Research theme for competitive and other funds (3)：
2018 - 2021 Analysis of the mechanism that inflammation-inducible DC subset enhances the survival of B cells
2013 - 2016 Search for new molecules controlling the response of nucleic acid-sensing TLRs
2010 - 2011 Analysis of the mechanism for controlling reciprocal balance in nucleic acid sensing-innate immune system
Papers (50)：
Kensuke Miyake, Takuma Shibata, Ryutaro Fukui, Yusuke Murakami, Ryota Sato, Ryosuke Hiranuma. Endosomal Toll-Like Receptors as Therapeutic Targets for Autoimmune Diseases. Advances in experimental medicine and biology. 2024. 1444. 97-108
Ryosuke Hiranuma, Ryota Sato, Kiyoshi Yamaguchi, Satoshi Nakamizo, Kenichi Asano, Takuma Shibata, Ryutaro Fukui, Yoichi Furukawa, Kenji Kabashima, Kensuke Miyake. Aberrant monocytopoiesis drives granuloma development in sarcoidosis. International Immunology. 2023
Gang Liu, Tatt Jhong Haw, Malcolm R Starkey, Ashleigh M Philp, Stelios Pavlidis, Christina Nalkurthi, Prema M Nair, Henry M Gomez, Irwan Hanish, Alan Cy Hsu, et al. TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase. Nature communications. 2023. 14. 1. 7349-7349
Ryota Sato, Kaiwen Liu, Takuma Shibata, Katsuaki Hoshino, Kiyoshi Yamaguchi, Toru Miyazaki, Ryosuke Hiranuma, Ryutaro Fukui, Yuji Motoi, Yuri Fukuda-Ohta, et al. Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5Lhihepatic macrophages. 2023
