024. 13. Suppl 1. AB014
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MISC (252)：
  • 佐野徳隆, 丹治正大, 寺田行範, 峰晴陽平, 荒川芳輝. トルコ鞍部嚢胞性疾患に対する腹部脂肪充填術の治療成績. 日本間脳下垂体腫瘍学会プログラム・抄録集. 2024. 34th
  • 駒木美紗, 上田敬太, 上田敬太, 荒川芳輝, 丹治正大, 峰晴陽平, 植野司, 梅田雄嗣, 草野佑介, 村井俊哉, et al. 間脳・下垂体腫瘍患者の社会的行動障害を含む高次脳機能障害と社会参加の関連. 高次脳機能研究. 2024. 44. 1
  • 押沙織, 山脇理恵, 山尾幸広, 田嶋あゆみ, 峰晴陽平, 荒川芳輝, 松田秀一, 村井俊哉. 補足運動野を含む前頭葉神経膠腫摘出術後3症例の言語障害の質的特徴. 高次脳機能研究. 2024. 44. 1
  • 峰晴陽平, 峰晴陽平, 笹ヶ迫知紀, 笹ヶ迫知紀, 植田彰彦, 望月勇佑, 沼侑佐, 土井聡一郎, 荒川芳輝, 奥野恭史, et al. Prediction of KPS deterioration in glioblastoma using multimodal learning with pre- and post-operative MRI images and clinical information. 日本脳腫瘍学会学術集会プログラム・抄録集. 2023. 41st
  • 鎌田貴彦, 鎌田貴彦, 峰晴陽平, 松井恭澄, 手塚徹, 尾市雄輝, 森本貴昭, 丹治正大, 佐野徳隆, 寺田行範, et al. Absence of RNF213 in medulloblastoma induces starvation resistance via GAS6 and results in tumor progression. 日本脳腫瘍学会学術集会プログラム・抄録集. 2023. 41st
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Patents (1)：
Books (4)：
  • Moyamoya Disease Explored Through RNF213: Genetics, Molecular Pathology, and Clinical Sciences.
    Springer 2017
  • 脳神経外科プラクティス6「脳神経外科医が知っておくべきニューロサイエンスの知識」
    文光堂 2015
  • 脳神経外科プラクティス5「無症候性脳血管障害を解く」
    文光堂 2015
  • TUMORS OF THE CENTRAL NERVOUS SYSTEM, Volume 13
    Springer 2014
Lectures and oral presentations  (7)：
  • 脳動脈瘤の遺伝子解析は血管障害の臨床と研究に如何に貢献するか
    (第49回日本動脈硬化学会学術集会 2017)
  • Synergistic Effects of Regulatory and Memory T Cell Modulation in Dendritic Cell-Based Immunotherapy: Impact of mTOR and NFkB Pathway
    (ICBTRT 2016)
  • Genetics of moyamoya disease: paradigm shift and future prospects.
    (World Federation of Neurosurgical Society 15th World Congress of Neurosurgery 2013)
  • Genetics of Stroke
    (San Fransisco Bay Area Seminar 2010)
  • Genetic background of intracranial aneurysm and moyamoya disease
    (UCSF Center for Cerebrovascular Research Seminar 2010)
ｍore...
Education (2)：
  • 2004 - 2008 Kyoto University Graduate School of Medicine
  • 1995 - 2001 Kyoto University School of Medicine
Professional career (1)：
  • Ph.D. (Kyoto University Graduate School of Medicine)
Work history (3)：
  • 2021/06 - 現在 Kyoto University Department of Artificial Intelligence in Healthcare and Medicine Associate Professor
  • 2015/04 - 2021/05 Kyoto University Graduate School of Medicine Department of Neurosurgery Professor (assistant)
  • 2008/09 - 2011/08 Cedars-Sinai Medical Center Gene Therapeutic Research Institute Postdoctoral fellow
Committee career (4)：
  • 2023/04 - 現在 脳腫瘍病理学会 評議員
  • 2015 - 現在 もやもや病(ウィリス動脈輪閉塞症)の診断・治療に関する研究班 研究協力者
  • 2023/11 - 2026/10 日本神経内視鏡学会 技術認定制度委員
  • 2016/04 - 2018/03 京都大学 学融合フェロー
Awards (1)：
  • 2011/05 - Cedars-Sinai Medical Center Maleniak Award for Excellence of Postdoctoral Research
Association Membership(s) (12)：
Japanese Association for Medical Artificial Intelligence ,  Japanse Society for Bioinformatics ,  血管生物学医学会 ,  日本神経内視鏡学会 ,  The Mt. Fuji Workshop on CVD ,  The Japan Society of Brain Tumor Pathology ,  The Japanese Congress for Brain Tumor Surgery ,  The Japan Society for Neuro-Oncology ,  The Japanese Society for Surgery on Cerebral Stroke ,  The Japanese Society for Neuroendovascular Therapy ,  The Japan Stroke Society ,  The Japan Neurosurgical Society
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