Research theme for competitive and other funds (4)：
2022 - 2026 霊長類消化管オルガノイドを用いたホルモンと神経伝達物質の検出法の確立
2020 - 2022 Development of pancreatic fibrosis tissues for pancreatic cancers
2018 - 2020 Development of inflamed pancreatic islet tissues using human iPS cells derived pancreatic cells
2017 - 2019 Compartmentalized tumor spheroid culture system for localized anticancer drug treatment
Papers (43)：
Kotaro Doi, Hiroshi Kimura, Soo Hyeon Kim, Shohei Kaneda, Takehiko Wada, Tetsuhiro Tanaka, Akira Shimizu, Takanori Sano, Masatomo Chikamori, Marie Shinohara, et al. Enhanced podocyte differentiation and changing drug toxicity sensitivity through pressure controlled mechanical filtrating stress on a glomerulus-on-a-chip. Lab on a Chip. 2023
Jianyu He, Chang Zhou, Xiaolei Xu, Zhenzhen Zhou, Mathieu Danoy, Marie Shinohara, Wenjin Xiao, Dong Zhu, Xiuying Zhao, Xiaobin Feng, et al. Scalable Formation of Highly Viable and Functional Hepatocellular Carcinoma Spheroids in an Oxygen-Permeable Microwell Device for Anti-Tumor Drug Evaluation. Advanced Healthcare Materials. 2022. 11. 18. 2200863-2200863
Hyunjin Choi, Marie Shinohara, Masato Ibuki, Masaki Nishikawa, Yasuyuki Sakai. Differentiation of Human-Induced Pluripotent Stem Cell-Derived Endocrine Progenitors to Islet-like Cells Using a Dialysis Suspension Culture System. CELLS. 2021. 10. 8
Amal Essaouiba, Rachid Jellali, Marie Shinohara, Benedikt Scheidecker, Cécile Legallais, Yasuyuki Sakai, Eric Leclerc. Analysis of the behavior of 2D monolayers and 3D spheroid human pancreatic beta cells derived from induced pluripotent stem cells in a microfluidic environment. Journal of biotechnology. 2021. 330. 45-56
Marie Shinohara, Hiroshi Arakawa, Yuuichi Oda, Nobuaki Shiraki, Shinji Sugiura, Takumi Nishiuchi, Taku Satoh, Keita Iino, Sylvia Leo, Yusuke Kato, et al. Coculture with hiPS-derived intestinal cells enhanced human hepatocyte functions in a pneumatic-pressure-driven two-organ microphysiological system. Scientific reports. 2021. 11. 1. 5437-5437
篠原満利恵, YOU Lau Qiao, YOU Lau Qiao, 前田夏希, 前田夏希, BENEDIKT Scheidecker, BENEDIKT Scheidecker, 木村圭一, 木村圭一, ASTIA Safitri Rizki, et al. 酸素透過性培養基板を用いた肝組織形成. 日本再生医療学会総会(Web). 2019. 18th
JAPANESE SOCIETY FOR ALTERNATIVES TO ANIMAL EXPERIMENTS
, The Japanese Society for the Research of Hepatic Cells
, THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
