Rchr
J-GLOBAL ID:201601005126894363   Update date: May. 31, 2024

Kashiwakura Junichi

カシワクラ ジュンイチ | Kashiwakura Junichi
Affiliation and department:
Job title: Professor
Research field  (5): Cell biology ,  Molecular biology ,  Allergies and connective tissue disease ,  Immunology ,  Pharmaceuticals - health and biochemistry
Research theme for competitive and other funds  (5):
  • 2024 - 2027 マスト細胞活性化反応におけるSTAP-1抑制機構の解明
  • 2021 - 2024 Analysis of function of STAP-1 for mast cell activation and pathogenesis of bronchial asthma
  • 2019 - 2022 Study of signaling pathways for treatment of immune/allergic diseases
  • 2015 - 2018 The role of HRF in pollinosis
  • 2013 - 2015 Investigation of HRF-mediated amplifying mechanism in food allergy
Papers (111):
  • Kota Kagohashi, Yuto Sasaki, Kiyotaka Ozawa, Takuya Tsuchiya, Shoya Kawahara, Kodai Saitoh, Michiko Ichii, Jun Toda, Yasuyo Harada, Masato Kubo, et al. Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation. The Journal of Immunology. 2024
  • Jun-Ichi Kashiwakura, Keigo Nishida. [Progressing Basic Immunology for Development of New Therapeutic Medicines]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2024. 144. 5. 473-474
  • Jun-Ichi Kashiwakura, Tadashi Matsuda. [Understanding New Regulatory Mechanism of TCR Signal Transduction]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2024. 144. 5. 497-501
  • Yuto Sasaki, Shoya Kawahara, Yuichi Sekine, Jun-Ichi Kashiwakura, Kenji Oritani, Tadashi Matsuda. Potential therapeutic applications of targeting signal-transducing adaptor protein-2 in autoimmune diseases. Exploration of Immunology. 2023. 3. 6. 604-612
  • Jun-Ichi Kashiwakura, Shoya Kawahara, Iori Inagaki, Kyosuke Inui, Kodai Saitoh, Kota Kagohashi, Yuto Sasaki, Fuki Kobayashi, Yuichi Kitai, Ryuta Muromoto, et al. STAP-2 negatively regulates BCR-mediated B cell activation by recruiting tyrosine-protein kinase CSK to LYN. FEBS letters. 2023. 597. 19. 2433-2445
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MISC (47):
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Patents (1):
Books (2):
  • Monomeric IgE and Mast cell Development, Survival and Function. Mast Cell Biology: Contemporary and Emerging Topics (Edited by Gilfillan A.M. and Metcalfe D.D.).
    Adv. Exp. Med. Biol. 2011
  • Selective downregulation of FcgammaRI and FcepsilonRI in cord blood-derived vs adult peripheral blood-derived cultured human mast cells (Edited by Bienenstock J., Ring J. and Togias A.G.).
    Allergy Frontiers and Futures. 2004
Lectures and oral presentations  (102):
  • STAP-2 negatively regulates B cell receptor-mediated B cell activation and allergic rhinitis.
    (第50回日本免疫学会総会・学術集会 2022)
  • New strategy of STAP-2-based suppression of TCR-mediated T cell activation and autoimmune encephalomyelitis.
    (第50回日本免疫学会総会・学術集会 2021)
  • STAP-1 is involved in TCR-mediated T cell activation and pathogenesis of multiple sclerosis.
    (第50回日本免疫学会総会・学術集会 2021)
  • 突発性肺線維症病態形成に対するアダプター分子STAP-2の機能解析
    (日本薬学会北海道支部第148回例会 2021)
  • STAP-2によるB細胞活性化制御機構の解明
    (日本薬学会北海道支部第148回例会 2021)
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Education (2):
  • 1997 - 2002 Hoshi University
  • 1993 - 1997 Hoshi University Hoshi University Hoshi University
Professional career (1):
  • 博士(薬学) (星薬科大学)
Work history (9):
  • 2022/04 - 現在 北海道大学 大学院薬学研究院
  • 2022/04 - 現在 Hokkaido University of Science Faculty of Pharmaceutical Sciences, Department of Life Science Professor
  • 2016/10 - 2022/03 Hokkaido University Faculty of Pharmaceutical Sciences Lecturer
  • 2016/04 - 2016/09 Nihon University School of Medicine Research Scientist
  • 2013/04 - 2016/03 RIKEN Center for Integrative Medical Sciences Senior Research Scientist
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Committee career (4):
  • 2023 - 現在 日本薬学会 代議員
  • 2021/01 - 現在 日本免疫学会 評議員
  • 2013/12 - 2016/03 RIKEN IMS-JSI 国際シンポジウム実行委員
  • 2010/10 - 2012/03 第61回日本アレルギー学会学術大会大会実行委員
Association Membership(s) (2):
THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY
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